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B cells in Adult and Children with Lupus - Clinical Trial

What is the Purpose of this Study?

We are doing this study to better understand what causes lupus and how lupus is different in children versus adults. This research study examines the different types of B cells in children and adults with lupus, compared to children and adults without lupus. This might help explain why children with lupus often have more severe symptoms.

What is the Condition Being Studied?

Systemic Lupus Erythematosus (Lupus, or SLE)

Who Can Participate in the Study?

To be in this study, you must:
1. Be between the ages of 11-18 years of age or between the ages of 26-50
2. Have a diagnosis of SLE (Lupus) in the past 10 years
3. Have not received treatment with rituximab or cyclophosphamide within the past 2 years
4. Have not received treatment with belimumab within the past 6 months
5. Not have an active infection or have another rheumatologic diagnosis

Age Group
Adults, Children

What is Involved?

If you agree to join this study, you will have only one study visit where research blood drawn.

Study Details

Full Title
Comparing B Cell Tolerance Checkpoints Between Pediatric-Onset and Adult-Onset Lupus
Principal Investigator
Protocol Number
Contact the Duke Recruitment Innovation Center