Paracrine Effects on Insulin Secretion - Clinical Trial

We are doing this study to look at the role of a naturally occurring hormone glucagon-like peptide (GLP-1) on insulin secretion and how this hormone helps control blood glucose levels. GLP-1 is released into the circulating blood after eating and helps to control the blood glucose levels by increasing insulin secretion by cells in the pancreas.

Healthy Veterans and glucose control

Veterans who:
- Are 20-45 years old
- Do NOT have diabetes

If you decide to volunteer and participate in the study, you will:
- Have 3 study visits over 3 to 6 weeks
- During Visits 2 and 3 you will:
-- Have an intravenous infusion to measure your blood sugar (glucose) in response to a synthetic peptide of amino acids.

An amino acid is the basic building block of protein. Almost every part of your body is made up of proteins. In the same way, repair, maintenance of cells and critical bio-chemical processes in the body are dependent on proteins.