Saurabh R. Sinha, MD, PhD
Department / Division
Medicine /
Medicine-Neurology
Address
DUMC 102350
Durham, NC 27710
Appointment Telephone
919-668-7600
Office Telephone
919-684-3532
Fax Telephone
919-684-8955
- MD, Baylor College of Medicine (Texas), 1999
- Neurology, Johns Hopkins Hospital (Maryland), 2003
- Clinical Neurophysiology, Johns Hopkins Hospital (Maryland), 2004
- Epilepsy, Johns Hopkins Hospital (Maryland), 2005
- PhD, Neuroscience, Baylor College of Medicine (Texas), 1997
Clinical Interests
Epilepsy, epilepsy surgery with emphasis on difficult-to-control/treat patients
Research Interests
My research and clinical interests are in improving surgical outcomes for patients with intractable seizures and normal imaging studies (non-lesional epilepsy).
This faculty member (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.
- ABRET
- Cyberonics, Inc.
- Lundbeck
- UCB Pharma
- Wyeth (Pfizer)
Representative Publications
Kossoff EH, Rowley H, Sinha SR, Vining EP. A prospective study of the modified Atkins diet for intractable epilepsy in adults. Epilepsia. 2008 Feb;49(2):316-9.
(2008)
Abstract
Huang YH, Muralidharan S, Sinha SR, Kao JP, Bergles DE. Ncm-D-aspartate: a novel caged D-aspartate suitable for activation of glutamate transporters and N-methyl-D-aspartate (NMDA) receptors in brain tissue. Neuropharmacology. 2005 Nov;49(6):831-42.
(2005)
Abstract
Sinha SR, Crone NE, Fotta R, Lenz F, Boatman DF. Transient unilateral hearing loss induced by electrocortical stimulation. Neurology. 2005 Jan 25;64(2):383-5.
(2005)
Abstract
Sinha SR, Kossoff EH. The ketogenic diet. Neurologist. 2005 May;11(3):161-70.
(2005)
Abstract
Huang YH, Sinha SR, Tanaka K, Rothstein JD, Bergles DE. Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons. J Neurosci. 2004 May 12;24(19):4551-9.
(2004)
Abstract
Dooley KE, Sinha SR, Haponik E, Conwit R, Sevransky JE. A 39-year-old man with hip pain and respiratory failure. Chest. 2002 Apr;121(4):1345-9.
(2002)
Abstract
Sinha SR, Saggau P. Imaging of 4-AP-induced, GABA(A)-dependent spontaneous synchronized activity mediated by the hippocampal interneuron network. J Neurophysiol. 2001 Jul;86(1):381-91.
(2001)
Abstract
Sinha SR, Saggau P. Simultaneous optical recording of membrane potential and intracellular calcium from brain slices. Methods. 1999 Jun;18(2):204-14, 175.
(1999)
Abstract
Sinha SR, Wu LG, Saggau P. Presynaptic calcium dynamics and transmitter release evoked by single action potentials at mammalian central synapses. Biophys J. 1997 Feb;72(2 Pt 1):637-51.
(1997)
Abstract
Sinha SR, Patel SS, Saggau P. Simultaneous optical recording of evoked and spontaneous transients of membrane potential and intracellular calcium concentration with high spatio-temporal resolution. J Neurosci Methods. 1995 Aug;60(1-2):49-60.
(1995)
Abstract
Nathan SS, Sinha SR, Gordon B, Lesser RP, Thakor NV. Determination of current density distributions generated by electrical stimulation of the human cerebral cortex. Electroencephalogr Clin Neurophysiol. 1993 Mar;86(3):183-92.
(1993)
Abstract
