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GENIE study (Overactive Bladder) - Clinical Trial

What is the Purpose of this Study?

We are doing this study is to find out why women with insulin resistance are more likely to get overactive bladder.
What is the Condition Being Studied?
Overactive Bladder with Insulin Resistance

Who Can Participate in the Study?

Women age 18-89 who have at least one of the following:
- Overactive bladder or Urge Urinary Incontinence
- Insulin resistance (including diabetes and pre-diabetes)
- Type 2 Diabetes well controlled
- Both overactive bladder and insulin resistance
- Are healthy without overactive bladder and without insulin resistance

Age Group

What is Involved?

If you choose to join this study, you will:
- Have medical and demographic information collected about you
- Have a visit to confirm if it is safe for you to join the study
-- At this visit you will complete questionnaires and take home a kit to collect urine at home on the morning of the next visit
- Have a morning visit while you are FASTING (no food for 6 hours)
-- You will bring the kit that you took home with you to this visit
- Have another visit to give another urine sample and a blood sample

Study Details

Full Title
Epigenomics in insulin resistance associated overactive bladder
Principal Investigator
Protocol Number
IRB: PRO00079255
NCT: NCT03057158
Phase N/A
Contact the Duke Recruitment Innovation Center