Manal F. Abdelmalek, MD, MPH
Department / Division
Medicine /
Medicine - Gastroenterology
Address
DUMC 3913
Durham, NC 27710
Appointment Telephone
919-684-6437
Office Telephone
919-684-3262
Fax Telephone
919-684-8857
- MD, University of Missouri–Kansas City School of Medicine, 1992
- Internal Medicine, Mayo Clinic (Minnesota), 1992-1995
- Gastroenterology-Hepatology, Mayo Clinic (Arizona, Minnesota), 1995-1998
- MPH, University of Florida, 2004
Clinical Interests
Obesity-related liver disease and the metabolic syndrome of insulin resistance, including evaluation of new treatment options and the impact of fatty liver from a public health perspective
Research Interests
My research interests include metabolic liver disease, particularly obesity-related liver disease and its association with complications of the insulin resistance syndrome. I am interested in studying the clinical, environmental, and genetic risk factors for nonalcoholic fatty liver disease, new therapeutic options for treatment, and evaluating the impact of NAFLD from a public health perspective.
This faculty member has no reported relationships with industry.
Representative Publications
Abdelmalek, MF; Diehl, AM. De novo nonalcoholic fatty liver disease after liver transplantation. Liver Transplantation. 2007;13:788-790.
(2007)
Abstract
Abdelmalek, MF; Liu, C; Valentine, JF. Successful treatment of chronic hepatitis C with pegylated interferon, ribavirin, and infliximab in a patient with Crohn's disease. American Journal of Gastroenterology. 2007;102:1333-1334.
(2007)
Abstract
Abdelmalek, MF; Liu, C; Shuster, J; Nelson, DR; Asal, NR. Familial aggregation of insulin resistance in first-degree relatives of patients with nonalcoholic fatty liver disease. Clinical Gastroenterology and Hepatology. 2006;4:1162-1169.
(2006)
Abstract
Firpi, RJ; Zhu, H; Morelli, G; Abdelmalek, MF; Soldevila-Pico, C; Machicao, VI; Cabrera, R; Reed, AI; Liu, C; Nelson, DR. Cyclosporine suppresses hepatitis C virus in vitro and increases the chance of a sustained virological response after liver transplantation. Liver Transplantation. 2006;12:51-57.
(2006)
Abstract
Machicao, VI; Srinivas, TR; Hemming, AW; Soldevila-Pico, C; Firpi, RJ; Reed, AI; Morelli, GJ; Nelson, DR; Abdelmalek, MF. Impact of implementation of the MELD scoring system on the prevalence and incidence of chronic renal disease following liver transplantation. Liver Transplantation. 2006;12:754-761.
(2006)
Abstract
Lucey, MR; Abdelmalek, MF; Gagliardi, R; Granger, D; Holt, C; Kam, I; Klintmalm, G; Langnas, A; Shetty, K; Tzakis, A; Woodle, ES. A comparison of tacrolimus and cyclosporine in liver transplantation: effects on renal function and cardiovascular risk status. American Journal of Transplantation. 2005;5:1111-1119.
(2005)
Abstract
Abdelmalek, MF; Firpi, RJ; Soldevila-Pico, C; Reed, AI; Hemming, AW; Liu, C; Crawford, JM; Davis, GL; Nelson, DR. Sustained viral response to interferon and ribavirin in liver transplant recipients with recurrent hepatitis C. Liver Transplantation. 2004;10:199-207.
(2004)
Abstract
Firpi, RJ; Abdelmalek, MF; Soldevila-Pico, C; Cabrera, R; Shuster, JJ; Theriaque, D; Reed, AI; Hemming, AW; Liu, C; Crawford, JM; Nelson, DR. One-year protocol liver biopsy can stratify fibrosis progression in liver transplant recipients with recurrent hepatitis C infection. Liver Transplantation. 2004;10:1240-1247.
(2004)
Abstract
Abdelmalek, MF; Pasha, TM; Zein, NN; Persing, DH; Wiesner, RH; Douglas, DD. Subclinical reactivation of hepatitis B virus in liver transplant recipients with past exposure. Liver Transplantation. 2003;9:1253-1257.
(2003)
Abstract
Firpi, RJ; Abdelmalek, MF; Soldevila-Pico, C; Reed, A; Hemming, A; Howard, R; Van Der Werf, W; Lauwers, G; Liu, C; Crawford, JM; Davis, GL; Nelson, DR. Combination of interferon alfa-2b and ribavirin in liver transplant recipients with histological recurrent hepatitis C. Liver Transplantation. 2002;8:1000-1006.
(2002)
Abstract
Abdelmalek, MF; Angulo, P; Jorgensen, RA; Sylvestre, PB; Lindor, KD. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. American Journal of Gastroenterology. 2001;96:2711-2717.
(2001)
Abstract
Nelson, DR; Soldevila-Pico, C; Reed, A; Abdelmalek, MF; Hemming, AW; Van der Werf, WJ; Howard, R; Davis, GL. Anti-interleukin-2 receptor therapy in combination with mycophenolate mofetil is associated with more severe hepatitis C recurrence after liver transplantation. Liver Transplantation. 2001;7:1064-1070.
(2001)
Abstract
Abdelmalek, MF; Harrison, ME; Gross, JB; Poterucha, JJ; Gossard, AA; Spivey, JR; Rakela, J; Lindor, KD. Treatment of chronic hepatitis C with interferon with or without ursodeoxycholic acid: a randomized prospective trial. Journal of Clinical Gastroenterology. 1998;26:130-134.
(1998)
Abstract
