Department / Division
Medicine /
Medicine-Neurology
Address
DUMC 102350
Durham, NC 27710
Appointment Telephone
919-668-7600
Office Telephone
919-684-3532
Fax Telephone
919-684-8955
Clinical Interests
Epilepsy, epilepsy surgery with emphasis on difficult-to-control/treat patients
Research Interests
My research and clinical interests are in improving surgical outcomes for patients with intractable seizures and normal imaging studies (non-lesional epilepsy).
This faculty member (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.
Representative Publications
Kossoff, EH; Rowley, H; Sinha, SR; Vining, EP. A prospective study of the modified Atkins diet for intractable epilepsy in adults. Epilepsia. 2008;49:316-319.
(2008)
Abstract
Huang, YH; Muralidharan, S; Sinha, SR; Kao, JP; Bergles, DE. Ncm-D-aspartate: a novel caged D-aspartate suitable for activation of glutamate transporters and N-methyl-D-aspartate (NMDA) receptors in brain tissue. Neuropharmacology. 2005;49:831-842.
(2005)
Abstract
Sinha, SR; Crone, NE; Fotta, R; Lenz, F; Boatman, DF. Transient unilateral hearing loss induced by electrocortical stimulation. Neurology. 2005;64:383-385.
(2005)
Abstract
Sinha, SR; Kossoff, EH. The ketogenic diet. The Neurologist. 2005;11:161-170.
(2005)
Abstract
Huang, YH; Sinha, SR; Tanaka, K; Rothstein, JD; Bergles, DE. Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons. The Journal of Neuroscience. 2004;24:4551-4559.
(2004)
Abstract
Dooley, KE; Sinha, SR; Haponik, E; Conwit, R; Sevransky, JE. A 39-year-old man with hip pain and respiratory failure. Chest. 2002;121:1345-1349.
(2002)
Abstract
Sinha, SR; Saggau, P. Imaging of 4-AP-induced, GABA(A)-dependent spontaneous synchronized activity mediated by the hippocampal interneuron network. Journal of Neurophysiology. 2001;86:381-391.
(2001)
Abstract
Sinha, SR; Saggau, P. Simultaneous optical recording of membrane potential and intracellular calcium from brain slices. Methods. 1999;18:204-175.
(1999)
Abstract
Sinha, SR; Wu, LG; Saggau, P. Presynaptic calcium dynamics and transmitter release evoked by single action potentials at mammalian central synapses. Biophysical Journal. 1997;72:637-651.
(1997)
Abstract
Sinha, SR; Patel, SS; Saggau, P. Simultaneous optical recording of evoked and spontaneous transients of membrane potential and intracellular calcium concentration with high spatio-temporal resolution. Journal of Neuroscience Methods. 1995;60:49-60.
(1995)
Abstract
Nathan, SS; Sinha, SR; Gordon, B; Lesser, RP; Thakor, NV. Determination of current density distributions generated by electrical stimulation of the human cerebral cortex. Electroencephalography and Clinical Neurophysiology. 1993;86:183-192.
(1993)
Abstract
