Lifespan Emotion Regulation in MDD (For Depression) - Clinical Trial
What is the Purpose of this Study?
We also want to know if the ability to regulate negative emotions can help us understand who might experience depression in the future so better treatments can be developed.
Depression and healthy adults age 35-75
Who Can Participate in the Study?
Adults age 35-75 who:
- Have been feeling depressed or down most of the day, nearly every day for the past two weeks or more OR Do not have a current or lifetime history of mental illness (i.e. depression or anxiety)
- Can safely have an MRI scan (for example, no known neurological conditions, no metal in the body, not pregnant, not claustrophobic)
- Do not have a history of moderate or severe substance abuse
- do not currently take psychiatric medication OR currently taking psychiatric medications at the same dose for the past 4 weeks with no intent of changing medication and/or dose
What is Involved?
If you choose to join this study, you will
- Have 3 in-person study visits and 2 sets of follow-up surveys and questionnaires, including:
-- An assessment visit for an in-depth mental and physical health interview that will take 1-4 hours
-- A second visit that will include completing 2 computer tasks and writing down memories from your past (this will take about 2 hours)
-- A third visit for an MRI scan during which you will be asked to complete certain tasks (this visit will take about 2 hours)
-- At 6 months and 12 months after the MRI, you will be asked to complete surveys and questionnaires -- this can be done over the phone, online or through regular mail
We are doing this this research study to better understand how people effectively regulate negative emotions.