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CALGB 30610 (Limited Small Cell Lung Cancer) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to compare two different ways to give radiation therapy to see which way is better for patients with small cell lung cancer on standard chemotherapy.

What is the Condition Being Studied?

Limited-stage small cell lung cancer

Who Can Participate in the Study?

Adults with small cell lung cancer who:
- Have not had any radiotherapy
- Have had no more than 1 cycle of chemotherapy
- Have not had surgery to completely remove the lung cancer
- Are not pregnant or nursing

Age Group

What is Involved?

If you choose to join this study, you will:
- Be randomized (like a flip of a coin) to get either:
-- Group 1: The standard amount of radiation therapy twice a day for 3 weeks
-- Group 2: Higher than the standard amount of radiation therapy once a day for 7 weeks
- Continue to have the recommended amount of chemotherapy for small cell lung cancer
- Have CT scans for up to 10 years; every 3 months for the first 2 years, every 6 months for the next 3 years, then yearly for the next 5 years
- Have pulmonary function tests to look at your lung function

Study Details

Full Title
Phase III Comparison of Thoracic Radiotherapy Regimens in Patients with Limited Small Cell Lung Cancer also Receiving Cisplatin or Carboplatin and Etoposide.
Principal Investigator
Medical Oncologist
Protocol Number
Phase III
Contact the Duke Recruitment Innovation Center