Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments (Vestibulod - Clinical Trial
What is the Purpose of this Study?
Who Can Participate in the Study?
-Diagnosed with vestibulodynia or think you may have vestibulodynia (vaginal pain)
-Not currently using vaginal cream with lidocaine or estradiol
What is Involved?
If you choose to join this study you will:
-Be randomized (like drawing numbers out of a hat) to 1 of 4 groups:
--Group 1 will get medicated vaginal cream and a pill (Nortriptyline)
--Group 2 will get medicated vaginal cream and a placebo pill (a harmless pill that does nothing)
--Group 3 will get vaginal placebo cream (a cream that does nothing) and a pill (Nortriptyline)
--Group 4 will get vaginal placebo cream and a placebo pill
Everyone will be asked to:
-Have blood draws
-Have a vaginal exam to collect samples
-Complete 4 clinic visits at UNC Hospitals in Hillsborough over 6 months