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Alliance A021501 (Pancreatic Cancer) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to compare any good and bad effects of using chemotherapy compared to chemotherapy with radiation before surgery. This study will show us which approach is better, the same, or worse than the other.

What is the Condition Being Studied?

Pancreatic Cancer

Who Can Participate in the Study?

Adults with pancreatic cancer who:
- Have not had chemotherapy or radiation therapy for pancreatic cancer
- Are not pregnant or nursing

Age Group
Adults

What is Involved?

If you choose to join this study, you will:
- Get 8 cycles (1 cycle is equal to 14 days) of chemotherapy before surgery
- Have a scan to see if removing your cancer is appropriate
- Get 4 more cycles of chemotherapy if you have surgery. The cycles will be after your surgery
- Answer questionnaires to see how you are feeling physically and emotionally during your cancer treatment
- Be followed with clinic visits, scans and blood tests for about 5 years from the day you started the surgery after the chemotherapy and surgery are done

Study Details

Full Title
Alliance A021501: Preoperative Extended Chemotherapy versus Chemotherapy Plus Hypofractionated Radiation Therapy for Borderline Resectable Adenocarcinoma of the Head of the Pancreas
Principal Investigator
Medical Oncologist
Protocol Number
IRB:PRO00078527
NCT:NCT02839343
Phase
Phase II
ClinicalTrials.gov
Contact the Duke Recruitment Innovation Center
studyrecruitment@duke.edu
or
919-681-5698