Department / Division:
Pathology

Address:
DUMC 3712
Durham, NC 27710

Office Telephone:
919-668-5440

Fax Telephone:
919-681-1658

• MD, Baylor College of Medicine (Texas), 1976

• Pathology, Baylor Affiliated Hospitals (Texas), 1976-1980
• Pathology, Duke University Medical Center, 1980-1981

Clinical Interests:
Asbestos-related diseases, pneumonoconiosis, pulmonary pathology, analytical electron microscopy

Research Interests:
My laboratory continues its interest in analyzing lung tissue for its asbestos content and correlating these results with pathologic diagnoses and with exposure histories.  Both concentrations of asbestos fibers and types of fibers present are determined by a combination of light microscopy and scanning electron microscopy equipped with an energy dispersive spectrometer.  Studies are also performed on lung tissue from individuals with other types of occupational exposures, such as coal dust and silica.  This primarily involves in situ analysis of particulates in tissue sections using a combination of scanning electron microscopy, back scattered electron imaging, and energy dispersive x-ray analysis.  Similar technology is used to analyze urinary calculi and xenobiotics within tissue samples, such as silicone in breast implant capsules.
.

Representative Publications:
Roggli VL, Oury TD, Sporn TA, eds. Pathology of Asbestos-Associated Diseases, 2nd Ed., Springer: New York, 2004. (2004)

Butnor KJ, Sporn TA, Roggli VL: Exposure to brake dust and malignant mesothelioma: A study of 10 cases with mineral fiber analyses. Ann. Occup. Hyg. 47: 325-330, 2003. (2003)

Butnor KJ, Sporn TA, Ingram P, Gunasegaram S, Pinto JF, Roggli VL: Beryllium detection in human lung tissue using electron probe x-ray microanalysis. Mod. Pathol. 16: 1171-1177, 2003. (2003)

Roggli, V.L., Vollmer, R.T., Butnor, K.J., and Sporn, T.A.: Tremolite and mesothelioma.  Ann. Occup. Hyg. 46: 447-453, 2002. (2002)

Roggli, V.L., Sharma, A., Butnor, K.J., Sporn, T., and Vollmer, R.T.: Malignant mesothelioma and occupational exposure to asbestos: A clinicopathological correlation of 1445 cases.  Ultrastruct. Pathol. 26: 55-65, 2002. (2002)

Roggli VL, Sanders LL:  Asbestos content of lung tissue and carcinoma of the lung:  A clinicopathologic correlation and mineral fiber analysis of 234 cases.  Ann Occup Hyg 44: 109-117, 2000. (2000)