Director, Pediatric Blood and Marrow Transplant Fellowship Program
Department / Division
Pediatrics / Pediatric-Blood & Marrow Transplantation
Durham, NC 27710
Cord-blood, stem-cell, and bone-marrow transplant for childhood cancers; inherited metabolic disorders; immunodeficiency; hemoglobinopathies and other serious diseases; histocompatibility (tissue typing) and other determinants of alloreactivity, with a focus on identifying the best-matched donors by using cutting-edge molecular techniques; post-transplant viral infections, with a focus on early detection and treatment
1. Expanding the role of umbilical cord blood transplants for inherited metabolic disorders.
2. Impact of histocompatibility and other determinants of alloreactivity on clinical outcomes of unrelated cord blood transplants.
3. Studies to analyse the impact of Killer Immunoglobulin receptors on the outcomes of hematopoietic stem cell transplantation utilizing haploidentical, CD34 selected, familial grafts.
4. Propective longitudinal study of serial monitoring of adenovirus in allogenic transpants(SMAART)patients.
5. Use of mesenchymal stem cells for the treatment of GVHD
This faculty member has no reported relationships with industry.
Boelens, JJ; Rocha, V; Aldenhoven, M; Wynn, R; O'Meara, A; Michel, G; Ionescu, I; Parikh, S; Prasad, VK; Szabolcs, P; Escolar, M; Gluckman, E; Cavazzana-Calvo, M; Kurtzberg, J; EUROCORD, Inborn error Working Party of EBMT and Duke University. Risk factor analysis of outcomes after unrelated cord blood transplantation in patients with hurler syndrome. Biology of Blood and Marrow Transplantation. 2009;15:618-625. (2009) Abstract
Parikh, SH; Mendizabal, A; Martin, PL; Prasad, VK; Szabolcs, P; Driscoll, TA; Kurtzberg, J. Unrelated donor umbilical cord blood transplantation in pediatric myelodysplastic syndrome: a single-center experience. Biology of Blood and Marrow Transplantation. 2009;15:948-955. (2009) Abstract
Hollingsworth, CL; Frush, DP; Kurtzburg, J; Prasad, VK. Pediatric hematopoietic stem cell transplantation and the role of imaging. Radiology. 2008;248:348-365. (2008) Abstract
Kurtzberg, J; Prasad, VK; Carter, SL; Wagner, JE; Baxter-Lowe, LA; Wall, D; Kapoor, N; Guinan, EC; Feig, SA; Wagner, EL; Kernan, NA; COBLT Steering Committee. Results of the Cord Blood Transplantation Study (COBLT): clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies. Blood. 2008;112:4318-4327. (2008) Abstract
Page, KM; Mendizabal, AM; Prasad, VK; Martin, PL; Parikh, S; Wood, S; Sempowski, GD; Szabolcs, P; Kurtzberg, J. Posttransplant autoimmune hemolytic anemia and other autoimmune cytopenias are increased in very young infants undergoing unrelated donor umbilical cord blood transplantation. Biology of Blood and Marrow Transplantation. 2008;14:1108-1117. (2008) Abstract
Prasad, VK; Kurtzberg, J. Emerging trends in transplantation of inherited metabolic diseases. Bone Marrow Transplantation. 2008;41:99-108. (2008) Abstract
Prasad, VK; Mendizabal, A; Parikh, SH; Szabolcs, P; Driscoll, TA; Page, K; Lakshminarayanan, S; Allison, J; Wood, S; Semmel, D; Escolar, ML; Martin, PL; Carter, S; Kurtzberg, J. Unrelated donor umbilical cord blood transplantation for inherited metabolic disorders in 159 pediatric patients from a single center: influence of cellular composition of the graft on transplantation outcomes. Blood. 2008;112:2979-2989. (2008) Abstract
Beam, D; Poe, MD; Provenzale, JM; Szabolcs, P; Martin, PL; Prasad, V; Parikh, S; Driscoll, T; Mukundan, S; Kurtzberg, J; Escolar, ML. Outcomes of unrelated umbilical cord blood transplantation for X-linked adrenoleukodystrophy. Biology of Blood and Marrow Transplantation. 2007;13:665-674. (2007) Abstract
Parikh, SH; Szabolcs, P; Prasad, VK; Lakshminarayanan, S; Martin, PL; Driscoll, TA; Kurtzberg, J. Correction of chronic granulomatous disease after second unrelated-donor umbilical cord blood transplantation. Pediatric Blood and Cancer. 2007;49:982-984. (2007) Abstract
Seo, SK; Regan, A; Cihlar, T; Lin, DC; Boulad, F; George, D; Prasad, VK; Kiehn, TE; Polsky, B. Cytomegalovirus ventriculoencephalitis in a bone marrow transplant recipient receiving antiviral maintenance: clinical and molecular evidence of drug resistance. Clinical Infectious Diseases. 2001;33:e105-e108. (2001) Abstract
Antunes, NL; Boulad, F; Prasad, V; Rosenblum, M; Lis, E; Souweidane, M. Rolandic encephalopathy and epilepsia partialis continua following bone marrow transplant. Bone Marrow Transplantation. 2000;26:917-919. (2000) Abstract
Boulad, F; Gillio, A; Small, TN; George, D; Prasad, V; Torok-Castanza, J; Regan, AD; Collins, N; Auerbach, AD; Kernan, NA; O'Reilly, RJ. Stem cell transplantation for the treatment of Fanconi anaemia using a fludarabine-based cytoreductive regimen and T-cell-depleted related HLA-mismatched peripheral blood stem cell grafts. British Journal of Haematology. 2000;111:1153-1157. (2000) Abstract
Prasad, VK; Heller, G; Kernan, NA; O'Reilly, RJ; Yang, SY. The probability of HLA-C matching between patient and unrelated donor at the molecular level: estimations based on the linkage disequilibrium between DNA typed HLA-B and HLA-C alleles. Transplantation. 1999;68:1044-1050. (1999) Abstract
Prasad, VK; Kernan, NA; Heller, G; O'Reilly, RJ; Yang, SY. DNA typing for HLA-A and HLA-B identifies disparities between patients and unrelated donors matched by HLA-A and HLA-B serology and HLA-DRB1. Blood. 1999;93:399-409. (1999) Abstract
Prasad, VK; Kernan, NA; Heller, G; O'Reilly, RJ; Yang, SY. HLA-C disparity between patients and unrelated donors matched for HLA-A, -B, and -DRB1 alleles: impact of serological vs. DNA typing for HLA-A and -B loci. Biology of Blood and Marrow Transplantation. 1999;5:77-85. (1999) Abstract
Prasad, VK; Kim, IK; Farrington, K; Bussel, JB. TTP following ITP in an HIV-positive boy. Journal of Pediatric Hematology/Oncology. 1996;18:384-386. (1996) Abstract
Prasad, VK; Lewis, IJ; Aparicio, SR; Heney, D; Hale, JP; Bailey, CC; Kinsey, SE. Progressive glomerular toxicity of ifosfamide in children. Pediatric Blood and Cancer. 1996;27:149-155. (1996) Abstract
Prasad, VK; Yang, SY. Allele assignment for HLA-A, -B, and -C genes to the Tenth International Histocompatibility Workshop cell lines. Tissue Antigens: immune response genetics. 1996;47:538-546. (1996) Abstract
Prasad, VK; Aronson, DC; Gerald, WL; Meyers, PA; La Quaglia, MP. Hepatic focal nodular hyperplasia in infant antenatally exposed to steroids. Lancet. 1995;346:371. (1995) Abstract
McClure, RJ; Prasad, VK; Brocklebank, JT. Treatment of hyperkalaemia using intravenous and nebulised salbutamol. Archives of Disease in Childhood. 1994;70:126-128. (1994) Abstract
Prasad, VK; Corlett, SA; Abaasi, K; Heney, D; Lewis, I; Chrystyn, H. Ifosfamide enantiomers: pharmacokinetics in children. Cancer Chemotherapy and Pharmacology. 1994;34:447-449. (1994) Abstract
Kumar, H; Aneja, S; Prasad, VK; Arora, SK; Mullick, DN. Tetanus neonatorum: clinico-epidemiological profile. Indian Pediatrics. 1988;25:1054-1057. (1988) Abstract