Phase I/II Trial of Pre-Op IG-IMPT or IMRT with SIB for Retroperitoneal Sarcomas - Clinical Trial

What is the Purpose of this Study?

We are doing this study to look at the use of IG-IMRT as a treatment for retroperitoneal sarcomas.

What is the Condition Being Studied?

Retroperitoneal Sarcomas

Who Can Participate in the Study?

Adults who:
- Are diagnosed with primary soft tissue sarcoma of the retroperitoneum
- Have a life expectancy of greater than 2 years

Age Group

What is Involved?

If you choose to join this study, you will:
- Undergo radiation therapy using IG-IMRT before surgery for the removal of your tumor.
- Receive a standard dose of radiation that will be given to the majority of the tumor and at the same time, a higher dose of radiation will be given to certain areas of the tumor identified as higher risks.
- Schedule your surgery following radiation therapy with your surgeon.
- Be involved in the study for about 6 months.

Study Details

Full Title
Phase I/II Trial of Pre-Operative Image Guided Intensity Modulated Proton Radiation Therapy (IMPT) or Photon (IMRT) with Simultaneously Integrated Boost to the High Risk Margin for Retroperitoneal Sarcomas
Principal Investigator
General Surgeon
Protocol Number
IRB: PRO00075846
NCT: NCT01659203
Phase I/II
Enrollment Status
Open for Enrollment
Contact the Duke Recruitment Innovation Center