Physicians

Director, Duke Stroke Center

Department / Division
Medicine / Medicine-Neurology

Address
DUMC 3651
Durham, NC 27710

Appointment Telephone
919-668-7600

Office Telephone
919-684-3801

Fax Telephone
919-684-6514

Training

• MD, Mount Sinai School of Medicine of New York University, 1981

Residency

• Neurology, Mount Sinai Medical Center (New York), 1981-1985

Fellowship

• Cerebrovascular Research, Duke University Medical Center, 1985-1987

Other Training

• Board Certifications, Neurology and Vascular Neurology

Clinical Interests
Stroke, cerebrovascular disease, TIAs

Research Interests
General Research Focus: Cerebrovascular Disease/Stroke. Research efforts have involved several aspects of cerebrovascular disease. In the laboratory, work has centered on developing an understanding of the mechanisms underlying pharmacological modulation of motor recovery after injury to the cerebral cortex and has led to several clinical studies in patients with stroke and traumatic brain injury. Research in stroke has also focused on health policy issues related to the use of carotid endarterectomy and optimization of stroke prevention strategies. Research involving new therapies for acute stroke has been carried out through clinical trials. Current focus is on identifying genes associated with small-vessel type stroke.

Specific Approaches: Laboratory Research: Studies of recovery after sensorimotor cortex injury have focused on measurement of neurobehavioral recovery as influenced by systemically administered drugs modulating the activities of specific central neurotransmitters. This work has involved behavioral measures, stereotactic lesioning, basic neurochemistry, cerebral microdialysis, and immunocytochemistry. Health Policy Research: Work has focused on clinical health policy related to cerebrovascular disease carried out in conjunction with the Center for Clinical Health Policy Research. These studies have centered on the utilization of carotid endarterectomy and the optimization of secondary and tertiary stroke prevention with an emphasis on outcome measures.

Clinical Trials: Principal investigator at Duke for several stroke acute treatment trials including studies of GM1-ganglioside and several neuroprotective drugs including CGS-19755 (Selfotel), Eliprodil, and a glycine receptor anatagonist. Principal or co-investigator at Duke for several stroke prevention trials including the NIH-supported study of carotid angioplasty and stenting as compared with carotid endarterectomy (CREST), RESPECT (PFO closure), PROfESS (antiplatelet drugs and angiotensin receptor blocker). In addition, principal investigator for NIH-supported studies related to poststroke recovery and steering committee for SPARCL (statin for secondary stroke prevention).

Special Expertise: Effects of drugs on recovery after stroke and brain injury
Neuroplasticity and behavioral recovery after brain injury
Stroke trial design and outcomes measures
Carotid endarterectomy/ angioplasty-stenting
Stroke prevention (primary and secondary)
Stroke-related health policy and outcomes


Key Words: Neurorehabilitation, stroke, cerebrovascular disease, neurobehavior, carotid endarterectomy, angioplasty, health services, prevention, outcomes

Industry Relationships and Collaborations (What's this?)

This faculty member has no reported relationships with industry.

Representative Publications
Martin, KD; Naert, L; Goldstein, LB; Kasl, S; Molinaro, AM; Lichtman, JH. Comparing the use of diagnostic imaging and receipt of carotid endarterectomy in elderly black and white stroke patients. Journal of Stroke and Cerebrovascular Diseases. 2012;21:600-606. (2012) Abstract

Zhang, L; Harrison, JK; Goldstein, LB. Echocardiography for the detection of cardiac sources of embolism in patients with stroke or transient ischemic attack. Journal of Stroke and Cerebrovascular Diseases. 2012;21:577-582. (2012) Abstract

Albers, GW; Goldstein, LB; Hess, DC; Wechsler, LR; Furie, KL; Gorelick, PB; Hurn, P; Liebeskind, DS; Nogueira, RG; Saver, JL; STAIR VII Consortium. Stroke Treatment Academic Industry Roundtable (STAIR) recommendations for maximizing the use of intravenous thrombolytics and expanding treatment options with intra-arterial and neuroprotective therapies. Stroke. 2011;42:2645-2650. (2011) Abstract

Brainin, M; Norrving, B; Sunnerhagen, KS; Goldstein, LB; Cramer, SC; Donnan, GA; Duncan, PW; Francisco, G; Good, D; Graham, G; Kissela, BM; Olver, J; Ward, A; Wissel, J; Zorowitz, R; International PSS Disability Study Group. Poststroke chronic disease management: towards improved identification and interventions for poststroke spasticity-related complications. International Journal of Stroke. 2011;6:42-46. (2011) Abstract

Bushnell, CD; Olson, DM; Zhao, X; Pan, W; Zimmer, LO; Goldstein, LB; Alberts, MJ; Fagan, SC; Fonarow, GC; Johnston, SC; Kidwell, C; Labresh, KA; Ovbiagele, B; Schwamm, L; Peterson, ED; AVAIL Investigators. Secondary preventive medication persistence and adherence 1 year after stroke. Neurology. 2011;77:1182-1190. (2011) Abstract

Callahan, A; Amarenco, P; Goldstein, LB; Sillesen, H; Messig, M; Samsa, GP; Altafullah, I; Ledbetter, LY; MacLeod, MJ; Scott, R; Hennerici, M; Zivin, JA; Welch, KM; SPARCL Investigators. Risk of stroke and cardiovascular events after ischemic stroke or transient ischemic attack in patients with type 2 diabetes or metabolic syndrome: secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. Archives of Neurology. 2011;68:1245-1251. (2011) Abstract

Cohen, DJ; Stolker, JM; Wang, K; Magnuson, EA; Clark, WM; Demaerschalk, BM; Sam, AD; Elmore, JR; Weaver, FA; Aronow, HD; Goldstein, LB; Roubin, GS; Howard, G; Brott, TG; CREST Investigators. Health-related quality of life after carotid stenting versus carotid endarterectomy: results from CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial). Journal of the American College of Cardiology. 2011;58:1557-1565. (2011) Abstract

El Husseini, N; Shea, KJ; Goldstein, LB. Concerns for the reliability and validity of the National Stroke Project Stroke Severity Scale. Cerebrovascular Diseases. 2011;32:426-430. (2011) Abstract

Goldstein, LB. Left atrial enlargement: a cause of stroke?. CMAJ. 2011;183:1129-1130. (2011) Abstract

Goldstein, LB. Novel platelet antiaggregants and the changing landscape of stroke prevention. Lancet Neurology. 2011;10:678-680. (2011) Abstract

Goldstein, LB. Statins after intracerebral hemorrhage: to treat or not to treat. Archives of Neurology. 2011;68:565-566. (2011) Abstract

Goldstein, LB. Stroke: Organizing the disorganized: improving TIA patient care. Nature Reviews. Neurology. 2011;7:190-192. (2011) Abstract

Goldstein, LB; Bushnell, CD; Adams, RJ; Appel, LJ; Braun, LT; Chaturvedi, S; Creager, MA; Culebras, A; Eckel, RH; Hart, RG; Hinchey, JA; Howard, VJ; Jauch, EC; Levine, SR; Meschia, JF; Moore, WS; Nixon, JV; Pearson, TA; American Heart Association Stroke Council, ; Council on Cardiovascular Nursing, ; Council on Epidemiology and Prevention, ; Council for High Blood Pressure Research,, ; Council on Peripheral Vascular Disease, and Interdisciplinary Council on Quality of Care and Outcomes Research. Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42:517-584. (2011) Abstract

Goldstein, LB; El Husseini, N. [Neurology and cardiology: points of contact]. Revista Espanola de Cardiologia. 2011;64:319-327. (2011) Abstract

Goldstein, LB; Whitsel, LP; Meltzer, N; Schoeberl, M; Birnbaum, J; Nelson, S; Gardner, TJ; Yancy, CW; Gibbons, RJ; Sacco, RL; Hiratzka, L; American Heart Association (AHA) Advocacy Coordinating Committee, ; Council on Cardiovascular Nursing, AHA, ; Council on the Kidney in Cardiovascular Disease, AHA, ; Council on Cardiovascular Radiology and Intervention, AHA, ; Council on Cardiovascular Surgery and Anesthesia, AHA, ; Council on Clinical Cardiology, AHA, ; Council on Cardiovascular Disease in the Young, AHA, ; Council on Cardiopulmonary, Critical Care, Perioperative, and Resuscitation, AHA, ; Council on Peripheral Vascular Disease, AHA, ; Council on Arteriosclerosis, Thrombosis and Vascular Biology, AHA, ; Council on Epidemiology and Prevention, AHA, ; Council on Nutrition, Physical Activ. . . American Heart Association and nonprofit advocacy: past, present, and future. A policy recommendation from the American Heart Association. Circulation. 2011;123:816-832. (2011) Abstract

Hegland, D; Piccini, JP; Goldstein, LB; Daubert, JP. Cerebral magnetic resonance findings in asymptomatic patients after atrial fibrillation catheter ablation: cause for alarm or further study?. Journal of Cardiovascular Electrophysiology. 2011;22:969-972. (2011) Abstract

Lichtman, JH; Jones, SB; Leifheit-Limson, EC; Wang, Y; Goldstein, LB. 30-day mortality and readmission after hemorrhagic stroke among Medicare beneficiaries in Joint Commission primary stroke center-certified and noncertified hospitals. Stroke. 2011;42:3387-3391. (2011) Abstract

Lichtman, JH; Jones, SB; Wang, Y; Watanabe, E; Leifheit-Limson, E; Goldstein, LB. Outcomes after ischemic stroke for hospitals with and without Joint Commission-certified primary stroke centers. Neurology. 2011;76:1976-1982. (2011) Abstract

Lichtman, JH; Naert, L; Allen, NB; Watanabe, E; Jones, SB; Barry, LC; Bravata, DM; Goldstein, LB. Use of antithrombotic medications among elderly ischemic stroke patients. Circulation: Cardiovascular Quality and Outcomes. 2011;4:30-38. (2011) Abstract

Plant, SR; Samsa, GP; Shah, SH; Goldstein, LB. Exploration of a hypothesized independent association of a common 9p21.3 gene variant and ischemic stroke in patients with and without angiographic coronary artery disease. Cerebrovascular Diseases. 2011;31:117-122. (2011) Abstract

Rodriguez, D; Cox, M; Zimmer, LO; Olson, DM; Goldstein, LB; Drew, L; Peterson, ED; Bushnell, CD; AVAIL Investigators. Similar secondary stroke prevention and medication persistence rates among rural and urban patients. Journal of Rural Health. 2011;27:401-408. (2011) Abstract

Silver, FL; Mackey, A; Clark, WM; Brooks, W; Timaran, CH; Chiu, D; Goldstein, LB; Meschia, JF; Ferguson, RD; Moore, WS; Howard, G; Brott, TG; CREST Investigators. Safety of stenting and endarterectomy by symptomatic status in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). Stroke. 2011;42:675-680. (2011) Abstract

Allen, NB; Holford, TR; Bracken, MB; Goldstein, LB; Howard, G; Wang, Y; Lichtman, JH. Geographic variation in one-year recurrent ischemic stroke rates for elderly Medicare beneficiaries in the USA. Neuroepidemiology. 2010;34:123-129. (2010) Abstract

Allen, NB; Holford, TR; Bracken, MB; Goldstein, LB; Howard, G; Wang, Y; Lichtman, JH. Trends in one-year recurrent ischemic stroke among the elderly in the USA: 1994-2002. Cerebrovascular Diseases. 2010;30:525-532. (2010) Abstract

Amarenco, P; Goldstein, LB; Sillesen, H; Benavente, O; Zweifler, RM; Callahan, A; Hennerici, MG; Zivin, JA; Welch, KM; Stroke Prevention by Aggressive Reduction in Cholesterol Levels Investigators. Coronary heart disease risk in patients with stroke or transient ischemic attack and no known coronary heart disease: findings from the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. Stroke. 2010;41:426-430. (2010) Abstract

Goldstein, LB. Physical activity and the risk of stroke. Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders. 2010;10:1263-1265. (2010) Abstract

Goldstein, LB. Statewide hospital-based stroke services in North Carolina: changes over 10 years. Stroke. 2010;41:778-783. (2010) Abstract

Goldstein, LB; Rothwell, PM. Advances in prevention and health services delivery 2009. Stroke. 2010;41:e71-e73. (2010) Abstract

Hachinski, V; Donnan, GA; Gorelick, PB; Hacke, W; Cramer, SC; Kaste, M; Fisher, M; Brainin, M; Buchan, AM; Lo, EH; Skolnick, BE; Furie, KL; Hankey, GJ; Kivipelto, M; Morris, J; Rothwell, PM; Sacco, RL; Smith, SC; Wang, Y; Bryer, A; Ford, GA; Iadecola, C; Martins, SC; Saver, J; Skvortsova, V; Bayley, M; Bednar, MM; Duncan, P; Enney, L; Finklestein, S; Jones, TA; Kalra, L; Kleim, J; Nitkin, R; Teasell, R; Weiller, C; Desai, B; Goldberg, MP; Heiss, WD; Saarelma, O; Schwamm, LH; Shinohara, Y; Trivedi, B; Wahlgren, N; Wong, LK; Hakim, A; Norrving, B; Prudhomme, S; Bornstein, NM; Davis, SM; Goldstein, LB; Leys, D; Tuomilehto, J; Stroke Synergium. Stroke: working toward a prioritized world agenda. Cerebrovascular Diseases. 2010;30:127-147. (2010) Abstract

Kernan, WN; Launer, LJ; Goldstein, LB. What is the future of stroke prevention?: debate: polypill versus personalized risk factor modification. Stroke. 2010;41:S35-S38. (2010) Abstract

Krishnan, A; Lopes, RD; Alexander, JH; Becker, RC; Goldstein, LB. Antithrombotic therapy for ischemic stroke: guidelines translated for the clinician. Journal of Thrombosis and Thrombolysis. 2010;29:368-377. (2010) Abstract

Lichtman, JH; Jones, SB; Wang, Y; Watanabe, E; Allen, NB; Fayad, P; Goldstein, LB. Postendarterectomy mortality in octogenarians and nonagenarians in the USA from 1993 to 1999. Cerebrovascular Diseases. 2010;29:154-161. (2010) Abstract

Lichtman, JH; Leifheit-Limson, EC; Jones, SB; Watanabe, E; Bernheim, SM; Phipps, MS; Bhat, KR; Savage, SV; Goldstein, LB. Predictors of hospital readmission after stroke: a systematic review. Stroke. 2010;41:2525-2533. (2010) Abstract

Marquine, MJ; Attix, DK; Goldstein, LB; Samsa, GP; Payne, ME; Chelune, GJ; Steffens, DC. Differential patterns of cognitive decline in anterior and posterior white matter hyperintensity progression. Stroke. 2010;41:1946-1950. (2010) Abstract

Schwamm, L; Fayad, P; Acker, JE; Duncan, P; Fonarow, GC; Girgus, M; Goldstein, LB; Gregory, T; Kelly-Hayes, M; Sacco, RL; Saver, JL; Segrest, W; Solis, P; Yancy, CW. Translating evidence into practice: a decade of efforts by the American Heart Association/American Stroke Association to reduce death and disability due to stroke: a presidential advisory from the American Heart Association/American Stroke Association. Stroke. 2010;41:1051-1065. (2010) Abstract

Xu, H; Stamova, B; Jickling, G; Tian, Y; Zhan, X; Ander, BP; Liu, D; Turner, R; Rosand, J; Goldstein, LB; Furie, KL; Verro, P; Johnston, SC; Sharp, FR; Decarli, CS. Distinctive RNA expression profiles in blood associated with white matter hyperintensities in brain. Stroke. 2010;41:2744-2749. (2010) Abstract

Adkins, DL; Schallert, T; Goldstein, LB. Poststroke treatment: lost in translation. Stroke. 2009;40:8-9. (2009) Abstract

Allen, NB; Myers, D; Watanabe, E; Dostal, J; Sama, D; Goldstein, LB; Lichtman, JH. Utilization of intravenous tissue plasminogen activator for ischemic stroke: are there sex differences?. Cerebrovascular Diseases. 2009;27:254-258. (2009) Abstract

Amarenco, P; Benavente, O; Goldstein, LB; Callahan, A; Sillesen, H; Hennerici, MG; Gilbert, S; Rudolph, AE; Simunovic, L; Zivin, JA; Welch, KM; Stroke Prevention by Aggressive Reduction in Cholesterol Levels Investigators. Results of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial by stroke subtypes. Stroke. 2009;40:1405-1409. (2009) Abstract

Amarenco, P; Goldstein, LB; Callahan, A; Sillesen, H; Hennerici, MG; O'Neill, BJ; Rudolph, AE; Simunovic, L; Zivin, JA; Welch, KM; SPARCL Investigators. Baseline blood pressure, low- and high-density lipoproteins, and triglycerides and the risk of vascular events in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. Atherosclerosis. 2009;204:515-520. (2009) Abstract

Amarenco, P; Goldstein, LB; Messig, M; O'Neill, BJ; Callahan, A; Sillesen, H; Hennerici, MG; Zivin, JA; Welch, KM; SPARCL Investigators. Relative and cumulative effects of lipid and blood pressure control in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels trial. Stroke. 2009;40:2486-2492. (2009) Abstract

Bushnell, C; Zimmer, L; Schwamm, L; Goldstein, LB; Clapp-Channing, N; Harding, T; Drew, L; Zhao, X; Peterson, E; AVAIL registry. The Adherence eValuation After Ischemic Stroke Longitudinal (AVAIL) registry: design, rationale, and baseline patient characteristics. American Heart Journal. 2009;157:428-435.e2. (2009) Abstract

Chaturvedi, S; Zivin, J; Breazna, A; Amarenco, P; Callahan, A; Goldstein, LB; Hennerici, M; Sillesen, H; Rudolph, A; Welch, MA; SPARCL Investigators. Effect of atorvastatin in elderly patients with a recent stroke or transient ischemic attack. Neurology. 2009;72:688-694. (2009) Abstract

Frendl, DM; Strauss, DG; Underhill, BK; Goldstein, LB. Lack of impact of paramedic training and use of the cincinnati prehospital stroke scale on stroke patient identification and on-scene time. Stroke. 2009;40:754-756. (2009) Abstract

Galbreath, AD; Goldstein, LB. Dysnomia, ataxia, choreoathetosis, sensory impairment, and gait imbalance after lentiform nucleus stroke. Journal of Stroke and Cerebrovascular Diseases. 2009;18:494-496. (2009) Abstract

Gibbons, RJ; Gardner, TJ; Anderson, JL; Goldstein, LB; Meltzer, N; Weintraub, WS; Yancy, CW; American Heart Association Advocacy Coordinating Committee. The American Heart Association's principles for comparative effectiveness research: a policy statement from the American Heart Association. Circulation. 2009;119:2955-2962. (2009) Abstract

Goldstein, LB. Amphetamine trials and tribulations. Stroke. 2009;40:S133-S135. (2009) Abstract

Goldstein, LB. Clopidogrel plus aspirin in atrial fibrillation. New England Journal of Medicine. 2009;361:1313. (2009) Abstract

Goldstein, LB. Eating yourself to a stroke?. Annals of Neurology. 2009;66:129-131. (2009) Abstract

Goldstein, LB. JUPITER and the world of stroke medicine. Lancet Neurology. 2009;8:129-131. (2009) Abstract

Goldstein, LB. New data about stenting versus endarterectomy for symptomatic carotid artery stenosis. Current Treatment Options in Cardiovascular Medicine. 2009;11:232-240. (2009) Abstract

Goldstein, LB. Statins and ischemic stroke severity: cytoprotection. Current Atherosclerosis Reports. 2009;11:296-300. (2009) Abstract

Goldstein, LB. Stroke recovery and rehabilitation. Handbook of Clinical Neurology. 2009;94:1327-1337. (2009) Abstract

Goldstein, LB. The 2009 Feinberg lecture: the continuum of stroke research and policy. Stroke. 2009;40:3879-3882. (2009) Abstract

Goldstein, LB. The cart and the horse: the advancing technology of carotid artery stenting. Circulation: Cardiovascular Interventions. 2009;2:153-155. (2009) Abstract

Goldstein, LB. The complex relationship between cholesterol and brain hemorrhage. Circulation. 2009;119:2131-2133. (2009) Abstract

Goldstein, LB; Amarenco, P; Zivin, J; Messig, M; Altafullah, I; Callahan, A; Hennerici, M; MacLeod, MJ; Sillesen, H; Zweifler, R; Michael, K; Welch, A; Stroke Prevention by Aggressive Reduction in Cholesterol Levels Investigators. Statin treatment and stroke outcome in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. Stroke. 2009;40:3526-3531. (2009) Abstract

Goldstein, LB; Rothwell, PM. Advances in primary prevention and health services delivery. Stroke. 2009;40:e295-e297. (2009) Abstract

Goldstein, LB; Silberberg, M; McMiller, Y; Yaggy, SD. Stroke-related knowledge among uninsured Latino immigrants in Durham County, North Carolina. Journal of Stroke and Cerebrovascular Diseases. 2009;18:229-231. (2009) Abstract

Goldstein, LB; Suarez, JI. The quest for the "Holy Grail" of ischemic stroke cytoprotection: Statins may not be the answer. Neurology. 2009;73:2058-2059. (2009) Abstract

Lichtman, JH; Allen, NB; Wang, Y; Watanabe, E; Jones, SB; Goldstein, LB. Stroke patient outcomes in US hospitals before the start of the Joint Commission Primary Stroke Center certification program. Stroke. 2009;40:3574-3579. (2009) Abstract

Lichtman, JH; Jones, SB; Watanabe, E; Allen, NB; Wang, Y; Howard, VJ; Goldstein, LB. Elderly women have lower rates of stroke, cardiovascular events, and mortality after hospitalization for transient ischemic attack. Stroke. 2009;40:2116-2122. (2009) Abstract

Lichtman, JH; Watanabe, E; Allen, NB; Jones, SB; Dostal, J; Goldstein, LB. Hospital arrival time and intravenous t-PA use in US Academic Medical Centers, 2001-2004. Stroke. 2009;40:3845-3850. (2009) Abstract

Smith Hammond, CA; Goldstein, LB; Horner, RD; Ying, J; Gray, L; Gonzalez-Rothi, L; Bolser, DC. Predicting aspiration in patients with ischemic stroke: comparison of clinical signs and aerodynamic measures of voluntary cough. Chest. 2009;135:769-777. (2009) Abstract

Watanabe, E; Allen, NB; Dostal, J; Sama, D; Claus, EB; Goldstein, LB; Lichtman, JH. Diagnostic evaluation for patients with ischemic stroke: are there sex differences?. Cerebrovascular Diseases. 2009;27:450-455. (2009) Abstract

Abou-Donia, MB; Goldstein, LB; Bullman, S; Tu, T; Khan, WA; Dechkovskaia, AM; Abdel-Rahman, AA. Imidacloprid induces neurobehavioral deficits and increases expression of glial fibrillary acidic protein in the motor cortex and hippocampus in offspring rats following in utero exposure. Journal of Toxicology and Environmental Health Part A. 2008;71:119-130. (2008) Abstract

Adams, RJ; Albers, G; Alberts, MJ; Benavente, O; Furie, K; Goldstein, LB; Gorelick, P; Halperin, J; Harbaugh, R; Johnston, SC; Katzan, I; Kelly-Hayes, M; Kenton, EJ; Marks, M; Sacco, RL; Schwamm, LH; American Heart Association, ; American Stroke Association. Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack. Stroke. 2008;39:1647-1652. (2008) Abstract

Bushnell, CD; Lee, J; Duncan, PW; Newby, LK; Goldstein, LB. Impact of comorbidities on ischemic stroke outcomes in women. Stroke. 2008;39:2138-2140. (2008) Abstract

Gibbons, RJ; Jones, DW; Gardner, TJ; Goldstein, LB; Moller, JH; Yancy, CW; American Heart Association. The American Heart Association's 2008 Statement of Principles for Healthcare Reform. Circulation. 2008;118:2209-2218. (2008) Abstract

Goldstein, LB. 10 questions about statins and stroke. The Neurologist. 2008;14:262-264. (2008) Abstract

Goldstein, LB. Anticoagulation for atrial fibrillation in the elderly: part 1. Current Atherosclerosis Reports. 2008;10:284-285. (2008) Abstract

Goldstein, LB. Anticoagulation for atrial fibrillation in the elderly: part 2. Current Atherosclerosis Reports. 2008;10:285-286. (2008) Abstract

Goldstein, LB. How much can be gained by more systematic prevention of stroke?. International Journal of Stroke. 2008;3:266-271. (2008) Abstract

Goldstein, LB. Minocycline treatment in acute stroke. Current Atherosclerosis Reports. 2008;10:286-287. (2008) Abstract

Goldstein, LB. Primary central nervous system vasculitis: is biopsy appropriate?. Annals of Neurology. 2008;64:228. (2008) Abstract

Goldstein, LB. Reducing death and disability from stroke: the role of governmental advocacy. Stroke. 2008;39:2898-2901. (2008) Abstract

Goldstein, LB. Should angioplasty and stenting be performed before CAGB in patients with asymptomatic carotid stenosis?. Nature Reviews: Neurology. 2008;4:250-251. (2008) Abstract

Goldstein, LB; Amarenco, P; Lamonte, M; Gilbert, S; Messig, M; Callahan, A; Hennerici, M; Sillesen, H; Welch, KM; SPARCL Investigators. Relative effects of statin therapy on stroke and cardiovascular events in men and women: secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Study. Stroke. 2008;39:2444-2448. (2008) Abstract

Goldstein, LB; Amarenco, P; Szarek, M; Callahan, A; Hennerici, M; Sillesen, H; Zivin, JA; Welch, KM; SPARCL Investigators. Hemorrhagic stroke in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels study. Neurology. 2008;70:2364-2370. (2008) Abstract

Goldstein, LB; Rothwell, PM. Advances in prevention and health services delivery 2007. Stroke. 2008;39:258-260. (2008) Abstract

Sillesen, H; Amarenco, P; Hennerici, MG; Callahan, A; Goldstein, LB; Zivin, J; Messig, M; Welch, KM; Stroke Prevention by Aggressive Reduction in Cholesterol Levels Investigators. Atorvastatin reduces the risk of cardiovascular events in patients with carotid atherosclerosis: a secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. Stroke. 2008;39:3297-3302. (2008) Abstract

Amarenco, P; Goldstein, LB; Szarek, M; Sillesen, H; Rudolph, AE; Callahan, A; Hennerici, M; Simunovic, L; Zivin, JA; Welch, KM; SPARCL Investigators. Effects of intense low-density lipoprotein cholesterol reduction in patients with stroke or transient ischemic attack: the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. Stroke. 2007;38:3198-3204. (2007) Abstract

Fletcher, GF; Bufalino, V; Costa, F; Goldstein, LB; Jones, D; Smaha, L; Smith, SC; Stone, N. Efficacy of drug therapy in the secondary prevention of cardiovascular disease and stroke. American Journal of Cardiology. 2007;99:1E-35E. (2007) Abstract

Goldstein, LB. Acute ischemic stroke treatment in 2007. Circulation. 2007;116:1504-1514. (2007) Abstract

Goldstein, LB. Effect of constraint-induced movement therapy on upper extremity function 3 to 9 months after stroke: the EXCITE trial. Current Atherosclerosis Reports. 2007;9:259-260. (2007) Abstract

Goldstein, LB. Low LDL cholesterol, statins, and brain hemorrhage: should we worry?. Neurology. 2007;68:719-720. (2007) Abstract

Goldstein, LB. Magnetic resonance imaging profiles predict clinical response to early reperfusion: the DEFUSE study. Current Atherosclerosis Reports. 2007;9:258-259. (2007) Abstract

Goldstein, LB. Regulatory device approval for stroke: fair and balanced?. Stroke. 2007;38:1737-1738. (2007) Abstract

Goldstein, LB. Statins for stroke prevention. Current Atherosclerosis Reports. 2007;9:305-311. (2007) Abstract

Goldstein, LB. Stroke code chest radiographs are not useful. Cerebrovascular Diseases. 2007;24:460-462. (2007) Abstract

Goldstein, LB; Rothwell, PM. Primary prevention and health services delivery. Stroke. 2007;38:222-224. (2007) Abstract

Abou-Donia, MB; Khan, WA; Dechkovskaia, AM; Goldstein, LB; Bullman, SL; Abdel-Rahman, A. In utero exposure to nicotine and chlorpyrifos alone, and in combination produces persistent sensorimotor deficits and Purkinje neuron loss in the cerebellum of adult offspring rats. Archives of Toxicology. 2006;80:620-631. (2006) Abstract

Amarenco, P; Bogousslavsky, J; Callahan, A; Goldstein, LB; Hennerici, M; Rudolph, AE; Sillesen, H; Simunovic, L; Szarek, M; Welch, KM; Zivin, JA; Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Investigators. High-dose atorvastatin after stroke or transient ischemic attack. New England Journal of Medicine. 2006;355:549-559. (2006) Abstract

Bushnell, CD; Griffin, J; Newby, LK; Goldstein, LB; Mahaffey, KW; Graffagnino, CA; Harrington, RA; White, HD; Simes, RJ; Califf, RM; Topol, EJ; Easton, JD. Statin use and sex-specific stroke outcomes in patients with vascular disease. Stroke. 2006;37:1427-1431. (2006) Abstract

Bushnell, CD; Hurn, P; Colton, C; Miller, VM; del Zoppo, G; Elkind, MS; Stern, B; Herrington, D; Ford-Lynch, G; Gorelick, P; James, A; Brown, CM; Choi, E; Bray, P; Newby, LK; Goldstein, LB; Simpkins, J. Advancing the study of stroke in women: summary and recommendations for future research from an NINDS-Sponsored Multidisciplinary Working Group. Stroke. 2006;37:2387-2399. (2006) Abstract

Goldstein, LB. Improving the clinical diagnosis of stroke. Stroke. 2006;37:754-755. (2006) Abstract

Goldstein, LB. Is there a causal relationship between the amount of alcohol consumption and stroke risk?. Stroke. 2006;37:1-2. (2006) Abstract

Goldstein, LB. Neurotransmitters and motor activity: effects on functional recovery after brain injury. NeuroRx. 2006;3:451-457. (2006) Abstract

Goldstein, LB. Primum non nocere: antithombotics after intracerebral hemorrhage?. Neurology. 2006;66:162-163. (2006) Abstract

Goldstein, LB; Adams, R; Alberts, MJ; Appel, LJ; Brass, LM; Bushnell, CD; Culebras, A; DeGraba, TJ; Gorelick, PB; Guyton, JR; Hart, RG; Howard, G; Kelly-Hayes, M; Nixon, JV; Sacco, RL; American Heart Association, ; American Stroke Association Stroke Council. Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2006;113:e873-e923. (2006) Abstract

Goldstein, LB; Adams, R; Alberts, MJ; Appel, LJ; Brass, LM; Bushnell, CD; Culebras, A; Degraba, TJ; Gorelick, PB; Guyton, JR; Hart, RG; Howard, G; Kelly-Hayes, M; Nixon, JV; Sacco, RL; American Heart Association/American Stroke Association Stroke Council, ; Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group, ; Cardiovascular Nursing Council, ; Clinical Cardiology Council, ; Nutrition, Physical Activity, and Metabolism Council, ; Quality of Care and Outcomes Research Interdisciplinary Working Group, ; American Academy of Neurology. Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: the American Academy of Neurology affirms the value of this guideline. Stroke. 2006;37:1583-1633. (2006) Abstract

Goldstein, LB; Hankey, GJ. Advances in primary stroke prevention. Stroke. 2006;37:317-319. (2006) Abstract

Goldstein, LB; Saver, JL. Thrombolysis in stroke: a medicolegal quagmire. Stroke. 2006;37:2663. (2006) Abstract

Irwin, RS; Baumann, MH; Bolser, DC; Boulet, LP; Braman, SS; Brightling, CE; Brown, KK; Canning, BJ; Chang, AB; Dicpinigaitis, PV; Eccles, R; Glomb, WB; Goldstein, LB; Graham, LM; Hargreave, FE; Kvale, PA; Lewis, SZ; McCool, FD; McCrory, DC; Prakash, UB; Pratter, MR; Rosen, MJ; Schulman, E; Shannon, JJ; Smith Hammond, C; Tarlo, SM; American College of Chest Physicians (ACCP). Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest. 2006;129:1S-23S. (2006) Abstract

Kaplan, KL; Goldstein, LB. What does cerebral platelet activation mean in the setting of carotid stenosis?. Neurology. 2006;66:792-793. (2006) Abstract

Sacco, RL; Adams, R; Albers, G; Alberts, MJ; Benavente, O; Furie, K; Goldstein, LB; Gorelick, P; Halperin, J; Harbaugh, R; Johnston, SC; Katzan, I; Kelly-Hayes, M; Kenton, EJ; Marks, M; Schwamm, LH; Tomsick, T; American Heart Association, ; American Stroke Association Council on Stroke, ; Council on Cardiovascular Radiology and Intervention, ; American Academy of Neurology. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. Stroke. 2006;37:577-617. (2006) Abstract

Sacco, RL; Adams, R; Albers, G; Alberts, MJ; Benavente, O; Furie, K; Goldstein, LB; Gorelick, P; Halperin, J; Harbaugh, R; Johnston, SC; Katzan, I; Kelly-Hayes, M; Kenton, EJ; Marks, M; Schwamm, LH; Tomsick, T; American Heart Association/American Stroke Association Council on Stroke, ; Council on Cardiovascular Radiology and Intervention, ; American Academy of Neurology. Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline. Circulation. 2006;113:e409-e449. (2006) Abstract

Saver, JL; Goldstein, LB. The new standing guideline committee policy of the American Stroke Association Stroke Council. Stroke. 2006;37:753. (2006) Abstract

Smith Hammond, CA; Goldstein, LB. Cough and aspiration of food and liquids due to oral-pharyngeal dysphagia: ACCP evidence-based clinical practice guidelines. Chest. 2006;129:154S-168S. (2006) Abstract

Adams, H; Adams, R; Del Zoppo, G; Goldstein, LB; Stroke Council of the American Heart Association, ; American Stroke Association. Guidelines for the early management of patients with ischemic stroke: 2005 guidelines update a scientific statement from the Stroke Council of the American Heart Association/American Stroke Association. Stroke. 2005;36:916-923. (2005) Abstract

Bushnell, CD; Goldstein, LB. Neurologists' evaluation and treatment of hyperhomocysteinemia in stroke patients. Journal of Stroke and Cerebrovascular Diseases. 2005;14:101-106. (2005) Abstract

Camilo, O; Goldstein, LB. Lower stroke-related mortality in counties with stroke centers: North Carolina Stroke Facilities Survey. Neurology. 2005;64:762-763. (2005) Abstract

Camilo, O; Goldstein, LB. Non-atherosclerotic vascular disease in the young. Journal of Thrombosis and Thrombolysis. 2005;20:93-103. (2005) Abstract

Goldstein, LB; Amarenco, P. Prevention and health services delivery. Stroke. 2005;36:222-224. (2005) Abstract

Goldstein, LB; Simel, DL. Is this patient having a stroke?. JAMA: Journal of the American Medical Association. 2005;293:2391-2402. (2005) Abstract

Schwamm, LH; Pancioli, A; Acker, JE; Goldstein, LB; Zorowitz, RD; Shephard, TJ; Moyer, P; Gorman, M; Johnston, SC; Duncan, PW; Gorelick, P; Frank, J; Stranne, SK; Smith, R; Federspiel, W; Horton, KB; Magnis, E; Adams, RJ; American Stroke Association's Task Force on the Development of Stroke Systems. Recommendations for the establishment of stroke systems of care: recommendations from the American Stroke Association's Task Force on the Development of Stroke Systems. Circulation. 2005;111:1078-1091. (2005) Abstract

Schwamm, LH; Pancioli, A; Acker, JE; Goldstein, LB; Zorowitz, RD; Shephard, TJ; Moyer, P; Gorman, M; Johnston, SC; Duncan, PW; Gorelick, P; Frank, J; Stranne, SK; Smith, R; Federspiel, W; Horton, KB; Magnis, E; Adams, RJ; American Stroke Association's Task Force on the Development of Stroke Systems. Recommendations for the establishment of stroke systems of care: recommendations from the American Stroke Association's Task Force on the Development of Stroke Systems. Stroke. 2005;36:690-703. (2005) Abstract

Abdel-Rahman, A; Dechkovskaia, AM; Goldstein, LB; Bullman, SH; Khan, W; El-Masry, EM; Abou-Donia, MB. Neurological deficits induced by malathion, DEET, and permethrin, alone or in combination in adult rats. Journal of Toxicology and Environmental Health Part A. 2004;67:331-356. (2004) Abstract

Abou-Donia, MB; Dechkovskaia, AM; Goldstein, LB; Abdel-Rahman, A; Bullman, SL; Khan, WA. Co-exposure to pyridostigmine bromide, DEET, and/or permethrin causes sensorimotor deficit and alterations in brain acetylcholinesterase activity. Pharmacology, Biochemistry and Behavior. 2004;77:253-262. (2004) Abstract

Anderson, DC; Goldstein, LB. Aspirin: it's hard to beat. Neurology. 2004;62:1036-1037. (2004) Abstract

Bonow, RO; Zipes, DP; Anderson, JL; Cheitlin, MD; Goldstein, LB; Grant, AO; Faxon, D; Lima, JA; Robertson, RM. Task force 5: Expert testimony and opinions. Journal of the American College of Cardiology. 2004;44:1747-1749. (2004) Abstract

Bushnell, CD; Goldstein, LB. Risk of ischemic stroke with tamoxifen treatment for breast cancer: a meta-analysis. Neurology. 2004;63:1230-1233. (2004) Abstract

Bushnell, CD; Newby, LK; Goldstein, LB; Lin, F; Yaffe, K; Simon, JA. Statin use and stroke outcomes in the Heart and Estrogen-Progestin Replacement Study (HERS). Neurology. 2004;62:968-970. (2004) Abstract

Camilo, O; Goldstein, LB. Seizures and epilepsy after ischemic stroke. Stroke. 2004;35:1769-1775. (2004) Abstract

Goldstein, LB. Blood pressure management in patients with acute ischemic stroke. Hypertension. 2004;43:137-141. (2004) Abstract

Goldstein, LB. Neuroprotective therapy for acute ischaemic stroke: down, but not out. Lancet. 2004;363:414-415. (2004) Abstract

Goldstein, LB; Amarenco, P. Prevention and health services delivery. Stroke. 2004;35:401-403. (2004) Abstract

Goldstein, LB; Amarenco, P; Bogousslavsky, J; Callahan, AS; Hennerici, MG; Welch, KM; Zivin, J; Sillesen, H. Statins for secondary stroke prevention in patients without known coronary heart disease: the jury is still out. Cerebrovascular Diseases. 2004;18:1-2. (2004) Abstract

Goldstein, LB; Samsa, GP; Matchar, DB; Horner, RD. Charlson Index comorbidity adjustment for ischemic stroke outcome studies. Stroke. 2004;35:1941-1945. (2004) Abstract

Popp, RJ; Smith, SC; Adams, RJ; Antman, EM; Kavey, RE; DeMaria, AN; Ohman, EM; Pitt, B; Willerson, JT; Bellande, BJ; Fonarow, GC; Nishimura, RA; Shah, PM; Hirshfeld, JW; Messer, JV; Peterson, ED; Prystowsky, EN; Anderson, JL; Cheitlin, MD; Goldstein, LB; Grant, AO; Beller, GA; Hines, EF; Livingston, DW; McEntree, CW; American College of Cardiology Foundation, ; American Heart Association. ACCF/AHA consensus conference report on professionalism and ethics. Circulation. 2004;110:2506-2549. (2004) Abstract

Rothwell, PM; Goldstein, LB. Carotid endarterectomy for asymptomatic carotid stenosis: asymptomatic carotid surgery trial. Stroke. 2004;35:2425-2427. (2004) Abstract

Abou-Donia, MB; Abdel-Rahman, A; Goldstein, LB; Dechkovskaia, AM; Shah, DU; Bullman, SL; Khan, WA. Sensorimotor deficits and increased brain nicotinic acetylcholine receptors following exposure to chlorpyrifos and/or nicotine in rats. Archives of Toxicology. 2003;77:452-458. (2003) Abstract

Adams, HP; Adams, RJ; Brott, T; del Zoppo, GJ; Furlan, A; Goldstein, LB; Grubb, RL; Higashida, R; Kidwell, C; Kwiatkowski, TG; Marler, JR; Hademenos, GJ; Stroke Council of the American Stroke Association. Guidelines for the early management of patients with ischemic stroke: A scientific statement from the Stroke Council of the American Stroke Association. Stroke. 2003;34:1056-1083. (2003) Abstract

Anderson, DJ; Goldstein, LB; Wilkinson, WE; Corey, GR; Cabell, CH; Sanders, LL; Sexton, DJ. Stroke location, characterization, severity, and outcome in mitral vs aortic valve endocarditis. Neurology. 2003;61:1341-1346. (2003) Abstract

Bushnell, C; Goldstein, LB. Screening for hypercoagulable syndromes following stroke. Current Atherosclerosis Reports. 2003;5:291-298. (2003) Abstract

Camilo, O; Goldstein, LB. Statewide assessment of hospital-based stroke prevention and treatment services in North Carolina: changes over the last 5 years. Stroke. 2003;34:2945-2950. (2003) Abstract

Goldstein, LB. Amphetamines and related drugs in motor recovery after stroke. Physical Medicine and Rehabilitation Clinics of North America. 2003;14:S125-x. (2003) Abstract

Goldstein, LB. Editorial comment--Advertising strategies to increase the public knowledge of the warning signs of stroke. Stroke. 2003;34:1968-1969. (2003) Abstract

Goldstein, LB. Editorial comment--Prenatal influences on stroke mortality in England and Wales. Stroke. 2003;34:1602-1603. (2003) Abstract

Goldstein, LB. Extracranial carotid artery stenosis. Stroke. 2003;34:2767-2773. (2003) Abstract

Goldstein, LB. Model of recovery of locomotor ability after sensorimotor cortex injury in rats. Institute for Laboratory Animal Research (ILAR) Journal. 2003;44:125-129. (2003) Abstract

Goldstein, LB. Neuropharmacology of TBI-induced plasticity. Brain Injury. 2003;17:685-694. (2003) Abstract

Goldstein, LB. Pharmacotherapy in stroke rehabilitation. Advances in Neurology. 2003;92:447-450. (2003) Abstract

Goldstein, LB. Prevention and health services delivery. Stroke. 2003;34:367-369. (2003) Abstract

Goldstein, LB; Matchar, DB; Hoff-Lindquist, J; Samsa, GP; Horner, RD. VA Stroke Study: neurologist care is associated with increased testing but improved outcomes. Neurology. 2003;61:792-796. (2003) Abstract

Goldstein, LB; Matchar, DB; Hoff-Lindquist, J; Samsa, GP; Horner, RD. Veterans Administration Acute Stroke (VASt) Study: lack of race/ethnic-based differences in utilization of stroke-related procedures or services. Stroke. 2003;34:999-1004. (2003) Abstract

Marler, JR; Goldstein, LB. Medicine. Stroke--tPA and the clinic. Science. 2003;301:1677. (2003) Abstract

McGirt, MJ; Blessing, RP; Goldstein, LB. Transcranial Doppler monitoring and clinical decision-making after subarachnoid hemorrhage. Journal of Stroke and Cerebrovascular Diseases. 2003;12:88-92. (2003) Abstract

Pearson, TA; Bazzarre, TL; Daniels, SR; Fair, JM; Fortmann, SP; Franklin, BA; Goldstein, LB; Hong, Y; Mensah, GA; Sallis, JF; Smith, S; Stone, NJ; Taubert, KA; American Heart Association Expert Panel on Population and Prevention Science. American Heart Association guide for improving cardiovascular health at the community level: a statement for public health practitioners, healthcare providers, and health policy makers from the American Heart Association Expert Panel on Population and Prevention Science. Circulation. 2003;107:645-651. (2003) Abstract

Abou-Donia, MB; Dechkovskaia, AM; Goldstein, LB; Bullman, SL; Khan, WA. Sensorimotor deficit and cholinergic changes following coexposure with pyridostigmine bromide and sarin in rats. Toxicological Sciences. 2002;66:148-158. (2002) Abstract

Abou-Donia, MB; Dechkovskaia, AM; Goldstein, LB; Shah, DU; Bullman, SL; Khan, WA. Uranyl acetate-induced sensorimotor deficit and increased nitric oxide generation in the central nervous system in rats. Pharmacology, Biochemistry and Behavior. 2002;72:881-890. (2002) Abstract

Bushnell, CD; Goldstein, LB. Homocysteine testing in patients with acute ischemic stroke. Neurology. 2002;59:1541-1546. (2002) Abstract

Bushnell, CD; Goldstein, LB. Physician knowledge and practices in the evaluation of coagulopathies in stroke patients. Stroke. 2002;33:948-953. (2002) Abstract

Coull, BM; Williams, LS; Goldstein, LB; Meschia, JF; Heitzman, D; Chaturvedi, S; Johnston, KC; Starkman, S; Morgenstern, LB; Wilterdink, JL; Levine, SR; Saver, JL; American Academy of Neurology, ; American Stroke Association. Anticoagulants and antiplatelet agents in acute ischemic stroke: report of the Joint Stroke Guideline Development Committee of the American Academy of Neurology and the American Stroke Association (a division of the American Heart Association). Neurology. 2002;59:13-22. (2002) Abstract

Coull, BM; Williams, LS; Goldstein, LB; Meschia, JF; Heitzman, D; Chaturvedi, S; Johnston, KC; Starkman, S; Morgenstern, LB; Wilterdink, JL; Levine, SR; Saver, JL; Joint Stroke Guideline Development Committee of the American Academy of Neurology, ; American Stroke Association. Anticoagulants and antiplatelet agents in acute ischemic stroke: report of the Joint Stroke Guideline Development Committee of the American Academy of Neurology and the American Stroke Association (a division of the American Heart Association). Stroke. 2002;33:1934-1942. (2002) Abstract

Goldstein, LB; Albers, GW. Patient safety in trials of therapy for acute ischemic stroke. JAMA: Journal of the American Medical Association. 2002;287:987. (2002) Abstract

Goldstein, LB; Bullman, S. Differential effects of haloperidol and clozapine on motor recovery after sensorimotor cortex injury in rats. Neurorehabilitation and Neural Repair. 2002;16:321-325. (2002) Abstract

Goldstein, LB; Lyden, P; Mathias, SD; Colman, SS; Pasta, DJ; Albers, G; Atkinson, R; Kelley, G; Ng, K; Rylander, A. Telephone assessment of functioning and well-being following stroke: is it feasible?. Journal of Stroke and Cerebrovascular Diseases. 2002;11:80-87. (2002) Abstract

Johnston, DC; Eastwood, JD; Nguyen, T; Goldstein, LB. Contrast-enhanced magnetic resonance angiography of carotid arteries: utility in routine clinical practice. Stroke. 2002;33:2834-2838. (2002) Abstract

Johnston, DC; Goldstein, LB. Utility of noninvasive studies in the evaluation of patients with carotid artery disease. Current Neurology and Neuroscience Reports. 2002;2:25-30. (2002) Abstract

Pearson, TA; Blair, SN; Daniels, SR; Eckel, RH; Fair, JM; Fortmann, SP; Franklin, BA; Goldstein, LB; Greenland, P; Grundy, SM; Hong, Y; Miller, NH; Lauer, RM; Ockene, IS; Sacco, RL; Sallis, JF; Smith, SC; Stone, NJ; Taubert, KA. AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update: Consensus Panel Guide to Comprehensive Risk Reduction for Adult Patients Without Coronary or Other Atherosclerotic Vascular Diseases. American Heart Association Science Advisory and Coordinating Committee. Circulation. 2002;106:388-391. (2002) Abstract

Abou-Donia, MB; Goldstein, LB; Dechovskaia, A; Bullman, S; Jones, KH; Herrick, EA; Abdel-Rahman, AA; Khan, WA. Effects of daily dermal application of DEET and epermethrin, alone and in combination, on sensorimotor performance, blood-brain barrier, and blood-testis barrier in rats. Journal of Toxicology and Environmental Health Part A. 2001;62:523-541. (2001) Abstract

Abou-Donia, MB; Goldstein, LB; Jones, KH; Abdel-Rahman, AA; Damodaran, TV; Dechkovskaia, AM; Bullman, SL; Amir, BE; Khan, WA. Locomotor and sensorimotor performance deficit in rats following exposure to pyridostigmine bromide, DEET, and permethrin, alone and in combination. Toxicological Sciences. 2001;60:305-314. (2001) Abstract

Albers, GW; Goldstein, LB; Hall, D; Lesko, LM; Aptiganel Acute Stroke Investigators. Aptiganel hydrochloride in acute ischemic stroke: a randomized controlled trial. JAMA: Journal of the American Medical Association. 2001;286:2673-2682. (2001) Abstract

Bushnell, C; Siddiqi, Z; Morgenlander, JC; Goldstein, LB. Use of specialized coagulation testing in the evaluation of patients with acute ischemic stroke. Neurology. 2001;56:624-627. (2001) Abstract

Bushnell, CD; Datta, SK; Goldstein, LB. Cost implications of specialized coagulation testing for acute ischemic stroke. Journal of Stroke and Cerebrovascular Diseases. 2001;10:279-283. (2001) Abstract

Bushnell, CD; Johnston, DC; Goldstein, LB. Retrospective assessment of initial stroke severity: comparison of the NIH Stroke Scale and the Canadian Neurological Scale. Stroke. 2001;32:656-660. (2001) Abstract

Bushnell, CD; Samsa, GP; Goldstein, LB. Hormone replacement therapy and ischemic stroke severity in women: a case-control study. Neurology. 2001;56:1304-1307. (2001) Abstract

Bushnell, CD; Siddiqi, Z; Goldstein, LB. Improving patient selection for coagulopathy testing in the setting of acute ischemic stroke. Neurology. 2001;57:1333-1335. (2001) Abstract

Goldstein, LB. Medical therapy for acute ischemic stroke. Current Atherosclerosis Reports. 2001;3:299-306. (2001) Abstract

Goldstein, LB; Adams, R; Becker, K; Furberg, CD; Gorelick, PB; Hademenos, G; Hill, M; Howard, G; Howard, VJ; Jacobs, B; Levine, SR; Mosca, L; Sacco, RL; Sherman, DG; Wolf, PA; del Zoppo, GJ. Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association. Circulation. 2001;103:163-182. (2001) Abstract

Goldstein, LB; Adams, R; Becker, K; Furberg, CD; Gorelick, PB; Hademenos, G; Hill, M; Howard, G; Howard, VJ; Jacobs, B; Levine, SR; Mosca, L; Sacco, RL; Sherman, DG; Wolf, PA; del Zoppo, GJ. Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association. Stroke. 2001;32:280-299. (2001) Abstract

Goldstein, LB; Edwards, MG; Wood, DP. Delay between stroke onset and emergency department evaluation. Neuroepidemiology. 2001;20:196-200. (2001) Abstract

Goldstein, LB; Jones, MR; Matchar, DB; Edwards, LJ; Hoff, J; Chilukuri, V; Armstrong, SB; Horner, RD. Improving the reliability of stroke subgroup classification using the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria. Stroke. 2001;32:1091-1098. (2001) Abstract

Johnston, DC; Chapman, KM; Goldstein, LB. Low rate of complications of cerebral angiography in routine clinical practice. Neurology. 2001;57:2012-2014. (2001) Abstract

Johnston, DC; Goldstein, LB. Clinical carotid endarterectomy decision making: noninvasive vascular imaging versus angiography. Neurology. 2001;56:1009-1015. (2001) Abstract

Smith Hammond, CA; Goldstein, LB; Zajac, DJ; Gray, L; Davenport, PW; Bolser, DC. Assessment of aspiration risk in stroke patients with quantification of voluntary cough. Neurology. 2001;56:502-506. (2001) Abstract

Bushnell, CD; Goldstein, LB. Diagnostic testing for coagulopathies in patients with ischemic stroke. Stroke. 2000;31:3067-3078. (2000) Abstract

Goldstein, LB. Effects of amphetamines and small related molecules on recovery after stroke in animals and man. Neuropharmacology. 2000;39:852-859. (2000) Abstract

Goldstein, LB. Novel risk factors for stroke: homocysteine, inflammation, and infection. Current Atherosclerosis Reports. 2000;2:110-114. (2000) Abstract

Goldstein, LB. Rehabilitation and Recovery After Stroke. Current Treatment Options in Neurology. 2000;2:319-328. (2000) Abstract

Goldstein, LB. Should antihypertensive therapies be given to patients with acute ischemic stroke?. Drug Safety. 2000;22:13-18. (2000) Abstract

Goldstein, LB. The use of surface electromyography in objective measurement of the muscle function in facial pain/temporomandibular dysfunction patients. The Functional orthodontist. 2000;17:26-29. (2000) Abstract

Goldstein, LB; Bian, J; Samsa, GP; Bonito, AJ; Lux, LJ; Matchar, DB. New transient ischemic attack and stroke: outpatient management by primary care physicians. Archives of Internal Medicine. 2000;160:2941-2946. (2000) Abstract

Goldstein, LB; Hey, LA; Laney, R. North Carolina stroke prevention and treatment facilities survey. Statewide availability of programs and services. Stroke. 2000;31:66-70. (2000) Abstract

Goldstein, LB; Howard, G. Stroke in patients with asymptomatic internal-carotid-artery stenosis. New England Journal of Medicine. 2000;343:1420. (2000) Abstract

Goldstein, LB; Vitek, MP; Dawson, H; Bullman, S. Expression of the apolipoprotein E gene does not affect motor recovery after sensorimotor cortex injury in the mouse. Neuroscience. 2000;99:705-710. (2000) Abstract

Samsa, GP; Matchar, DB; Goldstein, LB; Bonito, AJ; Lux, LJ; Witter, DM; Bian, J. Quality of anticoagulation management among patients with atrial fibrillation: results of a review of medical records from 2 communities. Archives of Internal Medicine. 2000;160:967-973. (2000) Abstract

Goldstein, LB. Amphetamine-facilitated poststroke recovery. Stroke. 1999;30:696-698. (1999) Abstract

Goldstein, LB. Carotid endarterectomy for stroke prevention in older people. Clinics in Geriatric Medicine. 1999;15:685-700. (1999) Abstract

Goldstein, LB. Carotid endarterectomy. New England Journal of Medicine. 1999;340:1209. (1999) Abstract

Goldstein, LB. Evidence-based medicine and stroke. Neuroepidemiology. 1999;18:120-124. (1999) Abstract

Goldstein, LB. Pharmacological approach to functional reorganization: the role of norepinephrine. Revue Neurologique. 1999;155:731-736. (1999) Abstract

Goldstein, LB; Brott, TG; Kothari, RU; Smith, WS. Clinical stroke trials: guarding against bias. Stroke. 1999;30:1165-1166. (1999) Abstract

Goldstein, LB; Bullman, S. Age but not sex affects motor recovery after unilateral sensorimotor cortex suction-ablation in the rat. Restorative Neurology and Neuroscience. 1999;15:39-43. (1999) Abstract

Goldstein, LB; Chu, CT; Gray, L; Hulette, CM. Angiographically defined primary angiitis of the CNS: is it really benign?. Neurology. 1999;52:1302. (1999) Abstract

Goldstein, LB; Gradison, M. Stroke-related knowledge among patients with access to medical care in the stroke belt. Journal of Stroke and Cerebrovascular Diseases. 1999;8:349-352. (1999) Abstract

Wolf, PA; Clagett, GP; Easton, JD; Goldstein, LB; Gorelick, PB; Kelly-Hayes, M; Sacco, RL; Whisnant, JP. Preventing ischemic stroke in patients with prior stroke and transient ischemic attack : a statement for healthcare professionals from the Stroke Council of the American Heart Association. Stroke. 1999;30:1991-1994. (1999) Abstract

Chu, CT; Gray, L; Goldstein, LB; Hulette, CM. Diagnosis of intracranial vasculitis: a multi-disciplinary approach. Journal of Neuropathology and Experimental Neurology. 1998;57:30-38. (1998) Abstract

Goldstein, LB. Accuracy of ICD-9-CM coding for the identification of patients with acute ischemic stroke: effect of modifier codes. Stroke. 1998;29:1602-1604. (1998) Abstract

Goldstein, LB. Potential effects of common drugs on stroke recovery. Archives of Neurology. 1998;55:454-456. (1998) Abstract

Goldstein, LB; Cohen, SJ; Matchar, DB; Bonito, AJ; Samsa, GP. Physician-reported readiness to change stroke prevention practices. Journal of Stroke and Cerebrovascular Diseases. 1998;7:358-363. (1998) Abstract

Goldstein, LB; Hey, LA; Laney, R. North Carolina stroke prevention and treatment facilities survey: rtPA therapy for acute stroke. Stroke. 1998;29:2069-2072. (1998) Abstract

Goldstein, LB; Samsa, GP; Matchar, DB; Oddone, EZ. Multicenter review of preoperative risk factors for endarterectomy for asymptomatic carotid artery stenosis. Stroke. 1998;29:750-753. (1998) Abstract

Whetten-Goldstein, K; Sloan, FA; Goldstein, LB; Kulas, ED. A comprehensive assessment of the cost of multiple sclerosis in the United States. Multiple Sclerosis. 1998;4:419-425. (1998) Abstract

Duncan, PW; Samsa, GP; Weinberger, M; Goldstein, LB; Bonito, A; Witter, DM; Enarson, C; Matchar, D. Health status of individuals with mild stroke. Stroke. 1997;28:740-745. (1997) Abstract

Goldstein, LB. Effects of bilateral and unilateral locus coeruleus lesions on beam-walking recovery after subsequent unilateral sensorimotor cortex suction-ablation in the rat. Restorative Neurology and Neuroscience. 1997;11:55-63. (1997) Abstract

Goldstein, LB. Influence of common drugs and related factors on stroke outcome. Current Opinion in Neurology. 1997;10:52-57. (1997) Abstract

Goldstein, LB; Bullman, S. Effects of dorsal noradrenergic bundle lesions on recovery after sensorimotor cortex injury. Pharmacology, Biochemistry and Behavior. 1997;58:1151-1157. (1997) Abstract

Goldstein, LB; Chilukuri, V. Retrospective assessment of initial stroke severity with the Canadian Neurological Scale. Stroke. 1997;28:1181-1184. (1997) Abstract

Goldstein, LB; Farmer, A; Matchar, DB. Primary care physician-reported secondary and tertiary stroke prevention practices. A comparison between the United States and the United Kingdom. Stroke. 1997;28:746-751. (1997) Abstract

Goldstein, LB; Last, FC; Salerno, VM. Prevalence of hyperactive digastric muscles during swallowing as measured by electromyography in patients with myofascial pain dysfunction syndrome. The Functional orthodontist. 1997;14:18-24. (1997) Abstract

Goldstein, LB; Moore, WS; Robertson, JT; Chaturvedi, S. Complication rates for carotid endarterectomy. A call to action. Stroke. 1997;28:889-890. (1997) Abstract

Goldstein, LB; Samsa, GP. Reliability of the National Institutes of Health Stroke Scale. Extension to non-neurologists in the context of a clinical trial. Stroke. 1997;28:307-310. (1997) Abstract

Matchar, DB; Oddone, EZ; McCrory, DC; Goldstein, LB; Landsman, PB; Samsa, G; Brook, RH; Kamberg, C; Hilborne, L; Leape, L; Horner, R. Influence of projected complication rates on estimated appropriate use rates for carotid endarterectomy. Appropriateness Project Investigators. Academic Medical Center Consortium. Health Services Research. 1997;32:325-342. (1997) Abstract

Sacco, RL; Benjamin, EJ; Broderick, JP; Dyken, M; Easton, JD; Feinberg, WM; Goldstein, LB; Gorelick, PB; Howard, G; Kittner, SJ; Manolio, TA; Whisnant, JP; Wolf, PA. American Heart Association Prevention Conference. IV. Prevention and Rehabilitation of Stroke. Risk factors. Stroke. 1997;28:1507-1517. (1997) Abstract

Samsa, GP; Cohen, SJ; Goldstein, LB; Bonito, AJ; Duncan, PW; Enarson, C; DeFriese, GH; Horner, RD; Matchar, DB. Knowledge of risk among patients at increased risk for stroke. Stroke. 1997;28:916-921. (1997) Abstract

Goldstein, LB. Sacral pseudoradiculopathy due to centrum semiovale stroke. Journal of Stroke and Cerebrovascular Diseases. 1996;6:41-44. (1996) Abstract

Goldstein, LB; Bonito, AJ; Matchar, DB; Duncan, PW; Samsa, GP. US National Survey of Physician Practices for the Secondary and Tertiary Prevention of Ischemic Stroke. Carotid endarterectomy. Stroke. 1996;27:801-806. (1996) Abstract

Goldstein, LB; Bonito, AJ; Matchar, DB; Duncan, PW; Samsa, GP. US National Survey of Physician Practices for the Secondary and Tertiary Prevention of Ischemic Stroke. Medical therapy in patients with carotid artery stenosis. Stroke. 1996;27:1473-1478. (1996) Abstract

Alberts, MJ; Goldstein, LB; Smith, T. Guidelines on the use of thrombolytic agents in stroke. JAMA: Journal of the American Medical Association. 1995;274:218. (1995) Abstract

Goldstein, LB. Common drugs may influence motor recovery after stroke. The Sygen In Acute Stroke Study Investigators. Neurology. 1995;45:865-871. (1995) Abstract

Goldstein, LB. Prescribing of potentially harmful drugs to patients admitted to hospital after head injury. Journal of Neurology, Neurosurgery and Psychiatry. 1995;58:753-755. (1995) Abstract

Goldstein, LB. Right vs. left sensorimotor cortex suction-ablation in the rat: no difference in beam-walking recovery. Brain Research. 1995;674:167-170. (1995) Abstract

Goldstein, LB; Bonito, AJ; Matchar, DB; Duncan, PW; DeFriese, GH; Oddone, EZ; Paul, JE; Akin, DR; Samsa, GP. US national survey of physician practices for the secondary and tertiary prevention of ischemic stroke. Design, service availability, and common practices. Stroke. 1995;26:1607-1615. (1995) Abstract

Goldstein, LB; Gray, L; Hulette, CM. Stroke due to recurrent ipsilateral carotid artery dissection in a young adult. Stroke. 1995;26:480-483. (1995) Abstract

Goldstein, LB; Hasselblad, V; Matchar, DB; McCrory, DC. Comparison and meta-analysis of randomized trials of endarterectomy for symptomatic carotid artery stenosis. Neurology. 1995;45:1965-1970. (1995) Abstract

Grotta, J; Clark, W; Coull, B; Pettigrew, LC; Mackay, B; Goldstein, LB; Meissner, I; Murphy, D; LaRue, L. Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke. Results of a phase IIa randomized trial. Stroke. 1995;26:602-605. (1995) Abstract

Duncan, PW; Goldstein, LB; Horner, RD; Landsman, PB; Samsa, GP; Matchar, DB. Similar motor recovery of upper and lower extremities after stroke. Stroke. 1994;25:1181-1188. (1994) Abstract

Goldstein, LB. Clinical preventive practice. Health Reports. 1994;6:139-141. (1994) Abstract

Goldstein, LB. Sample size calculations for clinical trials using the NIH Stroke Scale. Stroke. 1994;25:1700-1701. (1994) Abstract

Goldstein, LB; Matchar, DB. The Stroke P.O.R.T.: secondary and tertiary prevention of ischemic stroke. Stroke Prevention Patient Outcomes Research Team. Health Reports. 1994;6:154-159. (1994) Abstract

Goldstein, LB; Matchar, DB. The rational clinical examination. Clinical assessment of stroke. JAMA: Journal of the American Medical Association. 1994;271:1114-1120. (1994) Abstract

Goldstein, LB; McCrory, DC; Landsman, PB; Samsa, GP; Ancukiewicz, M; Oddone, EZ; Matchar, DB. Multicenter review of preoperative risk factors for carotid endarterectomy in patients with ipsilateral symptoms. Stroke. 1994;25:1116-1121. (1994) Abstract

Goldstein, LB. Basic and clinical studies of pharmacologic effects on recovery from brain injury. Journal of Neural Transplantation and Plasticity. 1993;4:175-192. (1993) Abstract

Goldstein, LB. Rapid reliable measurement of lesion parameters for studies of motor recovery after sensorimotor cortex injury in the rat. Journal of Neuroscience Methods. 1993;48:35-42. (1993) Abstract

Goldstein, LB; Macmillan, V. Acute unilateral sensorimotor cortex injury in the rat blocks d-amphetamine induced norepinephrine release in cerebellum. Restorative Neurology and Neuroscience. 1993;5:371-376. (1993) Abstract

McCrory, DC; Goldstein, LB; Samsa, GP; Oddone, EZ; Landsman, PB; Moore, WS; Matchar, DB. Predicting complications of carotid endarterectomy. Stroke. 1993;24:1285-1291. (1993) Abstract

Duncan, PW; Goldstein, LB; Matchar, D; Divine, GW; Feussner, J. Measurement of motor recovery after stroke. Outcome assessment and sample size requirements. Stroke. 1992;23:1084-1089. (1992) Abstract

Goldstein, LB; Coviello, A. Post-lesion administration of the NMDA receptor antagonist MK-801 does not impair motor recovery after unilateral sensorimotor cortex injury in the rat. Brain Research. 1992;580:129-136. (1992) Abstract

Goldstein, LB; Perry, A. Early recurrent ischemic stroke. A case-control study. Stroke. 1992;23:1010-1013. (1992) Abstract

Goldstein, LB; Coviello, A; Miller, GD; Davis, JN. Norepinephrine depletion impairs motor recovery following sensorimotor cortex injury in the rat. Restorative Neurology and Neuroscience. 1991;3:41-47. (1991) Abstract

Morgenlander, JC; Goldstein, LB. Recurrent transient ischemic attacks and stroke in association with an internal carotid artery web. Stroke. 1991;22:94-98. (1991) Abstract

Goldstein, LB. Pharmacology of recovery after stroke. Stroke. 1990;21:III139-III142. (1990) Abstract

Goldstein, LB; Davis, JN. Beam-walking in rats: studies towards developing an animal model of functional recovery after brain injury. Journal of Neuroscience Methods. 1990;31:101-107. (1990) Abstract

Goldstein, LB; Davis, JN. Clonidine impairs recovery of beam-walking after a sensorimotor cortex lesion in the rat. Brain Research. 1990;508:305-309. (1990) Abstract

Goldstein, LB; Davis, JN. Influence of lesion size and location on amphetamine-facilitated recovery of beam-walking in rats. Behavioral Neuroscience. 1990;104:320-327. (1990) Abstract

Goldstein, LB; Davis, JN. Post-lesion practice and amphetamine-facilitated recovery of beam-walking in the rat. Restorative Neurology and Neuroscience. 1990;1:311-314. (1990) Abstract

Goldstein, LB; Davis, JN. Restorative neurology. Drugs and recovery following stroke. Stroke. 1990;21:1636-1640. (1990) Abstract

Massey, EW; Biller, J; Davis, JN; Adams, HP; Marler, JR; Goldstein, LB; Alberts, M; Bruno, A. Large-dose infusions of heparinoid ORG 10172 in ischemic stroke. Stroke. 1990;21:1289-1292. (1990) Abstract

Biller, J; Massey, EW; Marler, JR; Adams, HP; Davis, JN; Bruno, A; Henriksen, RA; Linhardt, RJ; Goldstein, LB; Alberts, M. A dose escalation study of ORG 10172 (low molecular weight heparinoid) in stroke. Neurology. 1989;39:262-265. (1989) Abstract

Goldstein, LB; Bertels, C; Davis, JN. Interrater reliability of the NIH stroke scale. Archives of Neurology. 1989;46:660-662. (1989) Abstract

Goldstein, LB; Davis, JN. Physician prescribing patterns following hospital admission for ischemic cerebrovascular disease. Neurology. 1988;38:1806-1809. (1988) Abstract

Epstein, HT; Goldstein, LB. Construction of low-variability litters of preweaning mice. Developmental Psychobiology. 1977;10:575-577. (1977) Abstract