Department / Division
Pathology /
Pathology Clinical Services
Address
DUMC 3712
Durham, NC 27710
Office Telephone
919-668-5440
Fax Telephone
919-681-1658
Clinical Interests
Asbestos-related diseases, pneumonoconiosis, pulmonary pathology, analytical
electron microscopy
Research Interests
My laboratory continues its interest in analyzing lung tissue for its asbestos content and correlating these results with pathologic diagnoses and with exposure histories. Both concentrations of asbestos fibers and types of fibers present are determined by a combination of light microscopy and scanning electron microscopy equipped with an energy dispersive spectrometer. Studies are also performed on lung tissue from individuals with other types of occupational exposures, such as coal dust and silica. This primarily involves in situ analysis of particulates in tissue sections using a combination of scanning electron microscopy, back scattered electron imaging, and energy dispersive x-ray analysis. Similar technology is used to analyze urinary calculi and xenobiotics within tissue samples, such as silicone in breast implant capsules.
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This physician has no reported relationships with industry.
Representative Publications
Roggli VL, Oury TD, Sporn TA, eds. Pathology of Asbestos-Associated Diseases, 2nd Ed., Springer: New York, 2004.
(2004)
Butnor KJ, Sporn TA, Ingram P, Gunasegaram S, Pinto JF, Roggli VL: Beryllium detection in human lung tissue using electron probe x-ray microanalysis. Mod. Pathol. 16: 1171-1177, 2003.
(2003)
Butnor KJ, Sporn TA, Roggli VL: Exposure to brake dust and malignant mesothelioma: A study of 10 cases with mineral fiber analyses. Ann. Occup. Hyg. 47: 325-330, 2003.
(2003)
Roggli, V.L., Sharma, A., Butnor, K.J., Sporn, T., and Vollmer, R.T.: Malignant mesothelioma and occupational exposure to asbestos: A clinicopathological correlation of 1445 cases. Ultrastruct. Pathol. 26: 55-65, 2002.
(2002)
Roggli, V.L., Vollmer, R.T., Butnor, K.J., and Sporn, T.A.: Tremolite and mesothelioma. Ann. Occup. Hyg. 46: 447-453, 2002.
(2002)
Roggli VL, Sanders LL: Asbestos content of lung tissue and carcinoma of the lung: A clinicopathologic correlation and mineral fiber analysis of 234 cases. Ann Occup Hyg 44: 109-117, 2000.
(2000)
