Physicians

Department / Division
Ophthalmology / Glaucoma Ophthalmology

Address
2000 Regency Parkway, Suite 100
Cary, NC 27518

Appointment Telephone
919-681-3937

Fax Telephone
919-681-8267

Training

• MD, Seth G.S. Medical College (India), 1988

Residency

• Ophthalmology, Duke Eye Center, 1997-2000

Fellowship

• Glaucoma, Duke Eye Center, 2001
• Research, Wilmer Institute, Johns Hopkins Hospital (Maryland)

Clinical Interests
Glaucoma (including laser and conventional surgery), cataract surgery, glaucoma implant surgery, research interests include new imaging techniques for glaucoma diagnosis and new surgical approaches to treating glaucoma

Research Interests
Research Focus:
· Development of new imaging technology for the early diagnosis of glaucoma using SD OCT to image retinal ganglion cells and trabecular meshwork and Schlemm's canal.  

· Detection and importance of fluctuations of intraocular pressure and ways to decrease such fluctuation.  

· Development of intraocular pressure sensor for telemetric eye pressure measurement

· Research into the causes and prevention of glaucoma in children particularly in pediatric aphakia and pseudophakia.


Research Projects:
1. Development and testing of a new glaucoma drainage device  
2. Schlemm's canal and trabecular meshwork imaging in narrow angle glaucoma
3. IOP fluctuations in different types of glaucoma and the effects of laser
4. Retinal thickness measurements in glaucoma suspect children
5. Retinal thickness mapping for diagnosis of glaucoma, ocular hypertension and  glaucoma suspects.

Industry Relationships and Collaborations (What's this?)

This physician (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.

• Alcon Laboratories
• Heidelberg Engineering
• Lumenis, Inc
• Merck Sharpe & Dohme (Merck & Co, USA)
• Pfizer Inc.

Representative Publications
El-Dairi MA, Asrani SG, Enyedi LB, Freedman SF. Optical coherence tomography in the eyes of normal children. Arch Ophthalmol. 2009 Jan;127(1):50-8. (2009) Abstract

Asrani S, Sarunic M, Santiago C, Izatt J.  Detailed Visualization of the Anterior Segment using Fourier Domain Optical Coherence Tomography, Arch Ophthalmol 126 (6); 765-71, 2008 (2008)

ElMallah MK, Asrani SG. New ways to measure intraocular pressure. Curr Opin Ophthalmol. 2008 Mar;19(2):122-6. (2008) Abstract

Sarunic M, Asrani S, Izatt J.  Imaging the Ocular Anterior Segment with Real time Full Range Fourier Domain Optical Coherence Tomography, Arch Ophthalmol.126(4):537-542; 2008 (2008)

Sit A, Asrani S.  Effects of medications and surgery on circadian intraocular pressure variations.  Surv Ophthalmol. 53 (6), p.S45-S55, 2008 (2008)

Katuri K, Asrani S, Ramsubramanian R.  Intraocular Pressure Monitoring Sensors, IEEE Sensors Journal, 8 (1): 13-19, 2008

Weizer J, Asrani S, Stinnett S, Herndon L.  The Clinical Utility of Dynamic Contour Tonometry and Ocular Pulse Amplitude, Journal of Glaucoma, 16 (8) 700-3; 2007
(2007)

Hess DB, Asrani SG, Bhide MG, Enyedi LB, Stinnett SS, Freedman SF. Macular and retinal nerve fiber layer analysis of normal and glaucomatous eyes in children using optical coherence tomography. Am J Ophthalmol. 2005 Mar;139(3):509-17. (2005) Abstract

Asrani S, Challa P, Herndon L, Lee P, Stinnett S, Allingham R.
Correlation between retinal thickness analysis, optic nerve and visual fields in glaucoma patients and suspects
Journal of Glaucoma, 12(2):119-28, 2003
(2003)

Asrani S, Herndon L, Allingham, R
Glaucoma Tube trimming; a newer technique
Arch Ophthalmol 2003;121:1324-26
(2003)

Asrani S, Zeimer R, Wilensky J, Geiser D, Vitale S, Lindenmuth K: Large Diurnal Fluctuations in Intraocular Pressure are an independent Risk Factor in Patients with Glaucoma Journal of Glaucoma -9:134-142, 2000 (2000)

Asrani S, Freedman S, Hasselbad V, Buckley E, Egbert J, Dahan E, Gimbel H, Johnson D, McClatchey S, Parks M, Plager D,  Maselli E Does primary Intraocular lens implantation prevent aphakic glaucoma? Journal of American Academy of Pediatric Ophthalmology and Strabismus-1999;3:33-39 (1999)

3. Zeimer R, Asrani S, Zou S, Quigley H, Jampel H Quantitative Detection of glaucomatous damage at the posterior pole by Retinal thickness mapping Ophthalmology 105(2):224-31, 1998 (1998)

Asrani S and Wilensky J: Management of bleb leaks after glaucoma filtering surgery. The Use of Autologous Fibrin Tissue Glue as an Alternative Ophthalmology  103:294-298;1996 (1996)

Asrani S, Zhou S, D'anna S, Phelan A, Goldberg M and Zeimer R: Selective visualization of choroidal neovascular membranes. Invest. Ophthal Vis Sci 1996;37:1642-1650 (1996)