Wolfgang B. Liedtke, MD, PhD

Department / Division:
Medicine / Neurology

Address:
DUMC 2900
Durham, NC 27710

Appointment Telephone:
919-668-7600 or 919-668-2891

Office Telephone:
919-684-0058

Fax Telephone:
919-684-6514

• MD, University of Cologne (Germany), 1989

• Neurology, University of Tuebingen (Germany), 1989-1991
• Neurology, University of Essen (Germany), 1991-1993
• Psychiatry, University of Essen (Germany), 1993-1994

• Neuropathology, Albert Einstein College of Medicine of Yeshiva University (New York), 1994-1997
• Fellow, Alexander von Humboldt Foundation (Germany)
• Feodor Lynen Fellow in Neuropathology

• PhD, Clinical Medical Sciences/Medical Virology, University of Bochum (Germany), 1990

Clinical Interests:
Neuropathic pain of trigeminal origin, excluding migraine, but including facial pain, trigeminal neuralgia, and pain of dental, eye, nose, and throat origins

Research Interests:
Research Interests in the Liedtke-Lab:


Pain/ nociception

Sensory transduction and -transmission

TRP ion channels

Water and salt equilibrium regulated by the central nervous system




To visit the lab's website, to down-load papers and Dr. Liedtke's CV

http://neurobiology.mc.duke.edu/CTN/faculty/liedtke/

Representative Publications:
Liedtke W. Transient receptor potential vanilloid channels functioning in transduction of osmotic stimuli. J Endocrinol. 2006 Dec;191(3):515-23. (2006) Abstract

Liedtke W, Kim C. Functionality of the TRPV subfamily of TRP ion channels: add mechano-TRP and osmo-TRP to the lexicon! Cell Mol Life Sci. 2005 Dec;62(24):2985-3001. (2005) Abstract

Liedtke W, Tobin DM, Bargmann CI, Friedman JM. Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2003 Nov 25;100 Suppl 2:14531-6. (2003) Abstract

Liedtke W, Friedman JM. Abnormal osmotic regulation in trpv4-/- mice. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13698-703. (2003) Abstract

Liedtke W, Choe Y, Martí-Renom MA, Bell AM, Denis CS, Sali A, Hudspeth AJ, Friedman JM, Heller S. Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell. 2000 Oct 27;103(3):525-35. (2000) Abstract

Liedtke W. Inadequate antidiuretic hormone secretion after sagittal sinus thrombosis caused by protein S deficiency. Stroke. 1991 Jun;22(6):819. (1991) Abstract