Stuart J. McKinnon, MD, PhD
- Ophthalmology / Glaucoma Ophthalmology
- Neurobiology
Address
DUMC 3802
Durham, NC 27710
Appointment Telephone
919-681-3937
Fax Telephone
919-681-8267
- MD, Louisiana State University School of Medicine, 1990
- Ophthalmology, Louisiana State University Eye Center, 1995
- Glaucoma, Johns Hopkins School of Medicine (Maryland), 1996
- PhD, Physical Chemistry, University of New Orleans (Louisiana), 1990
Clinical Interests
Diagnosis and treatment of glaucoma and cataracts, laser and filtering procedures for glaucoma, complicated cataract surgery
Research Interests
Stuart J. McKinnon, MD, PhD, specializes in the diagnosis and treatment of glaucoma and cataract. His areas of expertise include open and closed angle glaucomas, neovascular and other secondary glaucomas, and juvenile glaucoma. He is experienced in all forms of anterior segment procedures including laser therapy and filtering surgeries for glaucoma, as well as cataract surgery. He is integrally involved in the teaching of medical students, residents, and fellows. McKinnon's research activities include NIH-sponsored exploration of the basic mechanisms of retinal cell death in glaucoma. Other research areas include neuroprotective glaucoma therapies, non-invasive imaging of glaucoma damage, and relationships between glaucoma and other chronic neurodegenerations such as Alzheimer's disease.
This faculty member (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.
- Retroject, Inc.
Representative Publications
Ivanov, D; Dvoriantchikova, G; Nathanson, L; McKinnon, SJ; Shestopalov, VI. Microarray analysis of gene expression in adult retinal ganglion cells. FEBS Letters. 2006;580:331-335.
(2006)
Abstract
Keltner, JL; Johnson, CA; Levine, RA; Fan, J; Cello, KE; Kass, MA; Gordon, MO. Normal visual field test results following glaucomatous visual field end points in the Ocular Hypertension Treatment Study. Archives of Ophthalmology. 2005;123:1201-1206.
(2005)
Abstract
Brandt, JD; Beiser, JA; Gordon, MO; Kass, MA; Ocular Hypertension Treatment Study (OHTS) Group. Central corneal thickness and measured IOP response to topical ocular hypotensive medication in the Ocular Hypertension Treatment Study. American Journal of Ophthalmology. 2004;138:717-722.
(2004)
Abstract
Coleman, AL; Gordon, MO; Beiser, JA; Kass, MA; Ocular Hypertension Treatment Study. Baseline risk factors for the development of primary open-angle glaucoma in the Ocular Hypertension Treatment Study. American Journal of Ophthalmology. 2004;138:684-685.
(2004)
Abstract
Higginbotham, EJ; Gordon, MO; Beiser, JA; Drake, MV; Bennett, GR; Wilson, MR; Kass, MA; Ocular Hypertension Treatment Study Group. The Ocular Hypertension Treatment Study: topical medication delays or prevents primary open-angle glaucoma in African American individuals. Archives of Ophthalmology. 2004;122:813-820.
(2004)
Abstract
Reitsamer, HA; Kiel, JW; Harrison, JM; Ransom, NL; McKinnon, SJ. Tonopen measurement of intraocular pressure in mice. Experimental Eye Research. 2004;78:799-804.
(2004)
Abstract
Tahzib, NG; Ransom, NL; Reitsamer, HA; McKinnon, SJ. Alpha-fodrin is cleaved by caspase-3 in a chronic ocular hypertensive (COH) rat model of glaucoma. Brain Research Bulletin. 2004;62:491-495.
(2004)
Abstract
Keltner, JL; Johnson, CA; Cello, KE; Edwards, MA; Bandermann, SE; Kass, MA; Gordon, MO; Ocular Hypertension Treatment Study Group. Classification of visual field abnormalities in the ocular hypertension treatment study. Archives of Ophthalmology. 2003;121:643-650.
(2003)
Abstract
Mayo, GL; Melendez, RF; Kumar, N; McKinnon, SJ; Glickman, RD. Antibody-targeted photodynamic therapy. American Journal of Ophthalmology. 2003;136:1151-1152.
(2003)
Abstract
McKinnon, SJ. Glaucoma: ocular Alzheimer's disease?. Frontiers in Bioscience. 2003;8:s1140-s1156.
(2003)
Abstract
Feuer, WJ; Parrish, RK; Schiffman, JC; Anderson, DR; Budenz, DL; Wells, MC; Hess, DJ; Kass, MA; Gordon, MO. The Ocular Hypertension Treatment Study: reproducibility of cup/disk ratio measurements over time at an optic disc reading center. American Journal of Ophthalmology. 2002;133:19-28.
(2002)
Abstract
Gordon, MO; Beiser, JA; Brandt, JD; Heuer, DK; Higginbotham, EJ; Johnson, CA; Keltner, JL; Miller, JP; Parrish, RK; Wilson, MR; Kass, MA. The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma. Archives of Ophthalmology. 2002;120:714-720.
(2002)
Abstract
Johnson, CA; Keltner, JL; Cello, KE; Edwards, M; Kass, MA; Gordon, MO; Budenz, DL; Gaasterland, DE; Werner, E; Ocular Hypertension Study Group. Baseline visual field characteristics in the ocular hypertension treatment study. Ophthalmology. 2002;109:432-437.
(2002)
Abstract
Kass, MA; Heuer, DK; Higginbotham, EJ; Johnson, CA; Keltner, JL; Miller, JP; Parrish, RK; Wilson, MR; Gordon, MO. The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. Archives of Ophthalmology. 2002;120:701-713.
(2002)
Abstract
Mayo, GL; Carter, JE; McKinnon, SJ. Bilateral optic disk edema and blindness as initial presentation of acute lymphocytic leukemia. American Journal of Ophthalmology. 2002;134:141-142.
(2002)
Abstract
McKinnon, SJ; Lehman, DM; Kerrigan-Baumrind, LA; Merges, CA; Pease, ME; Kerrigan, DF; Ransom, NL; Tahzib, NG; Reitsamer, HA; Levkovitch-Verbin, H; Quigley, HA; Zack, DJ. Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension. Investigative Ophthalmology and Visual Science. 2002;43:1077-1087.
(2002)
Abstract
McKinnon, SJ; Lehman, DM; Tahzib, NG; Ransom, NL; Reitsamer, HA; Liston, P; LaCasse, E; Li, Q; Korneluk, RG; Hauswirth, WW. Baculoviral IAP repeat-containing-4 protects optic nerve axons in a rat glaucoma model. Molecular Therapy. 2002;5:780-787.
(2002)
Abstract
Sponsel, WE; Paris, G; Trigo, Y; Pena, M; Weber, A; Sanford, K; McKinnon, S. Latanoprost and brimonidine: therapeutic and physiologic assessment before and after oral nonsteroidal anti-inflammatory therapy. American Journal of Ophthalmology. 2002;133:11-18.
(2002)
Abstract
Brandt, JD; Beiser, JA; Kass, MA; Gordon, MO. Central corneal thickness in the Ocular Hypertension Treatment Study (OHTS). Ophthalmology. 2001;108:1779-1788.
(2001)
Abstract
Keltner, JL; Johnson, CA; Quigg, JM; Cello, KE; Kass, MA; Gordon, MO. Confirmation of visual field abnormalities in the Ocular Hypertension Treatment Study. Ocular Hypertension Treatment Study Group. Archives of Ophthalmology. 2000;118:1187-1194.
(2000)
Abstract
Pease, ME; McKinnon, SJ; Quigley, HA; Kerrigan-Baumrind, LA; Zack, DJ. Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma. Investigative Ophthalmology and Visual Science. 2000;41:764-774.
(2000)
Abstract
Quigley, HA; McKinnon, SJ; Zack, DJ; Pease, ME; Kerrigan-Baumrind, LA; Kerrigan, DF; Mitchell, RS. Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats. Investigative Ophthalmology and Visual Science. 2000;41:3460-3466.
(2000)
Abstract
Gordon, MO; Kass, MA. The Ocular Hypertension Treatment Study: design and baseline description of the participants. Archives of Ophthalmology. 1999;117:573-583.
(1999)
Abstract
Jacob, JT; Burgoyne, CF; McKinnon, SJ; Tanji, TM; LaFleur, PK; Duzman, E. Biocompatibility response to modified Baerveldt glaucoma drains. Journal of Biomedical Materials Research Part B: Applied Biomaterials. 1998;43:99-107.
(1998)
Abstract
McKinnon, SJ. Glaucoma, apoptosis, and neuroprotection. Current Opinion in Ophthalmology. 1997;8:28-37.
(1997)
Abstract
