BLU-285-1303 for Metastatic Gastrointestinal Stromal Tumor - Clinical Trial
What is the Purpose of this Study?
We are doing this study to find out if a drug called avapritinib (BLU-285) will work against GIST.
Locally advanced or advanced GIST (Gastrointestinal stromal tumor)
Who Can Participate in the Study?
Adults with GIST tumor who:
- Are locally advanced, but cannot be removed by surgery
- Advanced (spread throughout the body)
Disease has gotten worse on prior therapies with drugs called tyorisine kinase inhibitors (no more than 3 kinds)
What is Involved?
If you choose to join this study, you will:
-Be randomized (like the flip of a coin) to take either avapritinib or regoarafenib by the mouth every day.
- Have study visits once a month at Duke