Stephen R. Smith, MD, MHS
Department / Division
Medicine /
Medicine-Nephrology
Address
2424 Erwin Road, Suite 605
Durham, NC 27705
Appointment Telephone
919-668-7630
Office Telephone
919-660-6865
Fax Telephone
919-684-4476
- MD, Duke University School of Medicine, 1985
- Internal Medicine, Duke University Medical Center, 1985-1988
- Nephrology, Duke University Medical Center, 1988-1991
- MHS, Duke University, 1994
Clinical Interests
Kidney transplantation, hypertension, consultative nephrology
Research Interests
Ongoing work focuses on problems of immediate clinical relevance in renal and pancreas transplantation, including issues related to immunosuppression, infection, and cardiovascular events as well as hypertension.
Research methodologies employed include randomized clinical trials, cohort studies, and retrospective multivariable analyses based on the transplant database.
Current studies include multiple industry sponsored immunosuppressive agent trials. We are also studying operating characteristics of diagnostic tests for BK polyoma nephritis and the utility of resection of failed renal allografts with regard to mortality, time to retransplantation, and success of subsequent transplants.
This physician has no reported relationships with industry.
Representative Publications
Bostom AG, Carpenter MA, Kusek JW, Levey AS, Hunsicker L, Pfeffer MA, Selhub J, Jacques PF, Cole E, Gravens-Mueller L, House AA, Kew C, McKenney JL, Pacheco-Silva A, Pesavento T, Pirsch J, Smith S, Solomon S, Weir M. Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: primary results from the Folic Acid for Vascular Outcome Reduction in Transplantation trial. Circulation. 2011 Apr 26;123(16):1763-70.
(2011)
Abstract
Goetzinger AM, Blumenthal JA, O'Hayer CV, Babyak MA, Hoffman BM, Ong L, Davis RD, Smith SR, Rogers JG, Milano CA, Smith AD, Kuo PC, Palmer SM. Stress and coping in caregivers of patients awaiting solid organ transplantation. Clin Transplant. 2011 Mar 13.
(2011)
Abstract
Lehrich RW, Pun PH, Tanenbaum ND, Smith SR, Middleton JP. Automated external defibrillators and survival from cardiac arrest in the outpatient hemodialysis clinic. J Am Soc Nephrol. 2007 Jan;18(1):312-20.
(2007)
Abstract
Palmer SM, Burch LH, Mir S, Smith SR, Kuo PC, Herczyk WF, Reinsmoen NL, Schwartz DA. Donor polymorphisms in Toll-like receptor-4 influence the development of rejection after renal transplantation. Clin Transplant. 2006 Jan-Feb;20(1):30-6.
(2006)
Abstract
Lehrich RW, Rocha PN, Reinsmoen N, Greenberg A, Butterly DW, Howell DN, Smith SR. Intravenous immunoglobulin and plasmapheresis in acute humoral rejection: experience in renal allograft transplantation. Hum Immunol. 2005 Apr;66(4):350-8.
(2005)
Abstract
Rocha PN, Plumb TJ, Miller SE, Howell DN, Smith SR. Risk factors for BK polyomavirus nephritis in renal allograft recipients. Clin Transplant. 2004 Aug;18(4):456-62.
(2004)
Abstract
Kurella M, Butterly DW, Smith SR. Post transplant erythrocytosis in hypercalcemic renal transplant recipients. Am J Transplant. 2003 Jul;3(7):873-7.
(2003)
Abstract
Smith SR, Butterly DW. Declining influence of race on the outcome of living-donor renal transplantation. Am J Transplant. 2002 Mar;2(3):282-6.
(2002)
Abstract
Howell DN, Smith SR, Butterly DW, Klassen PS, Krigman HR, Burchette JL Jr, Miller SE. Diagnosis and management of BK polyomavirus interstitial nephritis in renal transplant recipients. Transplantation. 1999 Nov 15;68(9):1279-88.
(1999)
Abstract
Smith SR, Minda SA, Samsa GP, Harrell FE Jr, Gunnells JC, Coffman TM, Butterly DW. Late withdrawal of cyclosporine in stable renal transplant recipients. Am J Kidney Dis. 1995 Sep;26(3):487-94.
(1995)
Abstract
Smith SR, Coffman TM, Svetkey LP. Effect of low-dose aspirin on thromboxane production and the antihypertensive effect of captopril. J Am Soc Nephrol. 1993 Nov;4(5):1133-9.
(1993)
Abstract
Smith SR, Svetkey LP, Dennis VW. Racial differences in the incidence and progression of renal diseases. Kidney Int. 1991 Nov;40(5):815-22.
(1991)
Abstract
