Physicians

Director, Adult Cardiothoracic Anesthesia and Critical Care Fellowship
Director, Fellowship Education Program

Department / Division
Anesthesiology / Anesthesiology-Cardiac Division

Address
DUMC 3094
Durham, NC 27710

Office Telephone
919-681-5046

Fax Telephone
919-681-8993

Training

• MD, CM, McGill University Faculty of Medicine (Canada), 1983

Residency

• Family Medicine, Dalhousie Medical School Affiliated Health Care Centers (Canada), 1984-1985
• Anesthesia, Dalhousie University Medical Schools Affiliated Health Care Centers (Canada), 1991

Fellowship

• Cardiac Anesthesia, Duke University Medical Center, 1994-1996

Other Training

• Fellow, American Society of Echocardiography

Clinical Interests
General, cardiothoracic anesthesiology

Research Interests
My research interests are in the area of Cardiothoracic Anesthesiology. The main focus of my research is towards the understanding and prevention of acute kidney injury after cardiac and other major surgeries. Secondary interests include the study of analgesic strategies after cardiothoracic surgical procedures, performance of clinical trials, and perioperative transfusion and hemostasis.

Industry Relationships and Collaborations (What's this?)

This faculty member has no reported relationships with industry.

Representative Publications
Shaw, AD; Stafford-Smith, M; White, WD; Phillips-Bute, B; Swaminathan, M; Milano, C; Welsby, IJ; Aronson, S; Mathew, JP; Peterson, ED; Newman, MF. The effect of aprotinin on outcome after coronary-artery bypass grafting. New England Journal of Medicine. 2008;358:784-793. (2008) Abstract

Stafford-Smith, M; Patel, UD; Phillips-Bute, BG; Shaw, AD; Swaminathan, M. Acute kidney injury and chronic kidney disease after cardiac surgery. Advances in Chronic Kidney Disease. 2008;15:257-277. (2008) Abstract

Swaminathan, M; Shaw, AD; Phillips-Bute, BG; McGugan-Clark, PL; Archer, LE; Talbert, S; Milano, CA; Patel, UD; Stafford-Smith, M. Trends in acute renal failure associated with coronary artery bypass graft surgery in the United States. Critical Care Medicine. 2007;35:2286-2291. (2007) Abstract

Stafford-Smith, M; Lefrak, EA; Qazi, AG; Welsby, IJ; Barber, L; Hoeft, A; Dorenbaum, A; Mathias, J; Rochon, JJ; Newman, MF; Members of the Global Perioperative Research Organization. Efficacy and safety of heparinase I versus protamine in patients undergoing coronary artery bypass grafting with and without cardiopulmonary bypass. Anesthesiology. 2005;103:229-240. (2005) Abstract

Stafford-Smith, M; Podgoreanu, M; Swaminathan, M; Phillips-Bute, B; Mathew, JP; Hauser, EH; Winn, MP; Milano, C; Nielsen, DM; Smith, M; Morris, R; Newman, MF; Schwinn, DA; Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team. Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery. American Journal of Kidney Diseases. 2005;45:519-530. (2005) Abstract

Welsby, IJ; Newman, MF; Phillips-Bute, B; Messier, RH; Kakkis, ED; Stafford-Smith, M. Hemodynamic changes after protamine administration: association with mortality after coronary artery bypass surgery. Anesthesiology. 2005;102:308-314. (2005) Abstract

Welsby, IJ; Podgoreanu, MV; Phillips-Bute, B; Mathew, JP; Smith, PK; Newman, MF; Schwinn, DA; Stafford-Smith, M; Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team. Genetic factors contribute to bleeding after cardiac surgery. Journal of Thrombosis and Haemostasis. 2005;3:1206-1212. (2005) Abstract