Stephen R. Smith, MD, MHS
Department / Division
Medicine /
Medicine-Nephrology
Address
2424 Erwin Road, Suite 605
Durham, NC 27705
Appointment Telephone
919-668-7630
Office Telephone
919-660-6865
Fax Telephone
919-684-4476
- MD, Duke University School of Medicine, 1985
- Internal Medicine, Duke University Medical Center, 1985-1988
- Nephrology, Duke University Medical Center, 1988-1991
- MHS, Duke University, 1994
Clinical Interests
Kidney transplantation, hypertension, consultative nephrology
Research Interests
Ongoing work focuses on problems of immediate clinical relevance in renal and pancreas transplantation, including issues related to immunosuppression, infection, and cardiovascular events as well as hypertension.
Research methodologies employed include randomized clinical trials, cohort studies, and retrospective multivariable analyses based on the transplant database.
Current studies include multiple industry sponsored immunosuppressive agent trials. We are also studying operating characteristics of diagnostic tests for BK polyoma nephritis and the utility of resection of failed renal allografts with regard to mortality, time to retransplantation, and success of subsequent transplants.
This faculty member has no reported relationships with industry.
Representative Publications
Goetzinger, AM; Blumenthal, JA; O'Hayer, CV; Babyak, MA; Hoffman, BM; Ong, L; Davis, RD; Smith, SR; Rogers, JG; Milano, CA; Smith, AD; Kuo, PC; Palmer, SM. Stress and coping in caregivers of patients awaiting solid organ transplantation. Clinical Transplantation. 2012;26:97-104.
(2012)
Abstract
Bostom, AG; Carpenter, MA; Kusek, JW; Levey, AS; Hunsicker, L; Pfeffer, MA; Selhub, J; Jacques, PF; Cole, E; Gravens-Mueller, L; House, AA; Kew, C; McKenney, JL; Pacheco-Silva, A; Pesavento, T; Pirsch, J; Smith, S; Solomon, S; Weir, M. Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: primary results from the Folic Acid for Vascular Outcome Reduction in Transplantation trial. Circulation. 2011;123:1763-1770.
(2011)
Abstract
Lehrich, RW; Pun, PH; Tanenbaum, ND; Smith, SR; Middleton, JP. Automated external defibrillators and survival from cardiac arrest in the outpatient hemodialysis clinic. Journal of the American Society of Nephrology. 2007;18:312-320.
(2007)
Abstract
Palmer, SM; Burch, LH; Mir, S; Smith, SR; Kuo, PC; Herczyk, WF; Reinsmoen, NL; Schwartz, DA. Donor polymorphisms in Toll-like receptor-4 influence the development of rejection after renal transplantation. Clinical Transplantation. 2006;20:30-36.
(2006)
Abstract
Lehrich, RW; Rocha, PN; Reinsmoen, N; Greenberg, A; Butterly, DW; Howell, DN; Smith, SR. Intravenous immunoglobulin and plasmapheresis in acute humoral rejection: experience in renal allograft transplantation. Human Immunology. 2005;66:350-358.
(2005)
Abstract
Rocha, PN; Plumb, TJ; Miller, SE; Howell, DN; Smith, SR. Risk factors for BK polyomavirus nephritis in renal allograft recipients. Clinical Transplantation. 2004;18:456-462.
(2004)
Abstract
Kurella, M; Butterly, DW; Smith, SR. Post transplant erythrocytosis in hypercalcemic renal transplant recipients. American Journal of Transplantation. 2003;3:873-877.
(2003)
Abstract
Smith, SR; Butterly, DW. Declining influence of race on the outcome of living-donor renal transplantation. American Journal of Transplantation. 2002;2:282-286.
(2002)
Abstract
Howell, DN; Smith, SR; Butterly, DW; Klassen, PS; Krigman, HR; Burchette, JL; Miller, SE. Diagnosis and management of BK polyomavirus interstitial nephritis in renal transplant recipients. Transplantation. 1999;68:1279-1288.
(1999)
Abstract
Smith, SR; Minda, SA; Samsa, GP; Harrell, FE; Gunnells, JC; Coffman, TM; Butterly, DW. Late withdrawal of cyclosporine in stable renal transplant recipients. American Journal of Kidney Diseases. 1995;26:487-494.
(1995)
Abstract
Smith, SR; Coffman, TM; Svetkey, LP. Effect of low-dose aspirin on thromboxane production and the antihypertensive effect of captopril. Journal of the American Society of Nephrology. 1993;4:1133-1139.
(1993)
Abstract
Smith, SR; Svetkey, LP; Dennis, VW. Racial differences in the incidence and progression of renal diseases. Kidney International. 1991;40:815-822.
(1991)
Abstract
