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LGG-14C03 for Low Grade Glioma - Clinical Trial

What is the Purpose of this Study?

We are doing this study to learn and understand if the chemotherapy drug called carboplatin works as well as the standard therapy. The standard therapy for low grade glioma in children and young adults is using a combination of carboplatin and vincristine.

This study will try to understand if treatment with carboplatin alone improves quality of life for patients with low grade glioma and their families.

What is the Condition Being Studied?

Brain cancer (low grade glioma)

Who Can Participate in the Study?

Patients who:
- Are less than 21 years old
- Are newly or previously diagnosed with a low grade brain tumor, such as glioma

Age Group
Adults, Children

What is Involved?

If you choose to join this study, you will:
-Be randomly assigned (like the flip of a coin) to get one of two treatments:
-- A combination of the chemotherapy drugs carboplatin and vincristine
-- The chemotherapy drug carboplatin by itself

Study Details

Full Title
A Phase III Study Comparing Two Carboplatin Containing Regimens for Children and Young Adults with Previously Untreated Low Grade Glioma
Principal Investigator
Protocol Number
IRB:PRO00088729
NCT:NCT02455245
Phase
Phase III
ClinicalTrials.gov
Contact the Duke Recruitment Innovation Center
MyResearchPartners@duke.edu
or
919-681-5698