Department / Division:
Medicine / Cellular Therapy

Address:
DUMC 3961
Durham, NC 27710

Appointment Telephone:
919-668-1011

Office Telephone:
919-668-4383

Fax Telephone:
919-668-1091

• MD, Indiana University School of Medicine, 1971

• Internal Medicine, University of Washington School of Medicine, 1971-1973, 1975-1976
• Oncology, American Cancer Society, University of Washington School of Medicine, 1976-1978

• Medical Oncology, Fred Hutchinson Cancer Research Center (Washington), 1978-1979

Clinical Interests:
Late effects of high-dose chemotherapy and stem-cell transplantation for hematologic malignancies, sickle cell and autoimmune disease

Research Interests:


Late effects of cancer treatment and stem cell transplantation
Chronic graft-versus-host disease
Transplantation for sickle cell and autoimmune diseases
Knowledge engineering in cancer medicine

Early on, Dr. Sullivan and the team at Fred Hutchinson Cancer Research Center developed a systematic investigative approach for the diagnosis and treatment of chronic graft-versus-host disease, the major cause of late morbidity and non-relapse mortality following allogeneic stem cell transplantation (SCT).  As a result of this work, it became clear that blood and marrow transplant recipients require systematic long-term follow-up to evaluate and treat late complications of high-dose chemoradiotherapy and SCT.  The program grew into a large multidisciplinary team, resulting in improvement in patient outcome and quality of life.  Through the late events project, he also contributed to outcomes research, computer decision support systems, and knowledge engineering for follow-up care (Figure 1).  With quality of life as a focus, research pursued the application of SCT to diseases with high morbidity but little immediate mortality.  For young patients with advanced, symptomatic sickle cell disease, myeloablative conditioning and SCT from an HLA-identical sibling has led to an 84% long-term survival free of sickle cell disease (Figure 2).  For individuals with autoimmune diseases such as multiple sclerosis, scleroderma, systemic lupus erythematosus and juvenile rheumatoid arthritis, current therapy is often incomplete and significant morbidity from the disease or its treatment is observed.  Recent preclinical and clinical data suggest that high-dose immunosupression and SCT can halt the progression and, in some settings, reverse the course of autoimmune diseases.  Since his arrival at Duke University in January 1999, over 30 centers nationwide are participating in Duke-led phase II and III trials to test the toxicity, efficacy, and quality of life following autologous and allogeneic stem cell transplantation for autoimmune diseases.  These trials will also serve as platforms to study the immune repertoire and mechanistic pathways before and after SCT to gain greater insight into the basic mechanisms of autoimmunity.  A national repository of tissue and cell specimens is also part of these NIH-supported trials to further promote scientific study from these unique patients.

Representative Publications:
Stevens AM, Sullivan KM, Nelson JL. Polymyositis as a manifestation of chronic graft-versus-host disease. Rheumatology (Oxford). 2003 Jan;42(1):34-9. (2003) Abstract

Sullivan KM. Bone marrow transplantation for non-malignant disease. Int J Hematol. 2002 Aug;76 Suppl 1:169-70. (2002) Abstract

McSweeney PA, Nash RA, Sullivan KM, Storek J, Crofford LJ, Dansey R, Mayes MD, McDonagh KT, Nelson JL, Gooley TA, Holmberg LA, Chen CS, Wener MH, Ryan K, Sunderhaus J, Russell K, Rambharose J, Storb R, Furst DE. High-dose immunosuppressive therapy for severe systemic sclerosis: initial outcomes. Blood. 2002 Sep 1;100(5):1602-10. (2002) Abstract

Goerner M, Gooley T, Flowers ME, Sullivan KM, Kiem HP, Sanders JE, Martin PJ, Storb R. Morbidity and mortality of chronic GVHD after hematopoietic stem cell transplantation from HLA-identical siblings for patients with aplastic or refractory anemias. Biol Blood Marrow Transplant. 2002;8(1):47-56. (2002) Abstract

Walters MC, Patience M, Leisenring W, Rogers ZR, Aquino VM, Buchanan GR, Roberts IA, Yeager AM, Hsu L, Adamkiewicz T, Kurtzberg J, Vichinsky E, Storer B, Storb R, Sullivan KM, . Stable mixed hematopoietic chimerism after bone marrow transplantation for sickle cell anemia. Biol Blood Marrow Transplant. 2001;7(12):665-73. (2001) Abstract

Sullivan KM, Dykewicz CA, Longworth DL, Boeckh M, Baden LR, Rubin RH, Sepkowitz KA, , , . Preventing opportunistic infections after hematopoietic stem cell transplantation: the Centers for Disease Control and Prevention, Infectious Diseases Society of America, and American Society for Blood and Marrow Transplantation Practice Guidelines and beyond. Hematology (Am Soc Hematol Educ Program). 2001;:392-421. (2001) Abstract

Storek J, Joseph A, Espino G, Dawson MA, Douek DC, Sullivan KM, Flowers ME, Martin P, Mathioudakis G, Nash RA, Storb R, Appelbaum FR, Maloney DG. Immunity of patients surviving 20 to 30 years after allogeneic or syngeneic bone marrow transplantation. Blood. 2001 Dec 15;98(13):3505-12. (2001) Abstract

Stern JM, Sullivan KM, Ott SM, Seidel K, Fink JC, Longton G, Sherrard DJ. Bone density loss after allogeneic hematopoietic stem cell transplantation: a prospective study. Biol Blood Marrow Transplant. 2001;7(5):257-64. (2001) Abstract

Socié G, Clift RA, Blaise D, Devergie A, Ringden O, Martin PJ, Remberger M, Deeg HJ, Ruutu T, Michallet M, Sullivan KM, Chevret S. Busulfan plus cyclophosphamide compared with total-body irradiation plus cyclophosphamide before marrow transplantation for myeloid leukemia: long-term follow-up of 4 randomized studies. Blood. 2001 Dec 15;98(13):3569-74. (2001) Abstract

Bruno B, Gooley T, Sullivan KM, Davis C, Bensinger WI, Storb R, Nash RA. Secondary failure of platelet recovery after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2001;7(3):154-62. (2001) Abstract

Walters MC, Storb R, Patience M, Leisenring W, Taylor T, Sanders JE, Buchanan GE, Rogers ZR, Dinndorf P, Davies SC, Roberts IA, Dickerhoff R, Yeager AM, Hsu L, Kurtzberg J, Ohene-Frempong K, Bunin N, Bernaudin F, Wong WY, Scott JP, Margolis D, Vichinsky E, Wall DA, Wayne AS, Pegelow C, Redding-Lallinger R, Wiley J, Klemperer M, Mentzer WC, Smith FO, Sullivan KM. Impact of bone marrow transplantation for symptomatic sickle cell disease: an interim report. Multicenter investigation of bone marrow transplantation for sickle cell disease. Blood. 2000 Mar 15;95(6):1918-24. (2000) Abstract

Sullivan KM, Parkman R, Walters MC. Bone Marrow Transplantation for Non-Malignant Disease. Hematology (Am Soc Hematol Educ Program). 2000;():319-338. (2000) Abstract

Stern JM, Bruemmer B, Moinpour CM, Sullivan KM, Lenssen P, Aker SN. Impact of a randomized, controlled trial of liberal vs conservative hospital discharge criteria on energy, protein, and fluid intake in patients who received marrow transplants. J Am Diet Assoc. 2000 Sep;100(9):1015-22. (2000) Abstract

Socié G, Curtis RE, Deeg HJ, Sobocinski KA, Filipovich AH, Travis LB, Sullivan KM, Rowlings PA, Kingma DW, Banks PM, Travis WD, Witherspoon RP, Sanders J, Jaffe ES, Horowitz MM. New malignant diseases after allogeneic marrow transplantation for childhood acute leukemia. J Clin Oncol. 2000 Jan;18(2):348-57. (2000) Abstract

Furlong, T., Storb, R, Anasetti, C., Appelbaum, F.R., Deeg, H.J., Doney, K., Martin, P., Sullivan, K., Witherspoon, R., Nash, R.A.. Clinical outcome after conversion to FK 506 (tacrolimus) therapy for acute graft-versus-host disease resistant to cyclosporine or for cyclosporine-associated toxicities. Bone Marrow Transplantation. 9: 985-91, 2000 (2000)

Dykewicz, C.A., Kaplan, J.E., Jaffe, H.W., Spira, T.J., Jarvis, W.R., Edlin, B.R., Chen R.T., Hibbs, B., Bowden, R.A., Sullivan, K.M., Emanuel, D., Longsworth, D.L., Rowlings, P.A., Rubin, R.H., Sepkowitz, K.A., Wingard, J.R.. Guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients: Recommendations of CDC, the Infectious Diseases Society of America, and the American Society of Blood and Marrow Transplantation.  Biol Blood Marrow Transplant. 6:659-34, 2000 (2000)

Carnevale-Schianca, F., Martin, P., Sullivan, K.M., Flowers, M., Gooley, T., Anasetti, C., Deeg, J., Furlong, T., McSweeney, P., Storb, R., Nash, R.. Changing cyclosporine to tacrolimus as salvage therapy for chronic graft-versus-host disease.  Biol Blood Marrow Transplant. 6:613-20, 2000 (2000)

Bush NE, Donaldson GW, Haberman MH, Dacanay R, Sullivan KM. Conditional and unconditional estimation of multidimensional quality of life after hematopoietic stem cell transplantation: a longitudinal follow-up of 415 patients. Biol Blood Marrow Transplant. 2000;6(5A):576-91. (2000) Abstract

Strasser SI, Sullivan KM, Myerson D, Spurgeon CL, Storer B, Schoch HG, Murakami CS, McDonald GB. Cirrhosis of the liver in long-term marrow transplant survivors. Blood. 1999 May 15;93(10):3259-66. (1999) Abstract

Feinstein LC, Seidel K, Jocum J, Bowden RA, Anasetti C, Deeg HJ, Flowers ME, Kansu E, Martin PJ, Nash RA, Storek J, Etzioni R, Applebaum FR, Hansen JA, Storb R, Sullivan KM. Reduced dose intravenous immunoglobulin does not decrease transplant-related complications in adults given related donor marrow allografts. Biol Blood Marrow Transplant. 1999;5(6):369-78. (1999) Abstract

Sullivan KM, Anasetti C, Horowitz M, Rowlings PA, Petersdorf EW, Martin PJ, Clift RA, Walters MC, Gooley T, Sierra J, Anderson JE, Bjerke J, Siadak M, Flowers ME, Nash RA, Sanders JE, Appelbaum FR, Storb R, Hansen JA. Unrelated and HLA-nonidentical related donor marrow transplantation for thalassemia and leukemia. A combined report from the Seattle Marrow Transplant Team and the International Bone Marrow Transplant Registry. Ann N Y Acad Sci. 1998 Jun 30;850:312-24. (1998) Abstract

Storb R, Yu C, Deeg HJ, Georges G, Kiem HP, Mcsweeney PA, Nash RA, Sandmaier BM, Sullivan KM, Wagner JL, Walters MC. Current and future preparative regimens for bone marrow transplantation in thalassemia. Ann N Y Acad Sci. 1998 Jun 30;850:276-87. (1998) Abstract

Morton AJ, Gooley T, Hansen JA, Appelbaum FR, Bruemmer B, Bjerke JW, Clift R, Martin PJ, Petersdorf EW, Sanders JE, Storb R, Sullivan KM, Woolfrey A, Anasetti C. Association between pretransplant interferon-alpha and outcome after unrelated donor marrow transplantation for chronic myelogenous leukemia in chronic phase. Blood. 1998 Jul 15;92(2):394-401. (1998) Abstract

Lopez-Cubero SO, Sullivan KM, McDonald GB. Course of Crohn's disease after allogeneic marrow transplantation. Gastroenterology. 1998 Mar;114(3):433-40. (1998) Abstract

Hansen JA, Gooley TA, Martin PJ, Appelbaum F, Chauncey TR, Clift RA, Petersdorf EW, Radich J, Sanders JE, Storb RF, Sullivan KM, Anasetti C. Bone marrow transplants from unrelated donors for patients with chronic myeloid leukemia. N Engl J Med. 1998 Apr 2;338(14):962-8. (1998) Abstract

Fink JC, Leisenring WM, Sullivan KM, Sherrard DJ, Weiss NS. Avascular necrosis following bone marrow transplantation: a case-control study. Bone. 1998 Jan;22(1):67-71. (1998) Abstract

Deeg HJ, Seidel K, Sullivan KM. Body weight and outcome of hematopoietic stem cell transplantation. Am J Med. 1998 Jun;104(6):607-8. (1998) Abstract

Deeg HJ, Leisenring W, Storb R, Nims J, Flowers ME, Witherspoon RP, Sanders J, Sullivan KM. Long-term outcome after marrow transplantation for severe aplastic anemia. Blood. 1998 May 15;91(10):3637-45. (1998) Abstract

Clift RA, Buckner CD, Appelbaum FR, Sullivan KM, Storb R, Thomas ED. Long-term follow-Up of a randomized trial of two irradiation regimens for patients receiving allogeneic marrow transplants during first remission of acute myeloid leukemia. Blood. 1998 Aug 15;92(4):1455-6. (1998) Abstract

Bichindaritz I, Siadak MF, Jocom J, Moinpour C, Kansu E, Donaldson G, Bush N, Chapko M, Bradshaw JM, Sullivan KM. CARE-PARTNER: a computerized knowledge-support system for stem-cell post-transplant long-term follow-up on the World-Wide-Web. Proc AMIA Symp. 1998;:386-90. (1998) Abstract

Walters MC, Patience M, Leisenring W, Rogers ZR, Dinndorf P, Davies SC, Roberts IA, Yeager A, Kurtzberg J, Bunin N, Scott JP, Wall DA, Wayne AS, Wiley J, Darbyshire PJ, Mentzer WC, Smith FO, Sullivan KM. Collaborative multicenter investigation of marrow transplantation for sickle cell disease: current results and future directions. Biol Blood Marrow Transplant. 1997 Dec;3(6):310-5. (1997) Abstract

Sullivan KM. Longterm followup and quality of life after hematopoietic stem cell transplantation. J Rheumatol Suppl. 1997 May;48:46-52. (1997) Abstract

Sullivan KM, Furst DE. The evolving role of blood and marrow transplantation for the treatment of autoimmune diseases. J Rheumatol Suppl. 1997 May;48:1-4. (1997) Abstract

Storek J, Gooley T, Witherspoon RP, Sullivan KM, Storb R. Infectious morbidity in long-term survivors of allogeneic marrow transplantation is associated with low CD4 T cell counts. Am J Hematol. 1997 Feb;54(2):131-8. (1997) Abstract

Storek J, Gooley T, Siadak M, Bensinger WI, Maloney DG, Chauncey TR, Flowers M, Sullivan KM, Witherspoon RP, Rowley SD, Hansen JA, Storb R, Appelbaum FR. Allogeneic peripheral blood stem cell transplantation may be associated with a high risk of chronic graft-versus-host disease. Blood. 1997 Dec 15;90(12):4705-9. (1997) Abstract

Storb R, Leisenring W, Anasetti C, Appelbaum FR, Deeg HJ, Doney K, Martin P, Sullivan KM, Witherspoon R, Pettinger M, Bensinger W, Buckner CD, Clift R, Flowers ME, Hansen JA, Pepe M, Chauncey T, Sanders J, Thomas ED. Methotrexate and cyclosporine for graft-vs.-host disease prevention: what length of therapy with cyclosporine? Biol Blood Marrow Transplant. 1997 Oct;3(4):194-201. (1997) Abstract

Storb R, Leisenring W, Anasetti C, Appelbaum FR, Buckner CD, Bensinger WI, Chauncey T, Clift RA, Deeg HJ, Doney KC, Flowers ME, Hansen JA, Martin PJ, Sanders JE, Sullivan KM, Witherspoon RP. Long-term follow-up of allogeneic marrow transplants in patients with aplastic anemia conditioned by cyclophosphamide combined with antithymocyte globulin. Blood. 1997 May 15;89(10):3890-1. (1997) Abstract

Sierra J, Storer B, Hansen JA, Bjerke JW, Martin PJ, Petersdorf EW, Appelbaum FR, Bryant E, Chauncey TR, Sale G, Sanders JE, Storb R, Sullivan KM, Anasetti C. Transplantation of marrow cells from unrelated donors for treatment of high-risk acute leukemia: the effect of leukemic burden, donor HLA-matching, and marrow cell dose. Blood. 1997 Jun 1;89(11):4226-35. (1997) Abstract

Sierra J, Radich J, Hansen JA, Martin PJ, Petersdorf EW, Bjerke J, Bryant E, Nash RA, Sanders JE, Storb R, Sullivan KM, Appelbaum FR, Anasetti C. Marrow transplants from unrelated donors for treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood. 1997 Aug 15;90(4):1410-4. (1997) Abstract

Nelson JL, Torrez R, Louie FM, Choe OS, Storb R, Sullivan KM. Pre-existing autoimmune disease in patients with long-term survival after allogeneic bone marrow transplantation. J Rheumatol Suppl. 1997 May;48:23-9. (1997) Abstract

Nash RA, McSweeney PA, Storb R, Nelson JL, Gauthier J, Furst DE, Sullivan KM. Development of a protocol for allogeneic marrow transplantation for severe systemic sclerosis: paradigm for autoimmune disease. J Rheumatol Suppl. 1997 May;48:72-8. (1997) Abstract

McSweeney PA, Nash RA, Storb R, Furst DE, Gauthier J, Sullivan KM. Autologous stem cell transplantation for autoimmune diseases: issues in protocol development. J Rheumatol Suppl. 1997 May;48:79-84. (1997) Abstract

Deeg HJ, Lin D, Leisenring W, Boeckh M, Anasetti C, Appelbaum FR, Chauncey TR, Doney K, Flowers M, Martin P, Nash R, Schoch G, Sullivan KM, Witherspoon RP, Storb R. Cyclosporine or cyclosporine plus methylprednisolone for prophylaxis of graft-versus-host disease: a prospective, randomized trial. Blood. 1997 May 15;89(10):3880-7. (1997) Abstract

Chen CS, Seidel K, Armitage JO, Fay JW, Appelbaum FR, Horowitz MM, Shpall EJ, Weiden PL, Antman KS, Champlin RE, Kersey JH, Sullivan KM. Safeguarding the administration of high-dose chemotherapy: a national practice survey by the American Society for Blood and Marrow Transplantation. Biol Blood Marrow Transplant. 1997 Dec;3(6):331-40. (1997) Abstract

Charuhas PM, Fosberg KL, Bruemmer B, Aker SN, Leisenring W, Seidel K, Sullivan KM. A double-blind randomized trial comparing outpatient parenteral nutrition with intravenous hydration: effect on resumption of oral intake after marrow transplantation. JPEN J Parenter Enteral Nutr. 1997 May-Jun;21(3):157-61. (1997) Abstract

Walters MC, Patience M, Leisenring W, Eckman JR, Scott JP, Mentzer WC, Davies SC, Ohene-Frempong K, Bernaudin F, Matthews DC, Storb R, Sullivan KM. Bone marrow transplantation for sickle cell disease. N Engl J Med. 1996 Aug 8;335(6):369-76. (1996) Abstract

Walters MC, Patience M, Leisenring W, Eckman JR, Buchanan GR, Rogers ZR, Olivieri NE, Vichinsky E, Davies SC, Mentzer WC, Powars D, Scott JP, Bernaudin F, Ohene-Frempong K, Darbyshire PJ, Wayne A, Roberts IA, Dinndorf P, Brandalise S, Sanders JE, Matthews DC, Appelbaum FR, Storb R, Sullivan KM. Barriers to bone marrow transplantation for sickle cell anemia. Biol Blood Marrow Transplant. 1996 May;2(2):100-4. (1996) Abstract

Wagner JL, Deeg HJ, Seidel K, Anasetti C, Doney K, Sanders J, Sullivan KM, Storb R. Bone marrow transplantation for severe aplastic anemia from genotypically HLA-nonidentical relatives. An update of the Seattle experience. Transplantation. 1996 Jan 15;61(1):54-61. (1996) Abstract

Sullivan KM. Secondary immunodeficiencies and stem cell transplantation: issues of administration and safety of intravenous immunoglobulin. Clin Ther. 1996;18 Suppl B:126-36. (1996) Abstract

Sullivan KM. Immunomodulation in allogeneic marrow transplantation: use of intravenous immune globulin to suppress acute graft-versus-host disease. Clin Exp Immunol. 1996 May;104 Suppl 1:43-8. (1996) Abstract

Sullivan KM, Storek J, Kopecky KJ, Jocom J, Longton G, Flowers M, Siadak M, Nims J, Witherspoon RP, Anasetti C, Appelbaum FR, Bowden RA, Buckner CD, Crawford SW, Deeg HJ, Hansen JA, McDonald GB, Sanders JE, Storb R. A controlled trial of long-term administration of intravenous immunoglobulin to prevent late infection and chronic graft-vs.-host disease after marrow transplantation: clinical outcome and effect on subsequent immune recovery. Biol Blood Marrow Transplant. 1996 Feb;2(1):44-53. (1996) Abstract

Stern JM, Chesnut CH 3rd, Bruemmer B, Sullivan KM, Lenssen PS, Aker SN, Sanders J. Bone density loss during treatment of chronic GVHD. Bone Marrow Transplant. 1996 Mar;17(3):395-400. (1996) Abstract

Nash RA, Piñeiro LA, Storb R, Deeg HJ, Fitzsimmons WE, Furlong T, Hansen JA, Gooley T, Maher RM, Martin P, McSweeney PA, Sullivan KM, Anasetti C, Fay JW. FK506 in combination with methotrexate for the prevention of graft-versus-host disease after marrow transplantation from matched unrelated donors. Blood. 1996 Nov 1;88(9):3634-41. (1996) Abstract

Martin PJ, Nelson BJ, Appelbaum FR, Anasetti C, Deeg HJ, Hansen JA, McDonald GB, Nash RA, Sullivan KM, Witherspoon RP, Scannon PJ, Friedmann N, Storb R. Evaluation of a CD5-specific immunotoxin for treatment of acute graft-versus-host disease after allogeneic marrow transplantation. Blood. 1996 Aug 1;88(3):824-30. (1996) Abstract

Langston AA, Sanders JE, Deeg HJ, Crawford SW, Anasetti C, Sullivan KM, Flowers ME, Storb R. Allogeneic marrow transplantation for aplastic anaemia associated with dyskeratosis congenita. Br J Haematol. 1996 Mar;92(3):758-65. (1996) Abstract

Kiem HP, McDonald GB, Myerson D, Spurgeon CL, Deeg HJ, Sanders JE, Doney K, Appelbaum FR, Sullivan KM, Witherspoon RP, Storb R. Marrow transplantation for hepatitis-associated aplastic anemia: a follow-up of long-term survivors. Biol Blood Marrow Transplant. 1996 May;2(2):93-9. (1996) Abstract

Flowers ME, Sullivan KM, Deeg HJ. Graft-versus-host reactions: anti-leukemia effects of donor T cells. Transplant Proc. 1996 Jun;28(3):1184-5. (1996) Abstract

Deeg HJ, Socié G, Schoch G, Henry-Amar M, Witherspoon RP, Devergie A, Sullivan KM, Gluckman E, Storb R. Malignancies after marrow transplantation for aplastic anemia and fanconi anemia: a joint Seattle and Paris analysis of results in 700 patients. Blood. 1996 Jan 1;87(1):386-92. (1996) Abstract

Anderson JE, Appelbaum FR, Schoch G, Gooley T, Anasetti C, Bensinger WI, Bryant E, Buckner CD, Chauncey TR, Clift RA, Doney K, Flowers M, Hansen JA, Martin PJ, Matthews DC, Sanders JE, Shulman H, Sullivan KM, Witherspoon RP, Storb R. Allogeneic marrow transplantation for refractory anemia: a comparison of two preparative regimens and analysis of prognostic factors. Blood. 1996 Jan 1;87(1):51-8. (1996) Abstract

Anderson JE, Anasetti C, Appelbaum FR, Schoch G, Gooley TA, Hansen JA, Buckner CD, Sanders JE, Sullivan KM, Storb R. Unrelated donor marrow transplantation for myelodysplasia (MDS) and MDS-related acute myeloid leukaemia. Br J Haematol. 1996 Apr;93(1):59-67. (1996) Abstract

Walters MC, Sullivan KM, Bernaudin F, Souillet G, Vannier JP, Johnson FL, Lenarsky C, Powars D, Bunin N, Ohene-Frempong K. Neurologic complications after allogeneic marrow transplantation for sickle cell anemia. Blood. 1995 Feb 15;85(4):879-84. (1995) Abstract

Kalhs P, Schwarzinger I, Anderson G, Mori M, Clift RA, Storb R, Buckner CD, Appelbaum FR, Hansen JA, Sullivan KM. A retrospective analysis of the long-term effect of splenectomy on late infections, graft-versus-host disease, relapse, and survival after allogeneic marrow transplantation for chronic myelogenous leukemia. Blood. 1995 Sep 1;86(5):2028-32. (1995) Abstract

Doney KC, Storb R, Beach K, Anasetti C, Deeg HJ, Hansen JA, Martin PJ, Nash RA, Schubert MM, Sullivan KM. A toxicity study of trimetrexate used in combination with cyclosporine as acute graft-versus-host disease prophylaxis in HLA-mismatched, related donor bone marrow transplants. Transplantation. 1995 Jul 15;60(1):55-8. (1995) Abstract

Bush NE, Haberman M, Donaldson G, Sullivan KM. Quality of life of 125 adults surviving 6-18 years after bone marrow transplantation. Soc Sci Med. 1995 Feb;40(4):479-90. (1995) Abstract

Benyunes MC, Sullivan KM, Deeg HJ, Mori M, Meyer W, Fisher L, Bensinger R, Jack MK, Hicks J, Witherspoon R. Cataracts after bone marrow transplantation: long-term follow-up of adults treated with fractionated total body irradiation. Int J Radiat Oncol Biol Phys. 1995 Jun 15;32(3):661-70. (1995) Abstract

Walters MC, Sullivan KM, O'Reilly RJ, Boulad F, Brockstein J, Blume K, Amylon M, Johnson FL, Klemperer M, Graham-Pole J. Bone marrow transplantation for thalassemia. The USA experience. Am J Pediatr Hematol Oncol. 1994 Feb;16(1):11-7. (1994) Abstract

Siadak MF, Kopecky K, Sullivan KM. Reduction in transplant-related complications in patients given intravenous immuno globulin after allogeneic marrow transplantation. Clin Exp Immunol. 1994 Jul;97 Suppl 1:53-7. (1994) Abstract

Siadak M, Sullivan KM. The management of chronic graft-versus-host disease. Blood Rev. 1994 Sep;8(3):154-60. (1994) Abstract

Seidler CW, Mills LE, Flowers ME, Sullivan KM. Spontaneous factor VIII inhibitor occurring in association with chronic graft-versus-host disease. Am J Hematol. 1994 Mar;45(3):240-3. (1994) Abstract

Sanders JE, Storb R, Anasetti C, Deeg HJ, Doney K, Sullivan KM, Witherspoon RP, Hansen J. Marrow transplant experience for children with severe aplastic anemia. Am J Pediatr Hematol Oncol. 1994 Feb;16(1):43-9. (1994) Abstract

Robinson N, Sullivan KM. Complications of allogeneic bone marrow transplantation. Curr Opin Hematol. 1994 Nov;1(6):406-11. (1994) Abstract

Johnson FL, Mentzer WC, Kalinyak KA, Sullivan KM, Abboud MR. Bone marrow transplantation for sickle cell disease. The United States experience. Am J Pediatr Hematol Oncol. 1994 Feb;16(1):22-6. (1994) Abstract

Deeg HJ, Anasetti C, Petersdorf E, Storb R, Doney K, Hansen JA, Sanders J, Sullivan KM, Appelbaum FR. Cyclophosphamide plus ATG conditioning is insufficient for sustained hematopoietic reconstitution in patients with severe aplastic anemia transplanted with marrow from HLA-A, B, DRB matched unrelated donors. Blood. 1994 Jun 1;83(11):3417-8. (1994) Abstract

de Oliveira JS, Auerbach SB, Sullivan KM, Sale GE. Fatal eosinophilia myalgia syndrome in a marrow transplant patient attributed to total parenteral nutrition with a solution containing tryptophan. Bone Marrow Transplant. 1993 Feb;11(2):163-7. (1993) Abstract

Syrjala KL, Chapko MK, Vitaliano PP, Cummings C, Sullivan KM. Recovery after allogeneic marrow transplantation: prospective study of predictors of long-term physical and psychosocial functioning. Bone Marrow Transplant. 1993 Apr;11(4):319-27. (1993) Abstract

Sullivan KM. Marrow transplantation for disorders of hematopoiesis. Leukemia. 1993 Jul;7(7):1098-9. (1993) Abstract

Haberman M, Bush N, Young K, Sullivan KM. Quality of life of adult long-term survivors of bone marrow transplantation: a qualitative analysis of narrative data. Oncol Nurs Forum. 1993 Nov-Dec;20(10):1545-53. (1993) Abstract

Greinix HT, Storb R, Sanders JE, Deeg HJ, Doney KC, Sullivan KM, Witherspoon RP. Long-term survival and cure after marrow transplantation for congenital hypoplastic anaemia (Diamond-Blackfan syndrome). Br J Haematol. 1993 Jul;84(3):515-20. (1993) Abstract

Witherspoon RP, Storb R, Pepe M, Longton G, Sullivan KM. Cumulative incidence of secondary solid malignant tumors in aplastic anemia patients given marrow grafts after conditioning with chemotherapy alone. Blood. 1992 Jan 1;79(1):289-91. (1992) Abstract

Tanaka K, Aki T, Shulman HM, Sullivan KM, Tanaka A, Nagasako R. Two cases of transfusion-associated graft-vs-host disease after open heart surgery. Arch Dermatol. 1992 Nov;128(11):1503-6. (1992) Abstract

Sullivan KM, Mori M, Sanders J, Siadak M, Witherspoon RP, Anasetti C, Appelbaum FR, Bensinger W, Bowden R, Buckner CD. Late complications of allogeneic and autologous marrow transplantation. Bone Marrow Transplant. 1992;10 Suppl 1:127-34. (1992) Abstract

Storb R, Martin P, Deeg HJ, Sanders JE, Pepe M, Singer J, Anasetti C, Stewart P, Appelbaum FR, Sullivan KM. Long-term follow-up of three controlled trials comparing cyclosporine versus methotrexate for graft-versus-host disease prevention in patients given marrow grafts for leukemia. Blood. 1992 Jun 1;79(11):3091-2. (1992) Abstract

Petersen FB, Deeg HJ, Buckner CD, Appelbaum FR, Storb R, Clift RA, Sanders JE, Bensinger WI, Witherspoon RP, Sullivan KM. Marrow transplantation following escalating doses of fractionated total body irradiation and cyclophosphamide--a phase I trial. Int J Radiat Oncol Biol Phys. 1992;23(5):1027-32. (1992) Abstract

Petersen FB, Buckner CD, Appelbaum FR, Sanders JE, Bensinger WI, Storb R, Deeg HJ, Witherspoon RP, Sullivan KM, Clift RA. Etoposide, cyclophosphamide and fractionated total body irradiation as a preparative regimen for marrow transplantation in patients with advanced hematological malignancies: a phase I study. Bone Marrow Transplant. 1992 Jul;10(1):83-8. (1992) Abstract

Fried RH, Murakami CS, Fisher LD, Willson RA, Sullivan KM, McDonald GB. Ursodeoxycholic acid treatment of refractory chronic graft-versus-host disease of the liver. Ann Intern Med. 1992 Apr 15;116(8):624-9. (1992) Abstract

Flowers ME, Doney KC, Storb R, Deeg HJ, Sanders JE, Sullivan KM, Bryant E, Witherspoon RP, Appelbaum FR, Buckner CD. Marrow transplantation for Fanconi anemia with or without leukemic transformation: an update of the Seattle experience. Bone Marrow Transplant. 1992 Mar;9(3):167-73. (1992) Abstract

Deeg HJ, Erickson K, Storb R, Sullivan KM. Photoinactivation of lymphohemopoietic cells: studies in transfusion medicine and bone marrow transplantation. Blood Cells. 1992;18(1):151-61; discussion 161-2. (1992) Abstract

DeGast GC, Mickelson EM, Beatty PG, Amos D, Sullivan KM, Schoch HG, Thomas ED, Hansen JA. Mixed leukocyte culture reactivity and graft-versus-host disease in HLA-identical marrow transplantation for leukemia. Bone Marrow Transplant. 1992 Feb;9(2):87-90. (1992) Abstract

Clift RA, Buckner CD, Appelbaum FR, Schoch G, Petersen FB, Bensinger WI, Sanders J, Sullivan KM, Storb R, Singer J. Allogeneic marrow transplantation during untreated first relapse of acute myeloid leukemia. J Clin Oncol. 1992 Nov;10(11):1723-9. (1992) Abstract

Anasetti C, Martin PJ, Storb R, Appelbaum FR, Beatty PG, Davis J, Doney K, Hill HF, Stewart P, Sullivan KM. Treatment of acute graft-versus-host disease with a nonmitogenic anti-CD3 monoclonal antibody. Transplantation. 1992 Nov;54(5):844-51. (1992) Abstract

deGast GC, Beatty PG, Amos D, Mickelson EM, Sullivan KM, Anderson JE, Giblett ER, Appelbaum F, Storb R, Deeg HJ. Transfusions shortly before HLA-matched marrow transplantation for leukemia are associated with a decrease in chronic graft-versus-host disease. Bone Marrow Transplant. 1991 Apr;7(4):293-5. (1991) Abstract

Van der Jagt RH, Appelbaum FR, Petersen FB, Bigelow CL, Fisher LD, Schoch GH, Buckner CD, Sanders JE, Storb R, Sullivan KM. Busulfan and cyclophosphamide as a preparative regimen for bone marrow transplantation in patients with prior chest radiotherapy. Bone Marrow Transplant. 1991 Sep;8(3):211-5. (1991) Abstract

Tanaka K, Sullivan KM, Shulman HM, Sale GE, Tanaka A. A clinical review: cutaneous manifestations of acute and chronic graft-versus-host disease following bone marrow transplantation. J Dermatol. 1991 Jan;18(1):11-7. (1991) Abstract

Sullivan KM, Reid CD. Introduction to a symposium on sickle cell anemia: current results of comprehensive care and the evolving role of bone marrow transplantation. Semin Hematol. 1991 Jul;28(3):177-9. (1991) Abstract

Sullivan KM, Agura E, Anasetti C, Appelbaum F, Badger C, Bearman S, Erickson K, Flowers M, Hansen J, Loughran T. Chronic graft-versus-host disease and other late complications of bone marrow transplantation. Semin Hematol. 1991 Jul;28(3):250-9. (1991) Abstract

Nemunaitis J, Singer JW, Buckner CD, Mori T, Laponi J, Hill R, Storb R, Sullivan KM, Hansen JA, Appelbaum FR. Long-term follow-up of patients who received recombinant human granulocyte-macrophage colony stimulating factor after autologous bone marrow transplantation for lymphoid malignancy. Bone Marrow Transplant. 1991 Jan;7(1):49-52. (1991) Abstract

Sullivan KM. Chronic graft-versus-host disease. Cancer Treat Res. 1990;50:79-98. (1990) Abstract

Sullivan KM, Meyers J, Petersen FB, Bowden R, Counts GC, Banaji M, Schubert M, Clark J, Clift RA, Appelbaum FR. Supportive care of the marrow transplant recipient: the Seattle Experience. Hamatol Bluttransfus. 1990;33:539-45. (1990) Abstract

Sullivan KM, Kopecky KJ, Jocom J, Fisher L, Buckner CD, Meyers JD, Counts GW, Bowden RA, Peterson FB, Witherspoon RP. Immunomodulatory and antimicrobial efficacy of intravenous immunoglobulin in bone marrow transplantation. N Engl J Med. 1990 Sep 13;323(11):705-12. (1990) Abstract

Sullivan KM, Appelbaum FR. Comparative trials of chemotherapy and bone marrow transplantation in acute nonlymphocytic leukemia. Rinsho Ketsueki. 1990 May;31(5):527-33. (1990) Abstract

Storb R, Pepe M, Anasetti C, Appelbaum FR, Beatty P, Doney K, Martin P, Stewart P, Sullivan KM, Witherspoon R. What role for prednisone in prevention of acute graft-versus-host disease in patients undergoing marrow transplants? Blood. 1990 Sep 1;76(5):1037-45. (1990) Abstract

Schubert MM, Sullivan KM. Recognition, incidence, and management of oral graft-versus-host disease. NCI Monogr. 1990;(9):135-43. (1990) Abstract

Petersen FB, Appelbaum FR, Hill R, Fisher LD, Bigelow CL, Sanders JE, Sullivan KM, Bensinger WI, Witherspoon RP, Storb R. Autologous marrow transplantation for malignant lymphoma: a report of 101 cases from Seattle. J Clin Oncol. 1990 Apr;8(4):638-47. (1990) Abstract

Lenssen P, Sherry ME, Cheney CL, Nims JW, Sullivan KM, Stern JM, Moe G, Aker SN. Prevalence of nutrition-related problems among long-term survivors of allogeneic marrow transplantation. J Am Diet Assoc. 1990 Jun;90(6):835-42. (1990) Abstract

Hill HF, Chapman CR, Kornell JA, Sullivan KM, Saeger LC, Benedetti C. Self-administration of morphine in bone marrow transplant patients reduces drug requirement. Pain. 1990 Feb;40(2):121-9. (1990) Abstract

Higano CS, Brixey M, Bryant EM, Durnam DM, Doney K, Sullivan KM, Singer JW. Durable complete remission of acute nonlymphocytic leukemia associated with discontinuation of immunosuppression following relapse after allogeneic bone marrow transplantation. A case report of a probable graft-versus-leukemia effect. Transplantation. 1990 Jul;50(1):175-7. (1990) Abstract

Flowers ME, Pepe MS, Longton G, Doney KC, Monroe D, Witherspoon RP, Sullivan KM, Storb R. Previous donor pregnancy as a risk factor for acute graft-versus-host disease in patients with aplastic anaemia treated by allogeneic marrow transplantation. Br J Haematol. 1990 Apr;74(4):492-6. (1990) Abstract

Sullivan KM. Intravenous immune globulin prophylaxis in recipients of a marrow transplant. J Allergy Clin Immunol. 1989 Oct;84(4 Pt 2):632-8; discussion 638-9. (1989) Abstract

Sullivan KM. Congress review: progress and prospects in bone marrow transplantation. Transplant Proc. 1989 Feb;21(1 Pt 3):2919-22. (1989) Abstract

Sullivan KM, Witherspoon RP, Storb R, Buckner CD, Sanders J, Thomas ED. Long-term results of allogeneic bone marrow transplantation. Transplant Proc. 1989 Feb;21(1 Pt 3):2926-8. (1989) Abstract

Sullivan KM, Weiden PL, Storb R, Witherspoon RP, Fefer A, Fisher L, Buckner CD, Anasetti C, Appelbaum FR, Badger C. Influence of acute and chronic graft-versus-host disease on relapse and survival after bone marrow transplantation from HLA-identical siblings as treatment of acute and chronic leukemia. Blood. 1989 May 1;73(6):1720-8. (1989) Abstract

Sullivan KM, Storb R, Buckner CD, Fefer A, Fisher L, Weiden PL, Witherspoon RP, Appelbaum FR, Banaji M, Hansen J. Graft-versus-host disease as adoptive immunotherapy in patients with advanced hematologic neoplasms. N Engl J Med. 1989 Mar 30;320(13):828-34. (1989) Abstract

Hill HF, Chapman CR, Jackson TL, Sullivan KM. Assessment and management of donor pain following marrow harvest for allogeneic bone marrow transplantation. Bone Marrow Transplant. 1989 Mar;4(2):157-61. (1989) Abstract

Chapko MK, Syrjala KL, Schilter L, Cummings C, Sullivan KM. Chemoradiotherapy toxicity during bone marrow transplantation: time course and variation in pain and nausea. Bone Marrow Transplant. 1989 Mar;4(2):181-6. (1989) Abstract