The PRiME Study (Brain Cancer) - Clinical Trial
What is the Purpose of this Study?
We are doing this study to learn more about the study vaccine (PEP-CMV) and to understand if it helps the immune system fight brain cancer.
Brain Cancer (World Health Organization Grade III or IV glioma or medulloblastoma)
Who Can Participate in the Study?
Children and adults, 3-35 years old with:
- Grade III or IV glioma that has progressed or recurred
- Medulloblastoma that has progressed or recurred
What is Involved?
If you, or your child, choose to join this study, you or your child will:
- Have a blood test for a common virus called cytomegalovirus (CMV)
- Have standard radiation therapy with temozolomide (a chemotherapy) before study procedures
- Have blood drawn
- Get a Tetanus-diphtheria (Td) vaccine shot (given in the leg)
- Get the study vaccine (PEP-CMV) every 2 weeks for the first 3 vaccines and then once a month
Study Details
