Physicians

Department / Division
Medicine / Medicine - Cardiology

Address
DUMC 3850
Durham, NC 27710

Appointment Telephone
919-681-5816

Office Telephone
919-668-8959

Fax Telephone
919-668-8665

Training

• MD, Duke University School of Medicine, 1989-1993

Residency

• Internal Medicine, Duke University Medical Center, 1993-1996
• Cardiology, Cleveland Clinic Foundation, 1996-1999

Other Training

• MHS, Duke University School of Medicine, 2001

Clinical Interests
Coronary artery disease, hypertension, hyperlipidemia, peripheral arterial disease

Research Interests
1) Acute Coronary Syndromes
- Risk Stratification in the Emergency Department
- Optimal Use of Anti-Platelet and Anti-Thrombotic Therapies
- Timing of Treatment with Platelet GP IIb/IIIa Inhibitors
- Early Invasive Management Treatment Strategies

2) Reperfusion Strategies for Acute Myocardial Infarction
- Using Biomarker Arrays to Evaluate Therapies in Phase II Trials
- Combination Reperfusion Therapy with Partial-Dose Fibrinolytics and GP IIb/IIIa Inhibitors

Industry Relationships and Collaborations (What's this?)

This physician (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.

• AstraZeneca
• BOLT International
• Bristol-Myers Squibb
• Clearview Health Partners
• Elsevier
• GlaxoSmithKline
• Merck & Co. USA (not assoc'd with Merck KGaA)
• Novartis
• Ortho-McNeil Pharmceutical (Johnson & Johnson)
• Sanofi-Aventis

Representative Publications
4. Roe MT, Ohman EM, Maas ACP, Christenson RH, Mahaffey KW, Granger CB, Harrington RA, Califf RM, Krucoff MW. Shifting the open artery hypothesis downstream: the quest for optimal reperfusion. Journal of the American College of Cardiology 2001;37:9-18. (2001)

1. Roe MT, Treatment Strategies for Microvascular Dysfunction Following Acute Myocardial Infarction. Current Cardiology Reports 2000; 2:405 - 410. (2000)

2. Roe MT, Giugliano RP, Harrington RA, Gibson CM, Strony J, Kitt MM, Califf RM, Braunwald E. Combination reperfusion therapy for acute myocardial infarction with eptifibatide and teneteplase. Design and methodology of the (INTEGRILIN and tenecteplase in acute myocardial infarction) INTEGRITI trial. Heart Drug 2000;1:5-13. (2000)

3. Roe MT, Harrington RA, Prosper DM, Bhatt DL, Lincoff AM, Simoons ML, Akkerhuis M, Ohman EM, Pieper KS, Kitt MM, Vahanian A, Ruzyllo W, Karsch K, Califf RM, Topol EJ. Clinical and therapeutic profile of patients with acute coronary syndromes who do not have significant coronary artery disease. Circulation 2000;102:1101-1106. (2000)