Joseph Geradts, MD, MA
Department / Division
Pathology /
Pathology Clinical Services
Address
DUMC 3712
Durham, NC 27710
Office Telephone
919-668-5670
Fax Telephone
919-684-8693
- MD, University of Chicago Pritzker School of Medicine (Illinois), 1987
- Anatomic Pathology, University of California–San Francisco Hospitals, 1987-1989
- Surgical Pathology, Stanford University Medical Center (California), 1989-1990
- MA, Endocrinology, University of California–Berkeley, 1984
Clinical Interests
Surgical and oncologic pathology, breast pathology including prognostic and predictive markers
Research Interests
Dr. Geradts' primary research focus is on the molecular pathology of breast cancer. His laboratory uses genomic profiling strategies to identify novel candidate breast cancer genes. Dr. Geradts is also interested in biomarker development. He directs the Tissue Core of Duke's Breast Cancer SPORE and collaborates on numerous breast cancer related research projects with other investigators at Duke and elsewhere.
This faculty member has no reported relationships with industry.
Representative Publications
Barry, WT; Kernagis, DN; Dressman, HK; Griffis, RJ; Hunter, JD; Olson, JA; Marks, JR; Ginsburg, GS; Marcom, PK; Nevins, JR; Geradts, J; Datto, MB. Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome. Journal of Clinical Oncology. 2010;28:2198-2206.
(2010)
Abstract
Brown, JQ; Wilke, LG; Geradts, J; Kennedy, SA; Palmer, GM; Ramanujam, N. Quantitative optical spectroscopy: a robust tool for direct measurement of breast cancer vascular oxygenation and total hemoglobin content in vivo. Cancer Research. 2009;69:2919-2926.
(2009)
Abstract
Ramanujam, N; Brown, J; Bydlon, TM; Kennedy, SA; Richards, LM; Junker, MK; Gallagher, J; Barry, WT; Wilke, LG; Geradts, J. Quantitative spectral reflectance imaging device for intraoperative breast tumor margin assessment. 2009;2009:6554-6556.
(2009)
Abstract
Sood, AK; Wang, J; Mhawech-Fauceglia, P; Jana, B; Liang, P; Geradts, J. Sam-pointed domain containing Ets transcription factor in luminal breast cancer pathogenesis. Cancer Epidemiology, Biomarkers and Prevention. 2009;18:1899-1903.
(2009)
Abstract
Millikan, RC; Newman, B; Tse, CK; Moorman, PG; Conway, K; Dressler, LG; Smith, LV; Labbok, MH; Geradts, J; Bensen, JT; Jackson, S; Nyante, S; Livasy, C; Carey, L; Earp, HS; Perou, CM. Epidemiology of basal-like breast cancer. Breast Cancer Research and Treatment. 2008;109:123-139.
(2008)
Abstract
Huang, H; Sossey-Alaoui, K; Beachy, SH; Geradts, J. The tetraspanin superfamily member NET-6 is a new tumor suppressor gene. Journal of Cancer Research and Clinical Oncology. 2007;133:761-769.
(2007)
Abstract
Sood, AK; Saxena, R; Groth, J; Desouki, MM; Cheewakriangkrai, C; Rodabaugh, KJ; Kasyapa, CS; Geradts, J. Expression characteristics of prostate-derived Ets factor support a role in breast and prostate cancer progression. Human Pathology. 2007;38:1628-1638.
(2007)
Abstract
Carey, LA; Perou, CM; Livasy, CA; Dressler, LG; Cowan, D; Conway, K; Karaca, G; Troester, MA; Tse, CK; Edmiston, S; Deming, SL; Geradts, J; Cheang, MC; Nielsen, TO; Moorman, PG; Earp, HS; Millikan, RC. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA: Journal of the American Medical Association. 2006;295:2492-2502.
(2006)
Abstract
Huang, H; Groth, J; Sossey-Alaoui, K; Hawthorn, L; Beall, S; Geradts, J. Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors. Clinical Cancer Research. 2005;11:4357-4364.
(2005)
Abstract
Varma, G; Varma, R; Huang, H; Pryshchepava, A; Groth, J; Fleming, D; Nowak, NJ; McQuaid, D; Conroy, J; Mahoney, M; Moysich, K; Falkner, KL; Geradts, J. Array comparative genomic hybridisation (aCGH) analysis of premenopausal breast cancers from a nuclear fallout area and matched cases from Western New York. British Journal of Cancer. 2005;93:699-708.
(2005)
Abstract
Geradts, J. Abrogation of the RB-p16 tumor suppressor pathway in human lung cancer. Methods in Molecular Medicine. 2003;74:89-99.
(2003)
Abstract
Wilson, KS; Roberts, H; Leek, R; Harris, AL; Geradts, J. Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues. American Journal of Pathology. 2002;161:1171-1185.
(2002)
Abstract
