John S. March, MD, MPH
Director, Division of Neurosciences Medicine, Duke Clinical Research Institute
Department / Division
Psychiatry /
Child & Adolescent Psychiatry
Address
DUMC 3850
Durham, NC 27710
Appointment Telephone
919-416-2430
Office Telephone
919-668-4644
Fax Telephone
919-668-7056
- MD, MPH, University of California, Los Angeles, David Geffen School of Medicine, 1978
- Family Practice, University of California, Los Angeles, 1978-1981
- Psychiatry, University of Wisconsin Health, 1986-1988
- Child Psychiatry, University of Wisconsin Health, 1988-1990
Clinical Interests
Clinical trials in adult and pediatric neurology, psychiatry, and pain; pediatric psychopharmacology, intervention, biomarkers/biosignatures
Research Interests
Dr. March is Professor of Psychiatry and Psychology and Director of the Division of Neurosciences Medicine at the Duke Clinical Research Institute. Dr. March develops, conducts and facilitates research projects in adult and child neurology and psychiatry that range from biomarker/biosignature development and validation, imaging genomics, Phase I-IV industry and Federal clinical trials, to outcomes research.
This physician (or a member of their immediate family) has a working relationship (i.e. consulting, research, and/or educational services) with the companies listed below. These relations have been reported to the health system leadership and, when appropriate, management plans are in place to address potential conflicts.
- Alkermes, Inc.
- Attention Therapeutics
- Avanir Pharmaceuticals
- Eli Lilly & Co.
- Guilford Publications
- MedAvante
- Multi-Health Systems Inc.
- Pfizer Inc.
- Psymetrix
- Vivus, Inc.
Representative Publications
March JS, Fegert JM. Drug Development in Pediatric Psychiatry: Current Status, Future Trends. Child Adolesc Psychiatry Ment Health. 2012 Feb 7;6(1):7.
(2012)
Abstract
Franklin ME, Sapyta J, Freeman JB, Khanna M, Compton S, Almirall D, Moore P, Choate-Summers M, Garcia A, Edson AL, Foa EB, March JS. Cognitive behavior therapy augmentation of pharmacotherapy in pediatric obsessive-compulsive disorder: the Pediatric OCD Treatment Study II (POTS II) randomized controlled trial. JAMA. 2011 Sep 21;306(11):1224-32.
(2011)
Abstract
Kratochvil CJ, Vaughan BS, Stoner JA, Daughton JM, Lubberstedt BD, Murray DW, Chrisman AK, Faircloth MA, Itchon-Ramos NB, Kollins SH, Maayan LA, Greenhill LL, Kotler LA, Fried J, March JS. A double-blind, placebo-controlled study of atomoxetine in young children with ADHD. Pediatrics. 2011 Apr;127(4):e862-8.
(2011)
Abstract
Leckman JF, March JS. Editorial: Developmental neuroscience comes of age. J Child Psychol Psychiatry. 2011 Apr;52(4):333-8.
(2011)
Abstract
March JS. Looking to the future of research in pediatric anxiety disorders. Depress Anxiety. 2011 Jan;28(1):88-98.
(2011)
Abstract
March JS. The preschool ADHD Treatment Study (PATS) as the culmination of twenty years of clinical trials in pediatric psychopharmacology. J Am Acad Child Adolesc Psychiatry. 2011 May;50(5):427-30.
(2011)
Abstract
March JS. Attention bias modification training and the new interventions research. Biol Psychiatry. 2010 Dec 1;68(11):978-9.
(2010)
Abstract
March JS. Commentary on 'Forum: use of antidepressants in children and adolescents'. Curr Opin Psychiatry. 2010 Jan;23(1):63-5.
(2010)
Abstract
Brent DA, Greenhill LL, Compton S, Emslie G, Wells K, Walkup JT, Vitiello B, Bukstein O, Stanley B, Posner K, Kennard BD, Cwik MF, Wagner A, Coffey B, March JS, Riddle M, Goldstein T, Curry J, Barnett S, Capasso L, Zelazny J, Hughes J, Shen S, Gugga SS, Turner JB. The Treatment of Adolescent Suicide Attempters study (TASA): predictors of suicidal events in an open treatment trial. J Am Acad Child Adolesc Psychiatry. 2009 Oct;48(10):987-96.
(2009)
Abstract
March JS, Vitiello B. Benefits exceed risks of newer antidepressant medications in youth--maybe. Clin Pharmacol Ther. 2009 Oct;86(4):355-7.
(2009)
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March JS, Vitiello B. Clinical messages from the Treatment for Adolescents With Depression Study (TADS). Am J Psychiatry. 2009 Oct;166(10):1118-23.
(2009)
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March JS. The future of psychotherapy for mentally ill children and adolescents. J Child Psychol Psychiatry. 2009 Jan;50(1-2):170-9.
(2009)
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Shapiro M, Silva SG, Compton S, Chrisman A, DeVeaugh-Geiss J, Breland-Noble A, Kondo D, Kirchner J, March JS. The child and adolescent psychiatry trials network (CAPTN): infrastructure development and lessons learned. Child Adolesc Psychiatry Ment Health. 2009;3(1):12.
(2009)
Abstract
Vitiello B, Silva SG, Rohde P, Kratochvil CJ, Kennard BD, Reinecke MA, Mayes TL, Posner K, May DE, March JS. Suicidal events in the Treatment for Adolescents With Depression Study (TADS). J Clin Psychiatry. 2009 May;70(5):741-7.
(2009)
Abstract
Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown ES, Calabrese JR, Carlezon WA Jr, Cook EH Jr, Davidson RJ, Davis M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R, Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF, Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I, Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS, McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A, Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS, Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA, Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ, Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R, Yoshikawa T, Young EA, McCandless R. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biol Psychiatry. 2008 Apr 15;63(8):725-7.
(2008)
Abstract
Rohde P, Silva SG, Tonev ST, Kennard BD, Vitiello B, Kratochvil CJ, Reinecke MA, Curry JF, Simons AD, March JS. Achievement and maintenance of sustained response during the Treatment for Adolescents With Depression Study continuation and maintenance therapy. Arch Gen Psychiatry. 2008 Apr;65(4):447-55.
(2008)
Abstract
Walkup JT, Albano AM, Piacentini J, Birmaher B, Compton SN, Sherrill JT, Ginsburg GS, Rynn MA, McCracken J, Waslick B, Iyengar S, March JS, Kendall PC. Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety. N Engl J Med. 2008 Dec 25;359(26):2753-66.
(2008)
Abstract
Compton SN, Kratochvil CJ, March JS. Pharmacotherapy for anxiety disorders in children and adolescents: an evidence-based medicine review. Pediatr Ann. 2007 Sep;36(9):586-90, 592, 594-8.
(2007)
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Kollins SH, March JS. Advances in the pharmacotherapy of attention-deficit/hyperactivity disorder. Biol Psychiatry. 2007 Nov 1;62(9):951-3.
(2007)
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March JS, Entusah AR, Rynn M, Albano AM, Tourian KA. A Randomized controlled trial of venlafaxine ER versus placebo in pediatric social anxiety disorder. Biol Psychiatry. 2007 Nov 15;62(10):1149-54.
(2007)
Abstract
March JS, Franklin ME, Leonard H, Garcia A, Moore P, Freeman J, Foa E. Tics moderate treatment outcome with sertraline but not cognitive-behavior therapy in pediatric obsessive-compulsive disorder. Biol Psychiatry. 2007 Feb 1;61(3):344-7.
(2007)
Abstract
March JS, Silva S, Petrycki S, Curry J, Wells K, Fairbank J, Burns B, Domino M, McNulty S, Vitiello B, Severe J. The Treatment for Adolescents With Depression Study (TADS): long-term effectiveness and safety outcomes. Arch Gen Psychiatry. 2007 Oct;64(10):1132-43.
(2007)
Abstract
March JS, Szatmari P, Bukstein O, Chrisman A, Kondo D, Hamilton JD, Kremer CM, Kratochvil CJ. AACAP 2005 Research Forum: speeding the adoption of evidence-based practice in pediatric psychiatry. J Am Acad Child Adolesc Psychiatry. 2007 Sep;46(9):1098-110.
(2007)
Abstract
March JS, Klee BJ, Kremer CM. Treatment benefit and the risk of suicidality in multicenter, randomized, controlled trials of sertraline in children and adolescents. J Child Adolesc Psychopharmacol. 2006 Feb-Apr;16(1-2):91-102.
(2006)
Abstract
March JS, Chrisman A, Breland-Noble A, Clouse K, D'Alli R, Egger H, Gammon P, Gazzola M, Lin A, Mauro C, Rana A, Ravi H, Srirama M, Su H, Thrall G, van de Velde P, . Using and teaching evidence-based medicine: the Duke University child and adolescent psychiatry model. Child Adolesc Psychiatr Clin N Am. 2005 Apr;14(2):273-96, viii-ix.
(2005)
Abstract
March JS, Silva SG, Compton S, Shapiro M, Califf R, Krishnan R. The case for practical clinical trials in psychiatry. Am J Psychiatry. 2005 May;162(5):836-46.
(2005)
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March JS, Silva SG, Compton S, Anthony G, DeVeaugh-Geiss J, Califf R, Krishnan R. The Child and Adolescent Psychiatry Trials Network (CAPTN). J Am Acad Child Adolesc Psychiatry. 2004 May;43(5):515-8.
(2004)
Abstract
Greenhill LL, Vitiello B, Abikoff H, Levine J, March JS, Riddle MA, Capasso L, Cooper TB, Davies M, Fisher P, Findling RL, Fried J, Labellarte MJ, McCracken JT, McMahon D, Robinson J, Skrobala A, Scahill L, Varipatis E, Walkup JT, Zito JM. Developing methodologies for monitoring long-term safety of psychotropic medications in children: report on the NIMH conference, September 25, 2000. J Am Acad Child Adolesc Psychiatry. 2003 Jun;42(6):651-5.
(2003)
Abstract
Greenhill LL, Vitiello B, Riddle MA, Fisher P, Shockey E, March JS, Levine J, Fried J, Abikoff H, Zito JM, McCracken JT, Findling RL, Robinson J, Cooper TB, Davies M, Varipatis E, Labellarte MJ, Scahill L, Walkup JT, Capasso L, Rosengarten J. Review of safety assessment methods used in pediatric psychopharmacology. J Am Acad Child Adolesc Psychiatry. 2003 Jun;42(6):627-33.
(2003)
Abstract
March JS. Acute stress disorder in youth: a multivariate prediction model. Biol Psychiatry. 2003 May 1;53(9):809-16.
(2003)
Abstract
Costello EJ, Pine DS, Hammen C, March JS, Plotsky PM, Weissman MM, Biederman J, Goldsmith HH, Kaufman J, Lewinsohn PM, Hellander M, Hoagwood K, Koretz DS, Nelson CA, Leckman JF. Development and natural history of mood disorders. Biol Psychiatry. 2002 Sep 15;52(6):529-42.
(2002)
Abstract
March JS, Biederman J, Wolkow R, Safferman A, Mardekian J, Cook EH, Cutler NR, Dominguez R, Ferguson J, Muller B, Riesenberg R, Rosenthal M, Sallee FR, Wagner KD, Steiner H. Sertraline in children and adolescents with obsessive-compulsive disorder: a multicenter randomized controlled trial. JAMA. 1998 Nov 25;280(20):1752-6.
(1998)
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