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Differences in the female urinary microbiome before and after menopause - Clinical Trial

What is the Purpose of this Study?

We are doing this study to learn whether the urinary microbiome (bacteria that normally lives in the bladder) are different before and after menopause.

By understanding how the urinary microbiome works in these situations, we may be able to develop new treatment options for bladder conditions in the future.

What is the Condition Being Studied?

Urinary Tract Infections (UTI)

Who Can Participate in the Study?

Adult women who:
- Are aged 30 and older. Ages 30-45 may not have had a UTI within the previous 6 months
- Do not have a history of long-term use of steroids
- Do not have a history of breast cancer in the last 5 years

Age Group
Adults

What is Involved?

If you choose to join this study, you will:
- Complete questionnaires about your demographics and medical information
- Provide a urine sample collected from a tube inserted into your bladder
- Have a vaginal swab sample
- Most women will be asked to complete only one visit. Women with recurrent UTIs may be asked to provide the same samples in a second visit 4 months later.

Study Details

Full Title
Evaluation of the urinary microbiome with aging and in menopausal women with recurrent urinary tract infections
Principal Investigator
Protocol Number
IRB:PRO00083917
Contact the Duke Recruitment Innovation Center
MyResearchPartners@duke.edu
or
919-681-5698