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APPRAISE ATP Study for Internal Cardiac Defibrillator Patients - Clinical Trial

What is the Purpose of this Study?

We are doing this study to better understand the value of setting an internal cardiac defibrillator (ICD) to anti-tachycardia pacing (ATP) for patients like you. This study is to see if certain programing will reduce the number of shocks received and improve survival rates.

What is the Condition Being Studied?

Heart disease requiring the implant of an internal cardiac defibrillator (ICD). 

Who Can Participate in the Study?

Patients over age 21 who will be receiving an implanted cardiac defibrillator (ICD) who:
- Are not on the active heart transplant list
- Do not currently have an implanted cardiac defibrillator device (ICD)
- Do not currently have a ventricular assist device (VAD) or are scheduled to receive a VAD  
- Are not receiving dialysis

Please contact the study team for more information about participating in the study.

Age Group
Adults

What is Involved?

If you choose to join the study, you will:
- Be scheduled to have an internal cardiac defibrillator implanted as part of our routine medical care

- Be randomized (like the flip of a coin) to one of two treatment groups:
-- Group 1: Your device will be set to deliver anti-tachycardia pacing (ATP) first and only deliver shock if needed
-- Group 2: Your device will deliver only shock treatments when needed (no ATP pacing)

The follow-up visits and information collected during the conduct of the study are routinely done by your doctor. Follow-up testing of your ICD will be done at the same intervals as if you were not in the study, about every 6 months until the study is over.      

Study Details

Full Title
Assessment of Primary Prevention Patients Receiving An ICD-Systematic Evaluation of ATP
Principal Investigator
Electrophysiologist
Protocol Number
IRB:PRO00081920
NCT:NCT02923726
ClinicalTrials.gov
Contact the Duke Recruitment Innovation Center
MyResearchPartners@duke.edu
or
919-681-5698