Physicians

Department / Division
Anesthesiology / Anesthesiology-Hyperbaric Division

Address
DUMC 3823
Durham, NC 27710

Appointment Telephone
919-684-6726

Office Telephone
919-684-6726

Fax Telephone
919-684-6002

Training

• MD, University of Texas Southwestern Medical School, 1979

Residency

• Anesthesiology, Massachusetts General Hospital, 1983

Fellowship

• Critical Care Medicine, Massachusetts General Hospital, 1984
• Hyperbaric Medicine, Duke University Medical Center, 2001

Other Training

• MPH, University of North Carolina School of Public Health, 1999

Clinical Interests
Hyperbaric medicine, diving medicine, neuroprotection, wound healing

Research Interests
Dr Freiberger works on the translation of basic science research on reactive oxygen species signaling into clinical practice involving hyperbaric oxygen (HBO). He has performed animal experiments in the use of HBO for ischemic preconditioning and he is currently funded to conduct a randomized controlled trial of the use of HBO for the treatment of bisphosphonate-induced osteonecrosis of the jaw. The mechanisms of action for HBO in the treatment of: diabetic wounds, bony and soft tissue radionecrosis and decompression sickness are also areas of his inquiry. Dr Freiberger also does basic epidemiological research into accidents and injuries associated with diving, high altitude exposure and other adverse conditions associated with extreme environments. Dr. Freiberger directs the fellowship program at the Duke Center for Hyperbaric Medicine and Environmental Physiology.

Industry Relationships and Collaborations (What's this?)

This faculty member has no reported relationships with industry.

Representative Publications
Cherry, AD; Forkner, IF; Frederick, HJ; Natoli, MJ; Schinazi, EA; Longphre, JP; Conard, JL; White, WD; Freiberger, JJ; Stolp, BW; Pollock, NW; Doar, PO; Boso, AE; Alford, EL; Walker, AJ; Ma, AC; Rhodes, MA; Moon, RE. Predictors of increased PaCO2 during immersed prone exercise at 4.7 ATA. Journal of Applied Physiology. 2009;106:316-325. (2009) Abstract

Freiberger, JJ. Utility of hyperbaric oxygen in treatment of bisphosphonate-related osteonecrosis of the jaws. Journal of Oral and Maxillofacial Surgery. 2009;67:96-106. (2009) Abstract

Freiberger, JJ; Yoo, DS; de Lisle Dear, G; McGraw, TA; Blakey, GH; Padilla Burgos, R; Kraft, K; Nelson, JW; Moon, RE; Piantadosi, CA. Multimodality surgical and hyperbaric management of mandibular osteoradionecrosis. International Journal of Radiation: Oncology - Biology - Physics. 2009;75:717-724. (2009) Abstract

Vann, RD; Denoble, PJ; Howle, LE; Weber, PW; Freiberger, JJ; Pieper, CF. Resolution and severity in decompression illness. Aviation, Space, and Environmental Medicine. 2009;80:466-471. (2009) Abstract

Wester, TE; Cherry, AD; Pollock, NW; Freiberger, JJ; Natoli, MJ; Schinazi, EA; Doar, PO; Boso, AE; Alford, EL; Walker, AJ; Uguccioni, DM; Kernagis, D; Moon, RE. Effects of head and body cooling on hemodynamics during immersed prone exercise at 1 ATA. Journal of Applied Physiology. 2009;106:691-700. (2009) Abstract

Vann, RD; Moon, RE; Freiberger, JJ; Denoble, PJ; Dear, GL; Stolp, BW; Massey, EW. Decompression illness diagnosis and decompression study design. Aviation, Space, and Environmental Medicine. 2008;79:797-798. (2008) Abstract

Freiberger, JJ; Padilla-Burgos, R; Chhoeu, AH; Kraft, KH; Boneta, O; Moon, RE; Piantadosi, CA. Hyperbaric oxygen treatment and bisphosphonate-induced osteonecrosis of the jaw: a case series. Journal of Oral and Maxillofacial Surgery. 2007;65:1321-1327. (2007) Abstract

Longphre, JM; Denoble, PJ; Moon, RE; Vann, RD; Freiberger, JJ. First aid normobaric oxygen for the treatment of recreational diving injuries. Undersea and Hyperbaric Medicine. 2007;34:43-49. (2007) Abstract

Vann, RD; Pollock, NW; Freiberger, JJ; Natoli, MJ; Denoble, PJ; Pieper, CF. Influence of bottom time on preflight surface intervals before flying after diving. Undersea and Hyperbaric Medicine. 2007;34:211-220. (2007) Abstract

Freiberger, JJ; Suliman, HB; Sheng, H; McAdoo, J; Piantadosi, CA; Warner, DS. A comparison of hyperbaric oxygen versus hypoxic cerebral preconditioning in neonatal rats. Brain Research. 2006;1075:213-222. (2006) Abstract

Cronje, FJ; Carraway, MS; Freiberger, JJ; Suliman, HB; Piantadosi, CA. Carbon monoxide actuates O(2)-limited heme degradation in the rat brain. Free Radical Biology and Medicine. 2004;37:1802-1812. (2004) Abstract

Freiberger, J; Coulombe, K; Suliman, H; Carraway, M; Piantadosi, C. Superoxide dismutase responds to hyperoxia in rat hippocampus. Undersea and Hyperbaric Medicine. 2004;31:227-232. (2004) Abstract

Freiberger, JJ; Lyman, SJ; Denoble, PJ; Pieper, CF; Vann, RD. Consensus factors used by experts in the diagnosis of decompression illness. Aviation, Space, and Environmental Medicine. 2004;75:1023-1028. (2004) Abstract

Freiberger, JJ; Denoble, PJ; Pieper, CF; Uguccioni, DM; Pollock, NW; Vann, RD. The relative risk of decompression sickness during and after air travel following diving. Aviation, Space, and Environmental Medicine. 2002;73:980-984. (2002) Abstract

Whittington, D; Matsui-Santana, O; Freiberger, JJ; Van Houtven, G; Pattanayak, S. Private demand for a HIV/AIDS vaccine: evidence from Guadalajara, Mexico. Vaccine. 2002;20:2585-2591. (2002) Abstract

Freiberger, JJ; Marsicano, TH. Alprazolam withdrawal presenting as delirium after cardiac surgery. Journal of Cardiothoracic and Vascular Anesthesia. 1991;5:150-152. (1991) Abstract

Freiberger, JJ. An unusual presentation of an airway tear. Anesthesiology. 1984;61:204-206. (1984) Abstract