Laura M. DeCastro, MD
Department / Division
Medicine /
Medicine - Hematology
Address
DUMC 3939
Durham, NC 27710
Appointment Telephone
919-660-4363
Office Telephone
919-684-6464
Fax Telephone
919-681-6174
- MD, Autonomous University of Santo Domingo (Dominican Republic), 1986
- Internal Medicine, Montefiore Medical Center (New York), 1992-1995
- Hematology-Oncology, Yale University (Connecticut), 1995-1998
Clinical Interests
Internal medicine; general adult hematology; hematological problems during pregnancy; anemias, including iron and B12 deficiencies and hemolytic anemias; hemoglobinopathies, particularly sickle cell and thalassemias; myeloproliferatic disorders and chronic leukemias (CML, CLL)
Research Interests
Dr. De Castro is an assistant professor of medicine with the Division of Hematology in the Department of Medicine at Duke University. She is the clinical director of the adult comprehensive sickle cell clinic. Her translational research projects involve the evaluation of sickle red cell adhesion to laminin and its pathophysiological significance. In, addition, she has been the PI of more than 10 NIH or industry sponsored clinical studies on SCD and she is currently the Duke/UNC Sickle Cell Scholar, funded primarily through the Duke/UNC Sickle Cell Center.
This faculty member has no reported relationships with industry.
Representative Publications
Edwards, CL; Scales, MT; Loughlin, C; Bennett, GG; Harris-Peterson, S; De Castro, LM; Whitworth, E; Abrams, M; Feliu, M; Johnson, S; Wood, M; Harrison, O; Killough, A. A brief review of the pathophysiology, associated pain, and psychosocial issues in sickle cell disease. International Journal of Behavioral Medicine. 2005;12:171-179.
(2005)
Abstract
Zen, Q; Batchvarova, M; Twyman, CA; Eyler, CE; Qiu, H; De Castro, LM; Telen, MJ. B-CAM/LU expression and the role of B-CAM/LU activation in binding of low- and high-density red cells to laminin in sickle cell disease. American Journal of Hematology. 2004;75:63-72.
(2004)
Abstract
