Department / Division:
Anesthesiology

Address:
DUMC 3094
Durham, NC 27710

Office Telephone:
919-681-6614

Fax Telephone:
919-681-8994

• MD, Vanderbilt University School of Medicine (Tennessee), 1986

• Internal Medicine, Tripler Army Medical Center (Hawaii), 1989
• Anesthesiology, Duke University Medical Center, 1997

• Critical Care Medicine, University of Utah Affiliated Hospitals, 1991

Clinical Interests:
Cardiac and thoracic anesthesia; transfusion medicine; transesophageal echocardiography; perioperative intensive care

Research Interests:
Current research interests include outcome analysis of cardiothoracic surgical patients as well as transfusion safety and clinical trials of blood management strategies.  Serving as Co-Director of the Acute Cardiothoracic Surgical Unit provides an opportunity to continue cardiac surgical outcomes research as part of the Cardiothoracic Anesthesiology Research Endeavors (CARE) Group.  As Co-Director of the Duke Center for Blood Conservation, I have the opportunity to study the impact of blood management on patient outcomes and plan to be further involved in research protocols involving oxygen therapeutic agents. Current protocols include a phase 4 trial of blood conservation techniques in multi-level spine surgery and a phase 2 trial of colloid therapy in cardiac surgery.  An ongoing  randomized, controlled trial of the impact of optimal fluid management on perioperative transfusion requirements for major urologic surgery should complete within one year.  Completed projects include a database investigation of the effect of intraoperative physiologic variables on mortality and neurologic outcome in coronary artery bypass surgery patients and phase 2 trials of oxygen therapeutic agents in cardiac surgery.  Thanks to the support of a grant from the Foundation for Anesthesia Education and Research (FAER), a randomized, double-blinded, placebo-controlled, efficacy trial of paravertebral nerve blockade for thoracoscopic pulmonary resection has been completed with results published in the May 2006 issue of Anesthesiology.  

Representative Publications:
Mathew JP, Mackensen GB, Phillips-Bute B, Stafford-Smith M, Podgoreanu MV, Grocott HP, Hill SE, Smith PK, Blumenthal JA, Reves JG, Newman MF, . Effects of extreme hemodilution during cardiac surgery on cognitive function in the elderly. Anesthesiology. 2007 Oct;107(4):577-84. (2007) Abstract

Hill SE, D'Alonzo RC.  Perioperative management of bleeding and transfusion.  In: Newman MF, Fleischer L, Longnecker DE, editors.  Perioperative Medicine: Managing for Outcome.  Philadelphia: Elsevier; 2007. Chapter 27. (2007)

, Ferraris VA, Ferraris SP, Saha SP, Hessel EA 2nd, Haan CK, Royston BD, Bridges CR, Higgins RS, Despotis G, Brown JR, , Spiess BD, Shore-Lesserson L, Stafford-Smith M, Mazer CD, Bennett-Guerrero E, Hill SE, Body S. Perioperative blood transfusion and blood conservation in cardiac surgery: the Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists clinical practice guideline. Ann Thorac Surg. 2007 May;83(5 Suppl):S27-86. (2007) Abstract

Hill SE, Keller RA, Stafford-Smith M, Grichnik K, White WD, D'Amico TA, Newman MF. Efficacy of single-dose, multilevel paravertebral nerve blockade for analgesia after thoracoscopic procedures. Anesthesiology. 2006 May;104(5):1047-53. (2006) Abstract

Lanzinger MJ, Niklason LE, Shannon M, Hill SE. Use of hemoglobin raffimer for postoperative life-threatening anemia in a Jehovah's Witness. Can J Anaesth. 2005 Apr;52(4):369-73. (2005) Abstract

Hill SE, Grocott HP, Leone BJ, White WD, Newman MF, . Cerebral physiology of cardiac surgical patients treated with the perfluorocarbon emulsion, AF0144. Ann Thorac Surg. 2005 Oct;80(4):1401-7. (2005) Abstract

Grichnik KP, Hill SE. The perioperative management of patients with severe emphysema. J Cardiothorac Vasc Anesth. 2003 Jun;17(3):364-87. (2003) Abstract

Hill SE, Leone BJ, Faithfull NS, Flaim KE, Keipert PE, Newman MF. Perflubron emulsion (AF0144) augments harvesting of autologous blood: A phase II study in cardiac surgery. J Cardiothorac Vasc Anesth. 2002 Oct;16(5):555-60. (2002) Abstract

Hill SE, Gottschalk LI, Grichnik K. Safety and preliminary efficacy of hemoglobin raffimer for patients undergoing coronary artery bypass surgery. J Cardiothorac Vasc Anesth. 2002 Dec;16(6):695-702. (2002) Abstract

Hill SE. Oxygen therapeutics--current concepts. Can J Anaesth. 2001 Apr;48(4 Suppl):S32-40. (2001) Abstract

van Wermeskerken GK, Lardenoye JW, Hill SE, Grocott HP, Phillips-Bute B, Smith PK, Reves JG, Newman MF. Intraoperative physiologic variables and outcome in cardiac surgery: Part II. Neurologic outcome. Ann Thorac Surg. 2000 Apr;69(4):1077-83. (2000) Abstract

Hill SE, van Wermeskerken GK, Lardenoye JW, Phillips-Bute B, Smith PK, Reves JG, Newman MF. Intraoperative physiologic variables and outcome in cardiac surgery: Part I. In-hospital mortality. Ann Thorac Surg. 2000 Apr;69(4):1070-5; discussion 1075-6. (2000) Abstract

Hill SE, Heldman LS, Goo ED, Whippo PE, Perkinson JC. Fatal microvascular pulmonary emboli from precipitation of a total nutrient admixture solution. JPEN J Parenter Enteral Nutr. 1996 Jan-Feb;20(1):81-7. (1996) Abstract