Altitude Diving for Decompression Sickness in Healthy People - Clinical Trial
What is the Purpose of this Study?
We are doing this study to improve the safety of diving underwater while at altitude (e.g., diving in a lake high in the mountains).
Decompression Sickness in Healthy People
Who Can Participate in the Study?
Adults age 18-40 who:
- Are generally healthy and physically fit
- Don't smoke
- Don't have heart or lung disease (including high blood pressure or airway obstruction),
- Don't have a seizure disorder, history of middle ear or sinus disease or high altitude cerebral or pulmonary edema (HACE, HAPE)
- Are unable to to perform middle ear autoinflation ('clear' your ears)
- Don't have anemia, sickle cell disease and sickle cell trait
- Aren't pregnant
What is Involved?
If you choose to be in the study you will:
- Have a half-day screening visit including an exercise test to determine fitness
- Spend 60 hours continuously in a hypobaric chamber at simulated altitudes of 10000 or 12000 ft
- Have blood and urine samples taken periodically throughout the altitude exposure
- Complete questionnaires periodically to determine if there are any effects of altitude
- Complete a 20 or 25 min dive to a depth of about 90 feet in warm water with light exercise with return to altitude
- Have ultrasound testing after the dive to monitor if there are any effects of the dive
- Be able to read and use an electronic device (tablets) during down-time