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Immune Profile Post-Chemotherapy in Gynecologic Cancers - Clinical Trial

What is the Purpose of this Study?

We are doing this study to understand after you get treatment for your cancer what changes happen in the tumor and immune cells.

What is the Condition Being Studied?

Ovarian, Fallopian Tube, Peritoneal, or Uterine Cancer

Who Can Participate in the Study?

Adult women who:
- Are highly suspicious for, or have a confirmed diagnosis of, epithelial ovarian, fallopian tube, primary peritoneal, or high risk endometrial cancer
- Are about to have a diagnostic biopsy or paracentesis/thoracentesis
- Will get chemotherapy before they have surgery

Age Group
Adults

What is Involved?

If you choose to join this study, you will:
- Be asked to allow our surgeons to collect leftover tissue or fluid before you begin chemotherapy and again once you have had a few cycles of chemotherapy
- Be asked to provide a blood sample before chemotherapy treatment, at surgery and after you have completed treatment
- Agree for us to collect clinical data from your medical record related to your diagnosis

Study Details

Full Title
A Pilot Study Investigating the Effect of Chemotherapy on the Tumoral Immunoprofile of Gynecologic Cancers
Principal Investigator
Gynecologic Cancers Specialist
Protocol Number
IRB:PRO00066330
NCT:NCT02824328
Phase
Phase Pilot
ClinicalTrials.gov
Contact the Duke Recruitment Innovation Center
MyResearchPartners@duke.edu
or
919-681-5698