Effects of Exercise on Cartilage Strain - Clinical Trial

What is the Purpose of this Study?

If you choose to join this study, you will:
- Get an MRI of your knee
- Perform a walking or hopping task
- Get another MRI of your knee
- Complete the same imaging and exercise procedure with the other leg
- Complete several questionnaires
- Provide a blood sample

What is the Condition Being Studied?

Anterior cruciate ligament (ACL) deficiency

Who Can Participate in the Study?

Adults who:
- Have acute isolated ACL rupture
- Are healthy volunteers with a normal BMI and no history of any ACL rupture or other knee injury

Age Group

What is Involved?

We are doing this study to better understand how and why osteoarthritis develops after ACL injury.

Study Details

Full Title
Effects of Exercise on Cartilage Strain
Principal Investigator
Louis Defrate
Protocol Number
IRB: PRO00033254
Phase N/A
Enrollment Status
Open for Enrollment
Contact the Duke Recruitment Innovation Center