Joseph Geradts, MD, MA

Department / Division:
Pathology

Address:
DUMC 3712
Durham, NC 27710

Office Telephone:
919-668-5670

Fax Telephone:
919-684-8693

• MD, University of Chicago Pritzker School of Medicine (Illinois), 1987

• Anatomic Pathology, University of California, San Francisco, 1987-1989

• Surgical Pathology, Stanford University Medical Center (California), 1989-1990

• MA, Endocrinology, University of California, Berkeley, 1984

Clinical Interests:
Surgical and oncologic pathology, breast pathology including prognostic and predictive markers

Research Interests:
Dr. Geradts' primary research focus is on the molecular pathology of breast cancer.  His laboratory uses genomic profiling strategies to identify novel candidate breast cancer genes.  Dr. Geradts is also interested in biomarker development.  He directs the Tissue Core of Duke's Breast Cancer SPORE and collaborates on numerous breast cancer related research projects with other investigators at Duke and elsewhere.

Representative Publications:
Huang H, Sossey-Alaoui K, Beachy SH, Geradts J. The tetraspanin superfamily member NET-6 is a new tumor suppressor gene. J Cancer Res Clin Oncol. 2007 May 8. (2007) Abstract

Varma G, Varma R, Huang H, Pryshchepava A, Groth J, Fleming D, Nowak NJ, McQuaid D, Conroy J, Mahoney M, Moysich K, Falkner KL, Geradts J. Array comparative genomic hybridisation (aCGH) analysis of premenopausal breast cancers from a nuclear fallout area and matched cases from Western New York. Br J Cancer. 2005 Sep 19;93(6):699-708. (2005) Abstract

Huang H, Groth J, Sossey-Alaoui K, Hawthorn L, Beall S, Geradts J. Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors. Clin Cancer Res. 2005 Jun 15;11(12):4357-64. (2005) Abstract

Geradts J. Abrogation of the RB-p16 tumor suppressor pathway in human lung cancer. Methods Mol Med. 2003;74:89-99. (2003) Abstract

Wilson KS, Roberts H, Leek R, Harris AL, Geradts J. Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues. Am J Pathol. 2002 Oct;161(4):1171-85. (2002) Abstract