Department / Division:
Medicine / Nephrology

Address:
DUMC 3075
Durham, NC 27710

Appointment Telephone:
919-668-7630

Office Telephone:
919-660-6626

Fax Telephone:
919-660-8802

• MD, Harvard Medical School (Massachusetts), 1979

• Internal Medicine, Montefiore Hospital and Medical Center (New York), 1979-1982

• General Internal Medicine, Duke University Medical Center, 1982-1983

• MHS, Biometry, Duke University, 1994

Clinical Interests:
Hypertension, genetic hypertension, salt-sensitive hypertension, dietary treatment of high blood pressure, lifestyle modification, cardiovascular risk reduction

Research Interests:
Dr. Svetkey is the Director of the Duke Hypertension Center, and Director of Clinical Research at the Sarah W. Stedman Nutrition and Metabolism Center. She has over 20 years of experience in the investigation of human hypertension and related areas, such as obesity and kidney disease.  Her research focuses on 1) dietary influences on blood pressure; 2) non-pharmacologic interventions for preventing and treating hypertension; 3) genetics of hypertension; 4) interventions for sustained weight control; 5) metabolic effects of obesity and weight loss; 6) effect of chronic kidney disease on blood pressure and blood pressure-related outcomes; 7) patient and physician interventions for improving blood pressure control; and 8)  racial disparities in blood pressure control, an area that interacts with several of the other areas listed above.

Representative Publications:
41. Svetkey LP, Stevens VJ, Brantley PJ, Appel LJ, Hollis JF, Loria C, Vollmer WM, Gullion CM, Funk K,  Smith P, Samuel-Hodge C,  Myers V, Lien LF, Laferriere D, Kennedy B,  Jerome GJ,  Heinith F, Harsha D, Evans P, Erlinger T, Dalcin AT, Coughlin J, Charleston J, Champagne CM, Bauck A, Ard JD, Aicher K for the Weight Loss Maintenance Collaborative Research Group. Comparison of Strategies for Sustaining Weight Loss: Main Results of the Weight Loss Maintenance Randomized Trial. JAMA. In Press. (2008)

Svetkey LP, Harsha DW, Vollmer WM, Stevens VJ, Obarzanek E, Elmer PJ, Lin PH, Champagne C, Simons-Morton DG, Aickin M, Proschan MA, Appel LJ. Premier: a clinical trial of comprehensive lifestyle modification for blood pressure control: rationale, design and baseline characteristics. Ann Epidemiol. 2003 Jul;13(6):462-71. (2003) Abstract

Ard JD, Carter-Edwards L, Svetkey LP. A new model for developing and executing culturally appropriate behavior modification clinical trials for African Americans. Ethn Dis. 2003 Spring;13(2):279-85. (2003) Abstract

Appel LJ, Champagne CM, Harsha DW, Cooper LS, Obarzanek E, Elmer PJ, Stevens VJ, Vollmer WM, Lin PH, Svetkey LP, Stedman SW, Young DR, . Effects of comprehensive lifestyle modification on blood pressure control: main results of the PREMIER clinical trial. JAMA. 2003 Apr 23-30;289(16):2083-93. (2003) Abstract

Carter-Edwards L, Fisher JT, Vaughn BJ, Svetkey LP. Church rosters: is this a viable mechanism for effectively recruiting African Americans for a community-based survey? Ethn Health. 2002 Feb;7(1):41-55. (2002) Abstract

Svetkey LP, Moore TJ, Simons-Morton DG, Appel LJ, Bray GA, Sacks FM, Ard JD, Mortensen RM, Mitchell SR, Conlin PR, Kesari M, . Angiotensinogen genotype and blood pressure response in the Dietary Approaches to Stop Hypertension (DASH) study. J Hypertens. 2001 Nov;19(11):1949-56. (2001) Abstract

Sacks FM, Svetkey LP, Vollmer WM, Appel LJ, Bray GA, Harsha D, Obarzanek E, Conlin PR, Miller ER III, Simons-Morton DG, Karanja N, Lin P-H for the DASH-Sodium Collaborative Research Group. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. N Engl J Med 2001;344:3-10. (2001)

Sacks FM, Svetkey LP, Vollmer WM, Appel LJ, Bray GA, Harsha D, Obarzanek E, Conlin PR, Miller ER 3rd, Simons-Morton DG, Karanja N, Lin PH, . Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group. N Engl J Med. 2001 Jan 4;344(1):3-10. (2001) Abstract

Svetkey LP, Simons-Morton D, Vollmer WM, Appel LJ, Conlin PR, Ryan DH, Ard J, Kennedy BM. Effects of dietary patterns on blood pressure: subgroup analysis of the Dietary Approaches to Stop Hypertension (DASH) randomized clinical trial. Arch Intern Med. 1999 Feb 8;159(3):285-93. (1999) Abstract

Svetkey LP, Chen Y-T, McKeown SP, Preis L, Wilson AF. Preliminary evidence of linkage of salt sensitivity in African Americans to the beta2-adrenergic receptor gene. Hypertension 1997;29:918-922. (1997)

Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, Bray GA, Vogt TM, Cutler JA, Simons-Morton D, Lin P-H, Karanja N, Windhauser WM, McCullough M, Swain J, Steele P, Evans MA, Miller ER, Harsha DW, for the DASH Collaborative Research Group. The effect of dietary patterns on blood pressure: Results from the DASH clinical trial. N Eng J Med 1997;336:1117-1124. (1997)

Svetkey LP, George LK, Burchett BM, Morgan PA, Cohen HJ, Blazer DG. Black/white differences in hypertension in the elderly: An epidemiologic analysis in central North Carolina. Am J of Epidemiology 1993;137:64-73. (1993)