Department / Division
Medicine / Medicine-Pulmonary
Durham, NC 27710
Evaluation for pulmonary hypertension, pulmonary thromboembolic disease, chronic thromboembolic pulmonary hypertension (CTEPH)
Both clinical research and patient care involves venous thromboembolic disease, and endstage lung disease. The latter population includes primary and secondary pulmonary hypertension, severe emphysema (lung volume reduction surgery candidates) and all patients evaluated for lung transplantation. Lung transplant clinical research focuses more heavily on the posttransplant setting. Dr. Tapson is collaborating with basic science laboratories but not conducting basic research himself.
Specific research approaches:
The approaches utilized are single or multicenter clinical trials involving prevention and treatment of venous thromboembolism, diagnostic approaches to deep venous thrombosis and pulmonary embolism, pharmacologic therapy for pulmonary hypertension, and immunosuppressive and antiinfective therapy for lung transplant patients. Dr. Tapson has collaborated extensively with radiology in evaluating patients with venous thromboembolic disease and after lung transplantation, particularly with regard to evolving technology such as spiral computed tomography and magnetic resonance imaging. Goals include establishing database for lung transplant and pulmonary hypertension patients (in progress), and continuing outcomes research.
Areas of expertise/national recognition:
These include venous thromboembolism, lung transplantation, and pulmonary hypertension (see committees). Dr. Tapson currently serves as on both the American Thoracic Society and American College of Chest Physicians consensus panels for venous thromboembolism, and has published a book on this topic. He has been invited to write a number of reviews on this topic and is completing a book chapter on pulmonary embolism for the Cecil Textbook of Medicine. He was invited to Edinborough, Scotland last year to give the Sydney Watson Smith Memorial Lecture for the Royal College of Physicians (New Diagnostic and Therapeutic Modalities for Venous Thromboembolism). He will chair two sessions on this topic at the American Thoracic Society Meeting in Chicago this year.
Venous thromboembolism Low molecular weight heparin
Pulmonary embolism Lung transplantation
Deep venous thrombosis Immunosuppressive therapy
Magnetic resonance imaging Lung volume reduction surgery
This faculty member has no reported relationships with industry.