Department / Division:
Surgery / General Surgery

Address:
Duke Health Center at North Duke Street
3116 North Duke Street
Durham, NC 27704

Appointment Telephone:
919-660-2244

Office Telephone:
919-660-2244

Fax Telephone:
919-660-2255

• MD, Duke University School of Medicine, 1993

• General Surgery, University Hospitals of Michigan, 1993-2000

Clinical Interests:
Benign and malignant diseases of the breast; sentinel lymph-node mapping; neoadjuvant therapy for breast cancer; laparoscopic abdominal surgery

Research Interests:
My primary research interest is clinical trials which seek to define novel means to treat patients with breast cancer.  I have previously worked with the American College of Surgeons Oncology Group as a Medical Officer and continue to actively participate in translational and cancer clinical trials.  I also work collaboratively with several basic science researchers within Duke University to support innovative breast cancer therapeutics.

Representative Publications:
Posther KE, McCall LM, Blumencranz PW, Burak WE Jr, Beitsch PD, Hansen NM, Morrow M, Wilke LG, Herndon JE 2nd, Hunt KK, Giuliano AE. Sentinel node skills verification and surgeon performance: data from a multicenter clinical trial for early-stage breast cancer. Ann Surg. 2005 Oct;242(4):593-9; discussion 599-602. (2005) Abstract

Bean GR, Scott V, Yee L, Ratliff-Daniel B, Troch MM, Seo P, Bowie ML, Marcom PK, Slade J, Kimler BF, Fabian CJ, Zalles CM, Broadwater G, Baker JC Jr, Wilke LG, Seewaldt VL. Retinoic acid receptor-beta2 promoter methylation in random periareolar fine needle aspiration. Cancer Epidemiol Biomarkers Prev. 2005 Apr;14(4):790-8. (2005) Abstract

Wilke LG. Training and mentoring surgeons in lymphatic mapping. Semin Oncol. 2004 Jun;31(3):333-7. (2004) Abstract

Wilke LG, Giuliano A. Sentinel lymph node biopsy in patients with early-stage breast cancer: status of the National Clinical Trials. Surg Clin North Am. 2003 Aug;83(4):901-10. (2003) Abstract