Division Chief, Maternal-Fetal Medicine
Vice Chair, Administrative Affairs

Department / Division:
Obstetrics and Gynecology / Maternal-Fetal Medicine

Address:
DUMC 3967
Durham, NC 27710

Appointment Telephone:
919-668-7430 (Consultations)
919-684-2471 (Returning Patients)

Office Telephone:
919-681-5220

Fax Telephone:
919-681-7861 (Administration), 919-681-1397 (Clinical Records, Prescriptions)

• MD, Texas Tech University School of Medicine, 1986

• OB/GYN, UNC Hospitals, 1990

• Sexually Transmitted Diseases, University of North Carolina, 1991
• Maternal Fetal Medicine, University of Colorado, 1993

Clinical Interests:
High-risk obstetrics with an emphasis on medical complications of pregnancy, infectious diseases in pregnancy, preterm labor and delivery

Representative Publications:
Ellestad SC, Swamy GK, Sinclair T, James AH, Heine RP, Murtha AP. Preterm premature rupture of membrane management--inpatient versus outpatient: a retrospective review. Am J Perinatol. 2008 Jan;25(1):69-73. (2008) Abstract

Canzoneri BJ, Ellestad SC, Brancazio LR, Evans AK, Grotegut CA, Fitzpatrick B, Reddick K, Beiswenger TR, Small M, Boyd BK, Heine RP. P38.03: Prenatal diagnosis of an obstructing enterogenous cyst. Ultrasound Obstet Gynecol. 2008 Aug 11;32(3):442. (2008) Abstract

Simhan HN, Anderson BL, Krohn MA, Heine RP, Martinez de Tejada B, Landers DV, Hillier SL. Host immune consequences of asymptomatic Trichomonas vaginalis infection in pregnancy. Am J Obstet Gynecol. 2007 Jan;196(1):59.e1-5. (2007) Abstract

Pollak KI, Oncken CA, Lipkus IM, Lyna P, Swamy GK, Pletsch PK, Peterson BL, Heine RP, Brouwer RJ, Fish L, Myers ER. Nicotine replacement and behavioral therapy for smoking cessation in pregnancy. Am J Prev Med. 2007 Oct;33(4):297-305. (2007) Abstract

Murtha AP, Sinclair T, Hauser ER, Swamy GK, Herbert WN, Heine RP. Maternal serum cytokines in preterm premature rupture of membranes. Obstet Gynecol. 2007 Jan;109(1):121-7. (2007) Abstract

Murtha AP, Nieves A, Hauser ER, Swamy GK, Yonish BA, Sinclair TR, Heine RP. Association of maternal IL-1 receptor antagonist intron 2 gene polymorphism and preterm birth. Am J Obstet Gynecol. 2006 Nov;195(5):1249-53. (2006) Abstract

Mills AA, Yonish B, Feng L, Schomberg DW, Heine RP, Murtha AP. Characterization of progesterone receptor isoform expression in fetal membranes. Am J Obstet Gynecol. 2006 Oct;195(4):998-1003. (2006) Abstract

Swamy GK, Simhan HN, Gammill HS, Heine RP. Clinical utility of fetal fibronectin for predicting preterm birth. J Reprod Med. 2005 Nov;50(11):851-6. (2005) Abstract

Sutkin G, Krohn MA, Heine RP, Sweet RL. Antibiotic prophylaxis and non-group B streptococcal neonatal sepsis. Obstet Gynecol. 2005 Mar;105(3):581-6. (2005) Abstract

Simhan H, Krohn M, Heine RP. Obstetric rectal injury: risk factors and the role of physician experience. J Matern Fetal Neonatal Med. 2004 Nov;16(5):271-4. (2004) Abstract

Landers DV, Wiesenfeld HC, Heine RP, Krohn MA, Hillier SL. Predictive value of the clinical diagnosis of lower genital tract infection in women. Am J Obstet Gynecol. 2004 Apr;190(4):1004-10. (2004) Abstract

Klebanoff MA, Hauth JC, MacPherson CA, Carey JC, Heine RP, Wapner RJ, Iams JD, Moawad A, Miodovnik M, Sibai BM, vanDorsten JP, Dombrowski MP, . Time course of the regression of asymptomatic bacterial vaginosis in pregnancy with and without treatment. Am J Obstet Gynecol. 2004 Feb;190(2):363-70. (2004) Abstract

Heine RP, Ness RB, Roberts JM. Seroprevalence of antibodies to Chlamydia pneumoniae in women with preeclampsia. Obstet Gynecol. 2003 Feb;101(2):221-6. (2003) Abstract

Grable IA, Heine RP. Neutrophil granule products: can they identify subclinical chorioamnionitis in patients with preterm premature rupture of membranes? Am J Obstet Gynecol. 2003 Sep;189(3):808-12. (2003) Abstract

Brancazio LR, Murtha AP, Heine RP. Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone caproate. N Engl J Med. 2003 Sep 11;349(11):1087-8; author reply 1087-8. (2003) Abstract

Balu RB, Savitz DA, Ananth CV, Hartmann KE, Miller WC, Thorp JM, Heine RP. Bacterial vaginosis, vaginal fluid neutrophil defensins, and preterm birth. Obstet Gynecol. 2003 May;101(5 Pt 1):862-8. (2003) Abstract