Physicians

Department / Division
Pediatrics / Pediatric-Blood & Marrow Transplantation

Address
DUMC 3350
Durham, NC 27710

Appointment Telephone
919-668-1100

Office Telephone
919-668-1121

Fax Telephone
919-668-1180

Training

• MD, Government Medical College (India), 1988

Residency

• Pediatrics, University of Bombay (India), 1988-1991
• Pediatrics, Stony Brook University Medical Center (New York), 1992-1995

Fellowship

• Pediatric Hematology-Oncology, Baylor College of Medicine (Texas), 1995-1998
• Pediatric Stem Cell Transplantation, Baylor College of Medicine (Texas), 2002-2003

Clinical Interests
Stem-cell (cord blood, peripheral blood, bone marrow) transplantation for hemoglobinopathies such as sickle-cell disease and thalassemia; inherited metabolic disorders, immune disorders, and childhood malignancies; reduced-intensity transplantation for non-malignant diseases

Research Interests
Stem cell transplantation for a variety of disorders - ranging from malignant diseases such as leukemia, lymphoma and myelodysplastic syndrome to nonmalignant diseases such as sickle cell disease, thalassemias, aplastic anemia, histiocytosis and leukodystrophies. My clinical research interest is stem cell transplantation for children with hemoglobinopathies such as sickle cell anemia,thalassemia and other non-malignant disorders. In addition,I am interested in developing startegies, such as reduced intensity conditioning, to make transplant safer.

Industry Relationships and Collaborations (What's this?)

This faculty member has no reported relationships with industry.

Representative Publications
Kanda, J; Kaynar, L; Kanda, Y; Prasad, VK; Parikh, SH; Lan, L; Shen, T; Rizzieri, DA; Long, GD; Sullivan, KM; Gasparetto, C; Chute, JP; Morris, A; Winkel, S; McPherson, J; Kurtzberg, J; Chao, NJ; Horwitz, ME. Pre-engraftment syndrome after myeloablative dual umbilical cord blood transplantation: risk factors and response to treatment. Bone Marrow Transplantation. 2013; (2013) Abstract

Heimall, J; Keller, M; Saltzman, R; Bunin, N; McDonald-McGinn, D; Zakai, E; de Villartay, JP; Moshous, D; Ariue, B; McCarthy, EA; Devlin, BH; Parikh, S; Buckley, RH; Markert, ML. Diagnosis of 22q11.2 deletion syndrome and artemis deficiency in two children with T-B-NK+ immunodeficiency. Journal of Clinical Immunology. 2012;32:1141-1144. (2012) Abstract

Kamani, NR; Walters, MC; Carter, S; Aquino, V; Brochstein, JA; Chaudhury, S; Eapen, M; Freed, BM; Grimley, M; Levine, JE; Logan, B; Moore, T; Panepinto, J; Parikh, S; Pulsipher, MA; Sande, J; Schultz, KR; Spellman, S; Shenoy, S. Unrelated donor cord blood transplantation for children with severe sickle cell disease: results of one cohort from the phase II study from the Blood and Marrow Transplant Clinical Trials Network (BMT CTN). Biology of Blood and Marrow Transplantation. 2012;18:1265-1272. (2012) Abstract

Parikh, S; Szabolcs, P. Reduced-intensity conditioning (RIC) in children with nonmalignant disorders (NMD) undergoing unrelated donor umbilical cord blood transplantation (UCBT). Biology of Blood and Marrow Transplantation. 2012;18:S53-S55. (2012) Abstract

Tewari, P; Martin, PL; Mendizabal, A; Parikh, SH; Page, KM; Driscoll, TA; Malech, HL; Kurtzberg, J; Prasad, VK. Myeloablative transplantation using either cord blood or bone marrow leads to immune recovery, high long-term donor chimerism and excellent survival in chronic granulomatous disease. Biology of Blood and Marrow Transplantation. 2012;18:1368-1377. (2012) Abstract

Peters, C; Cornish, JM; Parikh, SH; Kurtzberg, J. Stem cell source and outcome after hematopoietic stem cell transplantation (HSCT) in children and adolescents with acute leukemia. Pediatric Clinics of North America. 2010;57:27-46. (2010) Abstract

Boelens, JJ; Rocha, V; Aldenhoven, M; Wynn, R; O'Meara, A; Michel, G; Ionescu, I; Parikh, S; Prasad, VK; Szabolcs, P; Escolar, M; Gluckman, E; Cavazzana-Calvo, M; Kurtzberg, J; EUROCORD, Inborn error Working Party of EBMT and Duke University. Risk factor analysis of outcomes after unrelated cord blood transplantation in patients with hurler syndrome. Biology of Blood and Marrow Transplantation. 2009;15:618-625. (2009) Abstract

Parikh, SH; Mendizabal, A; Martin, PL; Prasad, VK; Szabolcs, P; Driscoll, TA; Kurtzberg, J. Unrelated donor umbilical cord blood transplantation in pediatric myelodysplastic syndrome: a single-center experience. Biology of Blood and Marrow Transplantation. 2009;15:948-955. (2009) Abstract

Page, KM; Mendizabal, AM; Prasad, VK; Martin, PL; Parikh, S; Wood, S; Sempowski, GD; Szabolcs, P; Kurtzberg, J. Posttransplant autoimmune hemolytic anemia and other autoimmune cytopenias are increased in very young infants undergoing unrelated donor umbilical cord blood transplantation. Biology of Blood and Marrow Transplantation. 2008;14:1108-1117. (2008) Abstract

Porkka, K; Koskenvesa, P; Lundán, T; Rimpiläinen, J; Mustjoki, S; Smykla, R; Wild, R; Luo, R; Arnan, M; Brethon, B; Eccersley, L; Hjorth-Hansen, H; Höglund, M; Klamova, H; Knutsen, H; Parikh, S; Raffoux, E; Gruber, F; Brito-Babapulle, F; Dombret, H; Duarte, RF; Elonen, E; Paquette, R; Zwaan, CM; Lee, FY. Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia. Blood. 2008;112:1005-1012. (2008) Abstract

Prasad, VK; Mendizabal, A; Parikh, SH; Szabolcs, P; Driscoll, TA; Page, K; Lakshminarayanan, S; Allison, J; Wood, S; Semmel, D; Escolar, ML; Martin, PL; Carter, S; Kurtzberg, J. Unrelated donor umbilical cord blood transplantation for inherited metabolic disorders in 159 pediatric patients from a single center: influence of cellular composition of the graft on transplantation outcomes. Blood. 2008;112:2979-2989. (2008) Abstract

Beam, D; Poe, MD; Provenzale, JM; Szabolcs, P; Martin, PL; Prasad, V; Parikh, S; Driscoll, T; Mukundan, S; Kurtzberg, J; Escolar, ML. Outcomes of unrelated umbilical cord blood transplantation for X-linked adrenoleukodystrophy. Biology of Blood and Marrow Transplantation. 2007;13:665-674. (2007) Abstract

Parikh, SH; Szabolcs, P; Prasad, VK; Lakshminarayanan, S; Martin, PL; Driscoll, TA; Kurtzberg, J. Correction of chronic granulomatous disease after second unrelated-donor umbilical cord blood transplantation. Pediatric Blood and Cancer. 2007;49:982-984. (2007) Abstract

Li, XN; Parikh, S; Shu, Q; Jung, HL; Chow, CW; Perlaky, L; Leung, HC; Su, J; Blaney, S; Lau, CC. Phenylbutyrate and phenylacetate induce differentiation and inhibit proliferation of human medulloblastoma cells. Clinical Cancer Research. 2004;10:1150-1159. (2004) Abstract

Parikh, SH; Chintagumpala, M; Hicks, MJ; Trautwein, LM; Blaney, S; Minifee, P; Woo, SY. Clear cell sarcoma of the kidney: an unusual presentation and review of the literature. Journal of Pediatric Hematology/Oncology. 1998;20:165-168. (1998) Abstract

Parikh, S; Bharucha, B; Kamdar, S; Kshirsagar, N. Polymorphonuclear leukocyte functions in children with cyanotic and acyanotic congenital heart disease. Indian Pediatrics. 1993;30:883-890. (1993) Abstract