Joseph Geradts, MD, MA
Department / Division
Pathology /
Pathology Clinical Services
Address
DUMC 3712
Durham, NC 27710
Office Telephone
919-668-5670
Fax Telephone
919-684-8693
- MD, University of Chicago Pritzker School of Medicine (Illinois), 1987
- Anatomic Pathology, UCSF Hospitals (California), 1987-1989
- Surgical Pathology, Stanford University Medical Center (California), 1989-1990
- MA, Endocrinology, University of California, Berkeley, 1984
Clinical Interests
Surgical and oncologic pathology, breast pathology including prognostic and predictive markers
Research Interests
Dr. Geradts' primary research focus is on the molecular pathology of breast cancer. His laboratory uses genomic profiling strategies to identify novel candidate breast cancer genes. Dr. Geradts is also interested in biomarker development. He directs the Tissue Core of Duke's Breast Cancer SPORE and collaborates on numerous breast cancer related research projects with other investigators at Duke and elsewhere.
This physician has no reported relationships with industry.
Representative Publications
Barry WT, Kernagis DN, Dressman HK, Griffis RJ, Hunter JD, Olson JA, Marks JR, Ginsburg GS, Marcom PK, Nevins JR, Geradts J, Datto MB. Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome. J Clin Oncol. 2010 May 1;28(13):2198-206.
(2010)
Abstract
Brown JQ, Wilke LG, Geradts J, Kennedy SA, Palmer GM, Ramanujam N. Quantitative optical spectroscopy: a robust tool for direct measurement of breast cancer vascular oxygenation and total hemoglobin content in vivo. Cancer Res. 2009 Apr 1;69(7):2919-26.
(2009)
Abstract
Ramanujam N, Brown J, Bydlon TM, Kennedy SA, Richards LM, Junker MK, Gallagher J, Barry WT, Wilke LG, Geradts J. Quantitative spectral reflectance imaging device for intraoperative breast tumor margin assessment. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6554-6.
(2009)
Abstract
Sood AK, Wang J, Mhawech-Fauceglia P, Jana B, Liang P, Geradts J. Sam-pointed domain containing Ets transcription factor in luminal breast cancer pathogenesis. Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1899-903.
(2009)
Abstract
Millikan RC, Newman B, Tse CK, Moorman PG, Conway K, Dressler LG, Smith LV, Labbok MH, Geradts J, Bensen JT, Jackson S, Nyante S, Livasy C, Carey L, Earp HS, Perou CM. Epidemiology of basal-like breast cancer. Breast Cancer Res Treat. 2008 May;109(1):123-39.
(2008)
Abstract
Huang H, Sossey-Alaoui K, Beachy SH, Geradts J. The tetraspanin superfamily member NET-6 is a new tumor suppressor gene. J Cancer Res Clin Oncol. 2007 Oct;133(10):761-9.
(2007)
Abstract
Sood AK, Saxena R, Groth J, Desouki MM, Cheewakriangkrai C, Rodabaugh KJ, Kasyapa CS, Geradts J. Expression characteristics of prostate-derived Ets factor support a role in breast and prostate cancer progression. Hum Pathol. 2007 Nov;38(11):1628-38.
(2007)
Abstract
Carey LA, Perou CM, Livasy CA, Dressler LG, Cowan D, Conway K, Karaca G, Troester MA, Tse CK, Edmiston S, Deming SL, Geradts J, Cheang MC, Nielsen TO, Moorman PG, Earp HS, Millikan RC. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA. 2006 Jun 7;295(21):2492-502.
(2006)
Abstract
Huang H, Groth J, Sossey-Alaoui K, Hawthorn L, Beall S, Geradts J. Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors. Clin Cancer Res. 2005 Jun 15;11(12):4357-64.
(2005)
Abstract
Varma G, Varma R, Huang H, Pryshchepava A, Groth J, Fleming D, Nowak NJ, McQuaid D, Conroy J, Mahoney M, Moysich K, Falkner KL, Geradts J. Array comparative genomic hybridisation (aCGH) analysis of premenopausal breast cancers from a nuclear fallout area and matched cases from Western New York. Br J Cancer. 2005 Sep 19;93(6):699-708.
(2005)
Abstract
Geradts J. Abrogation of the RB-p16 tumor suppressor pathway in human lung cancer. Methods Mol Med. 2003;74:89-99.
(2003)
Abstract
Wilson KS, Roberts H, Leek R, Harris AL, Geradts J. Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues. Am J Pathol. 2002 Oct;161(4):1171-85.
(2002)
Abstract
