Physicians

Departments / Divisions

• Medicine / Medicine-Neurology
• Neurobiology

Address
DUMC 2900
Durham, NC 27710

Appointment Telephone
919-668-7600, 919-668-2891

Office Telephone
919-684-0058

Fax Telephone
919-684-6514

Training

• MD, University of Cologne (Germany), 1989

Residency

• Neurology, University of Tuebingen (Germany), 1989-1991
• Neurology, University Hospital of Essen (Germany), 1991-1993
• Psychiatry, University Hospital of Essen and State Hospital for Psychiatric Care, Essen (Germany), 1993-1994

Fellowship

• Neuropathology, Albert Einstein College of Medicine of Yeshiva University (New York), 1994-1997
• Fellow, Alexander von Humboldt Foundation (Germany)
• Feodor Lynen Fellow in Neuropathology

Other Training

• PhD, Clinical Medical Sciences/Medical Virology, University of Bochum (Germany), 1990

Clinical Interests
Neuropathic pain of trigeminal origin, excluding migraine, but including facial pain, trigeminal neuralgia, and pain of dental, eye, nose, and throat origins

Research Interests
Research Interests in the Liedtke-Lab:


Pain/ nociception

Sensory transduction and -transmission

TRP ion channels

Water and salt equilibrium regulated by the central nervous system




To visit the lab's website, to down-load papers and Dr. Liedtke's CV

http://neurobiology.mc.duke.edu/CTN/faculty/liedtke/

Industry Relationships and Collaborations (What's this?)

This physician has no reported relationships with industry.

Representative Publications
Liedtke W. Transient receptor potential vanilloid channels functioning in transduction of osmotic stimuli. J Endocrinol. 2006 Dec;191(3):515-23. (2006) Abstract

Liedtke W, Kim C. Functionality of the TRPV subfamily of TRP ion channels: add mechano-TRP and osmo-TRP to the lexicon! Cell Mol Life Sci. 2005 Dec;62(24):2985-3001. (2005) Abstract

Liedtke W, Friedman JM. Abnormal osmotic regulation in trpv4-/- mice. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13698-703. (2003) Abstract

Liedtke W, Tobin DM, Bargmann CI, Friedman JM. Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2003 Nov 25;100 Suppl 2:14531-6. (2003) Abstract

Liedtke W, Choe Y, Martí-Renom MA, Bell AM, Denis CS, Sali A, Hudspeth AJ, Friedman JM, Heller S. Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell. 2000 Oct 27;103(3):525-35. (2000) Abstract

Liedtke W. Inadequate antidiuretic hormone secretion after sagittal sinus thrombosis caused by protein S deficiency. Stroke. 1991 Jun;22(6):819. (1991) Abstract