Department / Division:
Medicine / Infectious Diseases

Address:
DUMC 102359
Hanes House, Room 163
Durham, NC 27710

Appointment Telephone:
Not accepting patients

Fax Telephone:
919-684-8902

• MB ChB, University of Otago (New Zealand), 1993

• Medicine, Christchurch Hospital (New Zealand), 1993-1994
• Surgery, Christchurch Hospital (New Zealand), 1994
• Research Fellow, Centre for Epidemiologic Research in South Africa, Hlabisa Hospital, KwaZulu/Natal (South Africa), 1995
• Internal Medicine, Royal Free Hospital, London (United Kingdom), 1995-1996
• Infectious and Tropical Diseases, Coppetts Wood Hospital, London (United Kingdom), 1996

• HIV/AIDS, Royal Free Hospital, London (United Kingdom), 1996-1997
• Infectious Diseases, Christchurch Hospital (New Zealand), 1997-1998
• Medical Microbiology, Canberra Hospital (Australia), 1999
• Medical Microbiology, Duke University Medical Center, 1999-2000
• Epidemic Intelligence Service, Centers for Disease Control and Prevention, 2000-2002

• Diploma, Tropical Medicine and Hygiene, London School of Hygiene and Tropical Medicine (United Kingdom), 1995
• Member, Royal College of Physicians (United Kingdom), 1997
• Fellow, Royal Australasian College of Physicians, 1999
• Fellow, Royal College of Pathologists of Australasia, 2004

Clinical Interests:
Clinical infectious diseases, clinical microbiology, epidemiology, particularly as practiced in resource-constrained countries

Research Interests:
I am based in northern Tanzania where I am Site Leader for Duke University’s collaborative research program based at Kilimanjaro Christian Medical Centre and Director of Tanzania Operations for the Duke Global Health Institute. I oversee the design and implementation of research studies on infectious diseases, particularly febrile illness, invasive bacterial disease, HIV-associated opportunistic infections, clinical trials of antiretroviral therapy and prevention of mother-to-child transmission of HIV, and infectious diseases diagnostics. In addition, I am a medical epidemiologist with the US Centers for Disease Control and Prevention (CDC). My CDC work focuses on enteric infection epidemiology and prevention in developing countries, particularly invasive salmonelloses.

Representative Publications:
Morpeth SC, Ramadhani HO, Crump JA. Invasive non-Typhi Salmonella disease in Africa. Clin Infect Dis. 2009 Aug 15;49(4):606-11. (2009) Abstract

Morpeth SC, Thielman NM, Ramadhani HO, Hamilton JD, Ostermann J, Kisenge PR, Shao HJ, Reller LB, Itemba DK, Sam NE, Bartlett JA, Shao JF, Crump JA. Effect of trimethoprim-sulfamethoxazole prophylaxis on antimicrobial resistance of fecal Escherichia coli in HIV-infected patients in Tanzania. J Acquir Immune Defic Syndr. 2008 Apr 15;47(5):585-91. (2008) Abstract

Crump JA, Sugarman J. Ethical considerations for short-term experiences by trainees in global health. JAMA. 2008 Sep 24;300(12):1456-8. (2008) Abstract

Crump JA, Kretsinger K, Gay K, Hoekstra RM, Vugia DJ, Hurd S, Segler SD, Megginson M, Luedeman LJ, Shiferaw B, Hanna SS, Joyce KW, Mintz ED, Angulo FJ, . Clinical response and outcome of infection with Salmonella enterica serotype Typhi with decreased susceptibility to fluoroquinolones: a United States foodnet multicenter retrospective cohort study. Antimicrob Agents Chemother. 2008 Apr;52(4):1278-84. (2008) Abstract

Ramadhani HO, Thielman NM, Landman KZ, Ndosi EM, Gao F, Kirchherr JL, Shah R, Shao HJ, Morpeth SC, McNeill JD, Shao JF, Bartlett JA, Crump JA. Predictors of incomplete adherence, virologic failure, and antiviral drug resistance among HIV-infected adults receiving antiretroviral therapy in Tanzania. Clin Infect Dis. 2007 Dec 1;45(11):1492-8. (2007) Abstract

Thielman NM, Chu HY, Ostermann J, Itemba DK, Mgonja A, Mtweve S, Bartlett JA, Shao JF, Crump JA. Cost-Effectiveness of Free HIV Voluntary Counseling and Testing Through a Community-Based AIDS Service Organization in Northern Tanzania. Am J Public Health. 2006 Jan;96(1):114-9. (2006) Abstract

Crump JA, Otieno PO, Slutsker L, Keswick BH, Rosen DH, Hoekstra RM, Vulule JM, Luby SP. Household based treatment of drinking water with flocculant-disinfectant for preventing diarrhoea in areas with turbid source water in rural western Kenya: cluster randomised controlled trial. BMJ. 2005 Sep 3;331(7515):478. (2005) Abstract

Crump JA, Luby SP, Mintz ED. The global burden of typhoid fever. Bull World Health Organ. 2004 May;82(5):346-53. (2004) Abstract

Crump JA, Reller LB. Two decades of disseminated tuberculosis at a university medical center: the expanding role of mycobacterial blood culture. Clin Infect Dis. 2003 Oct 15;37(8):1037-43. (2003) Abstract