EV-201 for Advanced Bladder Cancer - Clinical Trial
What is the Purpose of this Study?
We are doing this study to find out if enfortumab vedotin will work for patients with advanced urothelial cancer who have been previously treated with an immunotherapy.
Advanced Bladder Cancer (Urothelial Cancer)
Who Can Participate in the Study?
Adult patients with advanced bladder cancer who have gotten an immunotherapy but have not gotten chemotherapy.
What is Involved?
If you choose to join this study, you will:
- Have a screening visit that includes a blood draw, urine collection, eye exam, and imaging scans
Once you have completed the screening phase, you will:
- Have physical exams, blood tests, questions about your medications and side effect, and an imaging scan will be done every 8 weeks at your study visits
- Get the study drug enfortumab vedotin as an infusion in 28 day cycles.
-- You will get study drug on days 1, 8 and 15 of each cycle
-- Each cycle will require at least 3 visits to Duke
As long as you are not experiencing major side effects and the imaging scans show that your cancer is under control, you will continue to have study visits and get the study treatment.
After you finish all the study visits and have finished the study treatment, you will be contacted about every 3 months to see how you are doing and to see what other cancer therapies you may be on.