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CLOVERS: Early Resuscitation in Sepsis - Clinical Trial

What is the Purpose of this Study?

We are doing this study to determine the best treatment strategy for patients with low blood pressure caused by a severe infection.
What is the Condition Being Studied?
Low blood pressure due to a serious infection

Who Can Participate in the Study?

Adults presenting to the Emergency Department who are have low blood pressure caused by a serious infection.

Age Group

What is Involved?

If you agree to be in this study you will:
- Be randomized (like the flip of a coin) to receive:
---A) Medicine to raise your blood pressure before being given fluids OR
---B) A larger amount of fluids first and then medicine to raise your blood pressure

Study Details

Full Title
Crystalloids Liberal Or Vasopressors Early Resuscitation in Sepsis (CLOVERS)
Principal Investigator
Emergency Medicine Specialist
Protocol Number
IRB: PRO00100074
NCT: NCT03434028
Phase III
Contact the Duke Recruitment Innovation Center