Physicians

Acting Chief, Division of Nuclear Medicine

Department / Division
Radiology / Nuclear Medicine

Address
DUMC 3949
Durham, NC 27710

Appointment Telephone
919-684-7647

Office Telephone
919-684-7631

Fax Telephone
919-684-7167

Training

• MD, Dartmouth Medical School (New Hampshire), 1990

Residency

• Internal Medicine, Dartmouth-Hitchcock Medical Center (New Hampshire), 1990-1991
• Diagnostic Radiology, Deaconess Hospital (Massachusetts), 1992-1996

Fellowship

• Nuclear Radiology, Deaconess Hospital (Massachusetts), 1995-1996
• Cross-Sectional Imaging, Beth Israel Deaconess Medical Center (Massachusetts), 1996-1997
• Interventional-Intraoperative MRI, Brigham and Women's Hospital (Massachusetts), 1997-1998

Other Training

• PhD, Engineering Sciences, Dartmouth College (New Hampshire), 1990

Clinical Interests
Oncologic imaging, PET/CT, image processing, radiation therapy treatment planning, radionuclide therapy

Research Interests
1. Oncologic Imaging: PET/CT, novel PET radiotracers

2. Radionuclide therapy of cancer, Radiation Therapy Planning

3. Image-guided radiation therapy treatment planning

4. Hyperthermia

Industry Relationships and Collaborations (What's this?)

This faculty member has no reported relationships with industry.

Representative Publications
Ma, J; Zhang, J; Zhou, S; Hubbs, JL; Foltz, RJ; Hollis, DR; Light, KL; Wong, TZ; Kelsey, CR; Marks, LB. Regional lung density changes after radiation therapy for tumors in and around thorax. International Journal of Radiation: Oncology - Biology - Physics. 2010;76:116-122. (2010) Abstract

Brady, MJ; Thomas, J; Wong, TZ; Franklin, KM; Ho, LM; Paulson, EK. Adrenal nodules at FDG PET/CT in patients known to have or suspected of having lung cancer: a proposal for an efficient diagnostic algorithm. Radiology. 2009;250:523-530. (2009) Abstract

Craciunescu, OI; Blackwell, KL; Jones, EL; Macfall, JR; Yu, D; Vujaskovic, Z; Wong, TZ; Liotcheva, V; Rosen, EL; Prosnitz, LR; Samulski, TV; Dewhirst, MW. DCE-MRI parameters have potential to predict response of locally advanced breast cancer patients to neoadjuvant chemotherapy and hyperthermia: a pilot study. International Journal of Hyperthermia. 2009;25:405-415. (2009) Abstract

Craciunescu, OI; Stauffer, PR; Soher, BJ; Wyatt, CR; Arabe, O; Maccarini, P; Das, SK; Cheng, KS; Wong, TZ; Jones, EL; Dewhirst, MW; Vujaskovic, Z; MacFall, JR. Accuracy of real time noninvasive temperature measurements using magnetic resonance thermal imaging in patients treated for high grade extremity soft tissue sarcomas. Medical Physics. 2009;36:4848-4858. (2009) Abstract

Kimura, M; Tsivian, M; Mouraviev, V; Mayes, JM; Price, MM; Bannister, MC; Madden, JF; Wong, TZ; Polascik, TJ. Utilization of (111)In-Capromab pendetide SPECT-CT for detecting seminal vesicle invasion with recurrent prostate cancer after primary in situ therapy. International Journal of Urology. 2009;16:971-975. (2009) Abstract

Ma, J; Zhang, J; Zhou, S; Hubbs, JL; Foltz, RJ; Hollis, DR; Light, KL; Wong, TZ; Kelsey, CR; Marks, LB. Association between RT-induced changes in lung tissue density and global lung function. International Journal of Radiation: Oncology - Biology - Physics. 2009;74:781-789. (2009) Abstract

Willett, CG; Duda, DG; di Tomaso, E; Boucher, Y; Ancukiewicz, M; Sahani, DV; Lahdenranta, J; Chung, DC; Fischman, AJ; Lauwers, GY; Shellito, P; Czito, BG; Wong, TZ; Paulson, E; Poleski, M; Vujaskovic, Z; Bentley, R; Chen, HX; Clark, JW; Jain, RK. Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study. Journal of Clinical Oncology. 2009;27:3020-3026. (2009) Abstract

Agress, H; Wong, TZ; Shreve, P. Interpretation and reporting of positron emission tomography-computed tomographic scans. Seminars in Ultrasound, CT and MRI. 2008;29:283-290. (2008) Abstract

Bunyaviroch, T; Turkington, TG; Wong, TZ; Wilson, JW; Colsher, JG; Coleman, RE. Quantitative effects of contrast enhanced CT attenuation correction on PET SUV measurements. Molecular Imaging and Biology. 2008;10:107-113. (2008) Abstract

Ho, LM; Paulson, EK; Brady, MJ; Wong, TZ; Schindera, ST. Lipid-poor adenomas on unenhanced CT: does histogram analysis increase sensitivity compared with a mean attenuation threshold?. American Journal of Roentgenology. 2008;191:234-238. (2008) Abstract

Koontz, BF; Mouraviev, V; Johnson, JL; Mayes, J; Chen, SH; Wong, TZ; Anscher, MS; Sun, L; Moul, J; Polascik, TJ. Use of local (111)in-capromab pendetide scan results to predict outcome after salvage radiotherapy for prostate cancer. International Journal of Radiation: Oncology - Biology - Physics. 2008;71:358-361. (2008) Abstract

Reardon, DA; Zalutsky, MR; Akabani, G; Coleman, RE; Friedman, AH; Herndon, JE; McLendon, RE; Pegram, CN; Quinn, JA; Rich, JN; Vredenburgh, JJ; Desjardins, A; Guruangan, S; Boulton, S; Raynor, RH; Dowell, JM; Wong, TZ; Zhao, XG; Friedman, HS; Bigner, DD. A pilot study: 131I-antitenascin monoclonal antibody 81c6 to deliver a 44-Gy resection cavity boost. Neuro-Oncology. 2008;10:182-189. (2008) Abstract

Sampson, JH; Akabani, G; Archer, GE; Berger, MS; Coleman, RE; Friedman, AH; Friedman, HS; Greer, K; Herndon, JE; Kunwar, S; McLendon, RE; Paolino, A; Petry, NA; Provenzale, JM; Reardon, DA; Wong, TZ; Zalutsky, MR; Pastan, I; Bigner, DD. Intracerebral infusion of an EGFR-targeted toxin in recurrent malignant brain tumors. Neuro-Oncology. 2008;10:320-329. (2008) Abstract

Wong, TZ; Jain, MK; Spratt, SE. I-131, I-123, and F-18 FDG-PET imaging in a patient with diffuse sclerosing variant of papillary thyroid cancer. Clinical Nuclear Medicine. 2008;33:834-837. (2008) Abstract

Wong, TZ; Lacy, JL; Petry, NA; Hawk, TC; Sporn, TA; Dewhirst, MW; Vlahovic, G. PET of hypoxia and perfusion with 62Cu-ATSM and 62Cu-PTSM using a 62Zn/62Cu generator. American Journal of Roentgenology. 2008;190:427-432. (2008) Abstract

Zalutsky, MR; Reardon, DA; Akabani, G; Coleman, RE; Friedman, AH; Friedman, HS; McLendon, RE; Wong, TZ; Bigner, DD. Clinical experience with alpha-particle emitting 211At: treatment of recurrent brain tumor patients with 211At-labeled chimeric antitenascin monoclonal antibody 81C6. Journal of Nuclear Medicine. 2008;49:30-38. (2008) Abstract

Mao, J; Zhang, J; Zhou, S; Das, S; Hollis, DR; Folz, RJ; Wong, TZ; Marks, LB. Updated assessment of the six-minute walk test as predictor of acute radiation-induced pneumonitis. International Journal of Radiation: Oncology - Biology - Physics. 2007;67:759-767. (2007) Abstract

Prosnitz, RG; Hubbs, JL; Evans, ES; Zhou, SM; Yu, X; Blazing, MA; Hollis, DR; Tisch, A; Wong, TZ; Borges-Neto, S; Hardenbergh, PH; Marks, LB. Prospective assessment of radiotherapy-associated cardiac toxicity in breast cancer patients: analysis of data 3 to 6 years after treatment. Cancer. 2007;110:1840-1850. (2007) Abstract

Willett, CG; Duda, DG; di Tomaso, E; Boucher, Y; Czito, BG; Vujaskovic, Z; Vlahovic, G; Bendell, J; Cohen, KS; Hurwitz, HI; Bentley, R; Lauwers, GY; Poleski, M; Wong, TZ; Paulson, E; Ludwig, KA; Jain, RK. Complete pathological response to bevacizumab and chemoradiation in advanced rectal cancer. Nature Clinical Practice Oncology. 2007;4:316-321. (2007) Abstract

Wong, TZ; Paulson, EK; Nelson, RC; Patz, EF; Coleman, RE. Practical approach to diagnostic CT combined with PET. American Journal of Roentgenology. 2007;188:622-629. (2007) Abstract

Yamamoto, Y; Wong, TZ; Turkington, TG; Hawk, TC; Coleman, RE. Head and neck cancer: dedicated FDG PET/CT protocol for detection--phantom and initial clinical studies. Radiology. 2007;244:263-272. (2007) Abstract

Evans, ES; Prosnitz, RG; Yu, X; Zhou, SM; Hollis, DR; Wong, TZ; Light, KL; Hardenbergh, PH; Blazing, MA; Marks, LB. Impact of patient-specific factors, irradiated left ventricular volume, and treatment set-up errors on the development of myocardial perfusion defects after radiation therapy for left-sided breast cancer. International Journal of Radiation: Oncology - Biology - Physics. 2006;66:1125-1134. (2006) Abstract

Kleiter, MM; Yu, D; Mohammadian, LA; Niehaus, N; Spasojevic, I; Sanders, L; Viglianti, BL; Yarmolenko, PS; Hauck, M; Petry, NA; Wong, TZ; Dewhirst, MW; Thrall, DE. A tracer dose of technetium-99m-labeled liposomes can estimate the effect of hyperthermia on intratumoral doxil extravasation. Clinical Cancer Research. 2006;12:6800-6807. (2006) Abstract

Reardon, DA; Akabani, G; Coleman, RE; Friedman, AH; Friedman, HS; Herndon, JE; McLendon, RE; Pegram, CN; Provenzale, JM; Quinn, JA; Rich, JN; Vredenburgh, JJ; Desjardins, A; Gururangan, S; Badruddoja, M; Dowell, JM; Wong, TZ; Zhao, XG; Zalutsky, MR; Bigner, DD. Salvage radioimmunotherapy with murine iodine-131-labeled antitenascin monoclonal antibody 81C6 for patients with recurrent primary and metastatic malignant brain tumors: phase II study results. Journal of Clinical Oncology. 2006;24:115-122. (2006) Abstract

Reardon, DA; Quinn, JA; Akabani, G; Coleman, RE; Friedman, AH; Friedman, HS; Herndon, JE; McLendon, RE; Pegram, CN; Provenzale, JM; Dowell, JM; Rich, JN; Vredenburgh, JJ; Desjardins, A; Sampson, JH; Gururangan, S; Wong, TZ; Badruddoja, MA; Zhao, XG; Bigner, DD; Zalutsky, MR. Novel human IgG2b/murine chimeric antitenascin monoclonal antibody construct radiolabeled with 131I and administered into the surgically created resection cavity of patients with malignant glioma: phase I trial results. Journal of Nuclear Medicine. 2006;47:912-918. (2006) Abstract

Yamamoto, Y; Wong, TZ; Turkington, TG; Hawk, TC; Reardon, DA; Coleman, RE. 3'-Deoxy-3'-[F-18]fluorothymidine positron emission tomography in patients with recurrent glioblastoma multiforme: comparison with Gd-DTPA enhanced magnetic resonance imaging. Molecular Imaging and Biology. 2006;8:340-347. (2006) Abstract