Development of a Novel Transdiagnostic Intervention for Anhedonia - Clinical Trial
What is the Purpose of this Study?
We are doing this study to learn more about a new form of psychotherapy designed to treat anhedonia (difficulty feeling joy or pleasure and low motivation).
Anhedonia is a symptom of many mental conditions including anxiety, depression, PTSD and ADHD.
Anhedonia (difficulty feeling joy or pleasure and low motivation)
Who Can Participate in the Study?
Adults age 18-50 who:
- Are interested in receiving talk therapy for low motivation and difficulty feeling pleasure
- Do not currently take psychiatric medication
- Are not currently in psychotherapy
- Have no history of neurological conditions (for example, stroke, seizure, or concussions)
- Are able to safely have MRI scans (for example, no metal in the body or claustrophobia)
- Have not used antidepressants, antipsychotics or mood stabilizers in the past 4 weeks.
Please contact the study team for more information about participating in the study.
What is Involved?
If you choose to join this study, you will:
- Have a screening visit that may last up to 4 hours
- Have up to 2 fMRIs (magnetic resonance imaging tests) at UNC's Biomedical Research Imaging Center
- Have up to 2 blood draws over the 15 weeks of the study
- Be randomized (like the flip of a coin) to receive one of two kinds of talk therapy
- Be asked to attend one-hour talk therapy sessions once a week at Duke University for 15 weeks
- Be asked to fill out questionnaires about your health and how are feeling up to 5 times over the study
- Be asked to complete computer tasks up to 5 times over the study