Department / Division:
Pediatrics / Cardiology

Address:
DUMC 3090
Durham, NC 27710

Appointment Telephone:
919-668-4000

Office Telephone:
919-681-2916

Fax Telephone:
919-668-6122

• MD, Vanderbilt University School of Medicine (Tennessee), 1979

• Pediatrics, University of Florida, 1979-1983

• Pediatric Cardiology, University of Florida, 1983-1986
• Pediatric Cardiology, Children's Hospital Boston (Massachusetts), 1986

Clinical Interests:
Infants, children, teenagers, and young adults with syncope, cardiac arrhythmias, sudden death, autonomic dysfunction, or congenital heart disease; placement of cardiac pacemakers and implantable defibrillators; performance of tilt-table studies, autonomic studies, and electrophysiologic studies, and radiofrequency ablation of cardiac arrhythmias

Research Interests:
1.  We are interested in determining the long term effects of surgery for the Wolff-Parkinson-White Syndrome.  This is being carried out through medical record evaluation and telephone survey of 75 individuals who were operated on for Wolff-Parkinson-White Syndrome before the age of 17 years.  Specifically, we are interested in the incidence of recurrent or new arrhythmias, their educational experience, employability, history of childbearing, and current quality of life.

2.  We are developing a simple diagnostic device to help identify young patients whose symptom of palpitations is casued by supraventricular tachycardia.

3.  We are interested in evaluating the fate of the sinus node in children having congenital complete AV block.  We have noted a few children who besides having congenital AV block, also have abnormalities of sinus node function.  

4.  We continue our participation in a multi-institution registry of patients
5.  We are involved in an electrophysiology laboratory study investigating the efficacy of various ventilation modes to help stabilize catheters during EP testing.  This involves the use of a commercial Global Positioning System technology (Endocardial Solutions, Inc.)to verify catheter positions.

Representative Publications:
Arad M, Maron BJ, Gorham JM, Johnson WH, Saul JP, Perez-Atayde AR, Spirito P, Wright GB, Kanter RJ, Seidman CE, Seidman JG.  Glycogen storage diseases presenting as hypertrophic cardiomyopathy.  N Engl J Med  2005;352:362-372.

Kanter RJ.  Pace mapping the fast pathway in patients with atrioventricular nodal reentrant tachycardia:  Koch’s triangle or the Bermuda triangle?  J Cardiovasc Electrophysiol  2005;16:36-38.

Ansong AK, Li JS, Nozik-Grayck E, Ing R, Kravitz RM, Idriss SF, Kanter RJ, Rice H, Chen YT, Kishnani PS.  Electrocardiographic response to enzyme replacement therapy for Pompe disease. Genet Med 2006;8:297-301.

Papagiannis JP, Vachtsevanos L, Rammos S, Kanter R.  Cryoablation of a nodoventricular Mahaim fiber with the use of a three-dimensional mapping system.  J Interv Cardiol Elelectrophysiol 2005;14:111-116.

Bravender T, Kanter R, Zucker N.  Anorexia nervosa and second degree atrioventricular block (type I).  International J Eating Disorders 2006;39:612-615.

Horenstein MS, Idriss SF, Hamilton RM, Kanter RJ, Singh TP, Webster PA, Karpawich PP.  Efficacy of signal-averaged ECG in the young orthotopic heart transplant patient to detect allograft rejection: A multi-center study.  Pediatr Cardiol 2006;27:589-593. (2005)

Erb TO, Kanter RJ, Hall JM, Tong JG, Kern FH, Schulman SR.  A comparison of electrophysiologic effects of propofol and isoflurane based anesthetics in children undergoing radiofrequency catheter ablation for supraventricular tachycardia.  Anesthesiology 2002;96:1386-1394.

Van Hare GF, Chiesa NA, Campbell RM, Kanter RJ, Cecchin F.  Atrioventricular node reentrant tachycardia in children:  Effect of slow pathway ablation on fast pathway conduction.  J Cardiovasc Electrophysiol  2002;13:000-000.

Arad M, Benson DW, McKenna WJ, Perez-Atayde AR, Sparks EA, Kanter RJ, Winston F, Seidman JG, Seidman CE.  Constitutively active AMP kinase mutations cause ventricular preexcitation, atrioventricular block and glycogen storage disease mimicking hypertrophic cardiomyopathy.  J Clin Invest  2002;109:357-362.

Lee P-C, Kanter R, Gomez-Marin O, Wolff GS, Young M-L.  Quantitative assessment of atrofascicular/atrioventricular type Mahaim fibers.  J Cardiovasc Electrophysiol  2002;13:535-541.

Baker SS, Milazzo AS, Valente AM, Paul IM, Talner NS, Sanders SP, Kanter RJ, Li, JS.  Measures of cardiac repolarization and body position in infants.  Clin Pediatr  2003;42:67-70.
(2002)

24. Kanter RJ, Papagiannis J, Carboni MP, Ungerleider RM, Sanders WE, Wharton JM.  Radiofrequency catheter ablation of supraventricular tachycardia substrates following Mustard and Senning operations for d-transposition of the great arteries.  J Am Coll Cardiol  2000;35:428-441 (2000)

Kanter RJ. Syncopeand sudden death in children. In Garson A, Jr., Bricker JT, Fisher DJ, Neish SR (eds). The Science and Practice of Pediatric Cardiology, 2nd Edition. Baltimore, Williams & Wilkins, 1998; 2169-2199. (1998)

Kanter RJ, Garson A. Arrhythmias in congenital heart disease. In Topol EJ (ed). Textbook of Cardiovascular Medicine. Philadelphia,, Lippincott-Raven, 1998; 1997-2026. (1998)