Vestibulodynia: Pain in the opening of the Vagina - Clinical Trial
What is the Purpose of this Study?
We are doing this study to learn what treatments work best for women who have Vestibulodynia (pain at the vaginal opening).
Vestibulodynia (vaginal pain study)
Who Can Participate in the Study?
-Diagnosed with vestibulodynia or think you may have vestibulodynia (vaginal pain)
-Not currently using vaginal cream with lidocaine or estradiol
What is Involved?
If you choose to join this study you will:
-Be randomized (like drawing numbers out of a hat) to 1 of 4 groups:
--Group 1 will get medicated vaginal cream and a pill (Nortriptyline)
--Group 2 will get medicated vaginal cream and a placebo pill (a harmless pill that does nothing)
--Group 3 will get vaginal placebo cream (a cream that does nothing) and a pill (Nortriptyline)
--Group 4 will get vaginal placebo cream and a placebo pill
Everyone will be asked to:
-Have blood draws
-Have a vaginal exam to collect samples
-Complete 4 clinic visits at UNC Hospitals in Hillsborough over 6 months