Urinary Microbiome in Women with Frequent UTI - Clinical Trial
What is the Purpose of this Study?
We are doing this study to learn whether the urinary microbiome (all the micro-organisms like bacteria and viruses in the urinary tract) is different in menopausal women with recurrent urinary tract infections, compared to women of a similar age without recurrent urinary tract infections. By understanding how the urinary microbiome works in these situations, we may be able to develop new medicine options in the future.
Urinary Tract Infections
Who Can Participate in the Study?
Adult women age 55 or older who:
- Have a history of recurrent urinary tract infections
- Are using vaginal estrogen (6 weeks)
- Have at least 2 recurrent urinary tract infections proven by urine culture within 6 months or 3 within a year.
- Are willing to stop any probiotics or UTI prevention supplements for the study
Adult age women from 30-45 or 55 and older who
- Have a history of NO recurrent urinary tract infections with NO evidence of a urinary tract infection within the previous 6 months.
- Don't have a history of long-term use of steroids.
- Don't have a history of breast cancer in the last 5 years.
What is Involved?
If you choose to join this study you will:
- Complete questionnaires about your demographics (your age, gender, race, ethnicity, where you live, etc.) and medical information.
- Provide a urine sample collected from a tube inserted into your bladder at two separate visits 4 months apart.