Patrick J. Buckley, MD, PhD
Director, Division of Hematopathology
Director
Department / Division
Pathology /
Pathology Clinical Services
Address
DUMC 3712
Durham, NC 27710
Office Telephone
919-681-6578
Fax Telephone
919-684-1856
- MD, Washington University in Saint Louis School of Medicine (Missouri), 1976
- Residency/Fellowship, Pathology, Barnes Hospital/Washington University Medical Center (Missouri), 1976-1980
- PhD, Molecular Biology, University of Pennsylvania, 1972
Clinical Interests
Hematopathology and flow cytometry including bone-marrow and lymph-node interpretation for adult and pediatric hematopoietic diseases; more than 30 years of experience in adult and pediatric hematologic diseases.
Please send all consultation slides to Patrick J. Buckley, MD, PhD, c/o Carol Tate, Consultation Services, Department of Pathology, DUMC 3712, Room M345, Davison Building, Green Zone, Erwin Road, Durham, NC 27710
Research Interests
1. The use of morphology, flow cytometry, cytogenetics, molecular techniques, and analysis of cell products to study the diagnosis, classification, and biological features of lymphoid and myeloid neoplasms (lymphoma/leukemia) in adults and children.
2. Investigation of new strategies for educating residents for careers in anatomic pathology and laboratory medicine.
This faculty member has no reported relationships with industry.
Representative Publications
Matloub, Y; Bostrom, BC; Hunger, SP; Stork, LC; Angiolillo, A; Sather, H; La, M; Gastier-Foster, JM; Heerema, NA; Sailer, S; Buckley, PJ; Thomson, B; Cole, C; Nachman, JB; Reaman, G; Winick, N; Carroll, WL; Devidas, M; Gaynon, PS. Escalating intravenous methotrexate improves event-free survival in children with standard-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood. 2011;118:243-251.
(2011)
Abstract
Gong, JZ; Snyder, MJ; Lagoo, AS; Vollmer, RT; Dash, RR; Madden, JF; Buckley, PJ; Jones, CK. Diagnostic impact of core-needle biopsy on fine-needle aspiration of non-Hodgkin lymphoma. Diagnostic Cytopathology. 2004;31:23-30.
(2004)
Abstract
Tirado, CA; Golembiewski-Ruiz, V; Horvatinovich, J; Moore, JO; Buckley, PJ; Stenzel, TT; Goodman, BK. Cytogenetic and molecular analysis of an unusual case of acute promyelocytic leukemia with a t(15;17;17)(q22;q23;q21). Cancer Genetics and Cytogenetics. 2003;145:31-37.
(2003)
Abstract
Gong, JZ; Lagoo, AS; Peters, D; Horvatinovich, J; Benz, P; Buckley, PJ. Value of CD23 determination by flow cytometry in differentiating mantle cell lymphoma from chronic lymphocytic leukemia/small lymphocytic lymphoma. American Journal of Clinical Pathology. 2001;116:893-897.
(2001)
Abstract
Lagoo, AS; Buckley, PJ; Burchell, LJ; Peters, D; Fechner, JH; Tsuchida, M; Dong, Y; Hong, X; Brunner, KG; Oberley, TD; Hamawy, MM; Knechtle, SJ. Increased glomerular deposits of von Willebrand factor in chronic, but not acute, rejection of primate renal allografts. Transplantation. 2000;70:877-886.
(2000)
Abstract
Hughes, D; Buckley, PJ. Idiopathic retroperitoneal fibrosis is a macrophage-rich process. Implications for its pathogenesis and treatment. American Journal of Surgical Pathology. 1993;17:482-490.
(1993)
Abstract
Spinelli, HM; Criscuolo, GR; Tripps, M; Buckley, PJ. Massive orbital teratoma in the newborn. Annals of Plastic Surgery. 1993;31:453-458.
(1993)
Abstract
Tallini, G; West, AB; Buckley, PJ. Diagnosis of gastrointestinal T-cell lymphomas in routinely processed tissues. Journal of Clinical Gastroenterology. 1993;17:57-66.
(1993)
Abstract
Buckley, PJ; O'Laughlin, S; Komp, DM. Histiocytes in familial and infection-induced/idiopathic hemophagocytic syndromes may exhibit phenotypic differences. Pediatric Pathology. 1992;12:51-66.
(1992)
Abstract
West, AB; Buckley, PJ. Mantle zone lymphoma in a gastric glomus tumor. Cancer. 1992;70:2246-2249.
(1992)
Abstract
Buckley, PJ. Phenotypic subpopulations of macrophages and dendritic cells in human spleen. Scanning Microscopy. 1991;5:147-157.
(1991)
Abstract
Eisen, RN; Buckley, PJ; Rosai, J. Immunophenotypic characterization of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease). Seminars in Diagnostic Pathology. 1990;7:74-82.
(1990)
Abstract
Sieber, SC; Lopez, V; Rosai, J; Buckley, PJ. Primary tumor of spleen with morphologic features of malignant fibrous histiocytoma. Immunohistochemical evidence for a macrophage origin. American Journal of Surgical Pathology. 1990;14:1061-1070.
(1990)
Abstract
Komp, DM; Buckley, PJ; McNamara, J; van Hoff, J. Soluble interleukin-2 receptor in hemophagocytic histiocytoses: searching for markers of disease activity. Pediatric Hematology and Oncology. 1989;6:253-264.
(1989)
Abstract
Keller, MS; Buckley, PJ. Sonographic tissue pattern in neuroblastoma. American Journal of Roentgenology. 1988;150:693.
(1988)
Abstract
Buckley, PJ; Smith, MR; Braverman, MF; Dickson, SA. Human spleen contains phenotypic subsets of macrophages and dendritic cells that occupy discrete microanatomic locations. American Journal of Pathology. 1987;128:505-520.
(1987)
Abstract
Gerald, WL; Sussman, J; Buckley, PJ. The immunologic approach to analysis of malignant lymphoma. Mantle zone lymphoma of the ileocecal region. Journal of Clinical Gastroenterology. 1987;9:588-598.
(1987)
Abstract
Buckley, PJ; Dickson, SA; Walker, WS. Human splenic sinusoidal lining cells express antigens associated with monocytes, macrophages, endothelial cells, and T lymphocytes. Journal of Immunology. 1985;134:2310-2315.
(1985)
Abstract
Fitch, S; Parvey, LS; Wilimas, J; Buckley, PJ; Webber, BL. Developmental cystic renal neoplasms in children. Diagnostic imaging characteristics. Computerized Radiology. 1985;9:149-158.
(1985)
Abstract
Furman, WL; Buckley, PJ; Green, AA; Stokes, DC; Chien, LT. Thymoma and myasthenia gravis in a 4-year-old child. Case report and review of the literature. Cancer. 1985;56:2703-2706.
(1985)
Abstract
Buckley, PJ; Beelen, RH; Burns, J; Beard, CM; Dickson, SA; Walker, WS. Isolation of human splenic macrophages and lymphocytes by countercurrent centrifugal elutriation. Journal of Immunological Methods. 1984;66:201-217.
(1984)
Abstract
Buckley, PJ; Dickson, SA. Monoclonal antibodies to T-helper/inducer and T-suppressor/cytotoxic lymphocyte subsets recognize antigens on splenic sinusoidal lining cells. American Journal of Clinical Pathology. 1984;82:167-172.
(1984)
Abstract
Walker, WS; Beelen, RH; Buckley, PJ; Melvin, SL; Yen, SE. Some fixation reagents reduce or abolish the detectability of Ia-antigen and HLA-DR on cells. Journal of Immunological Methods. 1984;67:89-99.
(1984)
Abstract
Leveston, SA; McKeel, DW; Buckley, PJ; Deschryver, K; Greider, MH; Jaffe, BM; Daughaday, WH. Acromegaly and Cushing's syndrome associated with a foregut carcinoid tumor. Journal of Clinical Endocrinology and Metabolism. 1981;53:682-689.
(1981)
Abstract
Tanner, DD; Buckley, PJ; Hong, R; Shearer, WT. Fatal cytomegalovirus bronchiolitis in a patient with Nezelof's syndrome. Pediatrics. 1980;65:98-102.
(1980)
Abstract
Buckley, PJ; Wedner, HJ. Measurement of the DNA synthetic capacity of activated lymphocytes: nucleotide triphosphate incorporation by permeabilized cells. Journal of Immunology. 1978;120:1930-1940.
(1978)
Abstract
Buckley, PJ; Wedner, HJ. Variation in DNA and RNA synthetic responses during activation of lymphocytes from inbred strains of mice. Journal of Immunology. 1977;119:9-18.
(1977)
Abstract
Howe, CC; Buckley, PJ; Carlson, KM; Kozinski, AW. Multiple and specific initiation of T4 DNA replication. Journal of Virology. 1973;12:130-148.
(1973)
Abstract
Buckley, PJ; Kosturko, LD; Kozinski, AW. In vivo production of an RNA-DNA copolymer after infection of Escherichia coli by bacteriophage T4. Proceedings of the National Academy of Sciences of USA. 1972;69:3165-3169.
(1972)
Abstract
Krishnamurthi, VS; Buckley, PJ; Duerre, JA. Pigment formation from L-tryptophan by a particulate fraction from an Achromobacter species. Archives of Biochemistry and Biophysics. 1969;130:636-645.
(1969)
Abstract
Duerre, JA; Buckley, PJ. Pigment production from tryptophan by an Achromobacter species. Journal of Bacteriology. 1965;90:1686-1691.
(1965)
Abstract
