Physicians

Department / Division
Ophthalmology / Glaucoma Ophthalmology

Address
DUMC 3802
Durham, NC 27710

Appointment Telephone
919-681-3937

Fax Telephone
919-681-8267

Training

• MD, University of Florida College of Medicine, 1993

Residency

• Internal Medicine, Emory University Hospital (Georgia), 1993-1995
• Ophthalmology, University of Florida College of Medicine, 1995-1998

Fellowship

• Glaucoma, Duke University Medical Center, 1998-2000

Clinical Interests
Diagnosis and treatment of glaucoma, including medical, laser, and surgical therapies; cataract evaluation and treatment; glaucoma implant surgery; combined glaucoma and cataract surgery; research interests include genetic studies of inherited eye diseases and novel drug-delivery techniques

Research Interests
As a physician-scientist investigator, Dr. Challa has a special research interest in the genetic basis of inherited eye diseases. He has active projects investigating the genetics of Pseudoexfoliation associated glaucoma and the cellular basis for glaucoma development. He also studies ocular drug delivery and is involved in developing long-term delivery devices for glaucoma medications. He also investigates novel compounds that may eventually be used for treating glaucoma. In addition to basic science research, he also has clinical research interests including evaluating the effectiveness of new glaucoma therapies.

Industry Relationships and Collaborations (What's this?)

This physician (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.

• Aerie Pharmaceuticals, Inc.

Representative Publications
Allingham, R.R., Seo B., Bembe M, Rampersaud E., Challa P., Parish, T., Gilbert J., Pericak-Vance M.A., Klintworth G.K., Vance J.M. A small duplication of the terminal region of chromosome 4p35 is associated with hereditary benign intrepithelial dyskeratosis, Am J Hum Genet. 2001 Feb; 68(2): 491-4. (2001)

Fanous M.M., Challa P., Maren T.H. Comparison of intraocular pressure lowering by topical and systemic carbonic anhydrase inhibitors in the rabbit. Ocul Pharmacol Ther. 1999 Feb; 15 (1): 51-7. (1999)

P. Challa, MD, L.W. Herndon, MD, M.A. Hauser, PhD, B.W. Broomer, CCRP, M.A. Pericak-Vance, PhD, R.R. Allingham, MD, Incidence of Myocilin Mutations in Individuals with POAG From West Africa. J. Glaucoma submitted

Pratap Challa, Kevin D. O'Neal, Leon W. Herndon, Terry A. Cox, Nauman R. Imami, MD and Paul P. Lee who Attends Community Eye Screenings? A Survey of Participants. Arch Ophthalmol Submitted

Rahul N. Khurana 1, MS, Paul P. Lee 123, MD, JD, Pratap Challa1, MD. Readability of Ocular Medication Inserts. Ophthalmology Submitted