Department / Division
Pediatrics /
Pediatric-Blood & Marrow Transplantation
Address
DUMC 3350
Durham, NC 27710
Appointment Telephone
919-668-1100
Office Telephone
919-668-1121
Fax Telephone
919-668-1180
Clinical Interests
Stem-cell (cord blood, peripheral blood, bone marrow) transplantation for hemoglobinopathies such as sickle-cell disease and thalassemia; inherited metabolic disorders, immune disorders, and childhood malignancies; reduced-intensity transplantation for non-malignant diseases
Research Interests
Stem cell transplantation for a variety of disorders - ranging from malignant diseases such as leukemia, lymphoma and myelodysplastic syndrome to nonmalignant diseases such as sickle cell disease, thalassemias, aplastic anemia, histiocytosis and leukodystrophies. My clinical research interest is stem cell transplantation for children with hemoglobinopathies such as sickle cell anemia,thalassemia and other non-malignant disorders. In addition,I am interested in developing startegies, such as reduced intensity conditioning, to make transplant safer.
This faculty member has no reported relationships with industry.
Representative Publications
Kanda, J; Kaynar, L; Kanda, Y; Prasad, VK; Parikh, SH; Lan, L; Shen, T; Rizzieri, DA; Long, GD; Sullivan, KM; Gasparetto, C; Chute, JP; Morris, A; Winkel, S; McPherson, J; Kurtzberg, J; Chao, NJ; Horwitz, ME. Pre-engraftment syndrome after myeloablative dual umbilical cord blood transplantation: risk factors and response to treatment. Bone Marrow Transplantation. 2013;
(2013)
Abstract
Heimall, J; Keller, M; Saltzman, R; Bunin, N; McDonald-McGinn, D; Zakai, E; de Villartay, JP; Moshous, D; Ariue, B; McCarthy, EA; Devlin, BH; Parikh, S; Buckley, RH; Markert, ML. Diagnosis of 22q11.2 deletion syndrome and artemis deficiency in two children with T-B-NK+ immunodeficiency. Journal of Clinical Immunology. 2012;32:1141-1144.
(2012)
Abstract
Kamani, NR; Walters, MC; Carter, S; Aquino, V; Brochstein, JA; Chaudhury, S; Eapen, M; Freed, BM; Grimley, M; Levine, JE; Logan, B; Moore, T; Panepinto, J; Parikh, S; Pulsipher, MA; Sande, J; Schultz, KR; Spellman, S; Shenoy, S. Unrelated donor cord blood transplantation for children with severe sickle cell disease: results of one cohort from the phase II study from the Blood and Marrow Transplant Clinical Trials Network (BMT CTN). Biology of Blood and Marrow Transplantation. 2012;18:1265-1272.
(2012)
Abstract
Parikh, S; Szabolcs, P. Reduced-intensity conditioning (RIC) in children with nonmalignant disorders (NMD) undergoing unrelated donor umbilical cord blood transplantation (UCBT). Biology of Blood and Marrow Transplantation. 2012;18:S53-S55.
(2012)
Abstract
Tewari, P; Martin, PL; Mendizabal, A; Parikh, SH; Page, KM; Driscoll, TA; Malech, HL; Kurtzberg, J; Prasad, VK. Myeloablative transplantation using either cord blood or bone marrow leads to immune recovery, high long-term donor chimerism and excellent survival in chronic granulomatous disease. Biology of Blood and Marrow Transplantation. 2012;18:1368-1377.
(2012)
Abstract
Peters, C; Cornish, JM; Parikh, SH; Kurtzberg, J. Stem cell source and outcome after hematopoietic stem cell transplantation (HSCT) in children and adolescents with acute leukemia. Pediatric Clinics of North America. 2010;57:27-46.
(2010)
Abstract
Boelens, JJ; Rocha, V; Aldenhoven, M; Wynn, R; O'Meara, A; Michel, G; Ionescu, I; Parikh, S; Prasad, VK; Szabolcs, P; Escolar, M; Gluckman, E; Cavazzana-Calvo, M; Kurtzberg, J; EUROCORD, Inborn error Working Party of EBMT and Duke University. Risk factor analysis of outcomes after unrelated cord blood transplantation in patients with hurler syndrome. Biology of Blood and Marrow Transplantation. 2009;15:618-625.
(2009)
Abstract
Parikh, SH; Mendizabal, A; Martin, PL; Prasad, VK; Szabolcs, P; Driscoll, TA; Kurtzberg, J. Unrelated donor umbilical cord blood transplantation in pediatric myelodysplastic syndrome: a single-center experience. Biology of Blood and Marrow Transplantation. 2009;15:948-955.
(2009)
Abstract
Page, KM; Mendizabal, AM; Prasad, VK; Martin, PL; Parikh, S; Wood, S; Sempowski, GD; Szabolcs, P; Kurtzberg, J. Posttransplant autoimmune hemolytic anemia and other autoimmune cytopenias are increased in very young infants undergoing unrelated donor umbilical cord blood transplantation. Biology of Blood and Marrow Transplantation. 2008;14:1108-1117.
(2008)
Abstract
Porkka, K; Koskenvesa, P; Lundán, T; Rimpiläinen, J; Mustjoki, S; Smykla, R; Wild, R; Luo, R; Arnan, M; Brethon, B; Eccersley, L; Hjorth-Hansen, H; Höglund, M; Klamova, H; Knutsen, H; Parikh, S; Raffoux, E; Gruber, F; Brito-Babapulle, F; Dombret, H; Duarte, RF; Elonen, E; Paquette, R; Zwaan, CM; Lee, FY. Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia. Blood. 2008;112:1005-1012.
(2008)
Abstract
Prasad, VK; Mendizabal, A; Parikh, SH; Szabolcs, P; Driscoll, TA; Page, K; Lakshminarayanan, S; Allison, J; Wood, S; Semmel, D; Escolar, ML; Martin, PL; Carter, S; Kurtzberg, J. Unrelated donor umbilical cord blood transplantation for inherited metabolic disorders in 159 pediatric patients from a single center: influence of cellular composition of the graft on transplantation outcomes. Blood. 2008;112:2979-2989.
(2008)
Abstract
Beam, D; Poe, MD; Provenzale, JM; Szabolcs, P; Martin, PL; Prasad, V; Parikh, S; Driscoll, T; Mukundan, S; Kurtzberg, J; Escolar, ML. Outcomes of unrelated umbilical cord blood transplantation for X-linked adrenoleukodystrophy. Biology of Blood and Marrow Transplantation. 2007;13:665-674.
(2007)
Abstract
Parikh, SH; Szabolcs, P; Prasad, VK; Lakshminarayanan, S; Martin, PL; Driscoll, TA; Kurtzberg, J. Correction of chronic granulomatous disease after second unrelated-donor umbilical cord blood transplantation. Pediatric Blood and Cancer. 2007;49:982-984.
(2007)
Abstract
Li, XN; Parikh, S; Shu, Q; Jung, HL; Chow, CW; Perlaky, L; Leung, HC; Su, J; Blaney, S; Lau, CC. Phenylbutyrate and phenylacetate induce differentiation and inhibit proliferation of human medulloblastoma cells. Clinical Cancer Research. 2004;10:1150-1159.
(2004)
Abstract
Parikh, SH; Chintagumpala, M; Hicks, MJ; Trautwein, LM; Blaney, S; Minifee, P; Woo, SY. Clear cell sarcoma of the kidney: an unusual presentation and review of the literature. Journal of Pediatric Hematology/Oncology. 1998;20:165-168.
(1998)
Abstract
Parikh, S; Bharucha, B; Kamdar, S; Kshirsagar, N. Polymorphonuclear leukocyte functions in children with cyanotic and acyanotic congenital heart disease. Indian Pediatrics. 1993;30:883-890.
(1993)
Abstract
